Results 21 to 30 of about 2,532,098 (296)

Discovery of (-)-epigallocatechin gallate, a novel olfactory receptor 2AT4 agonist that regulates proliferation and apoptosis in leukemia cells. [PDF]

Heliyon
Choi YR, Na HJ, Lee JA, Kim Y, Kim YS, Kim MJ.   +5 more
europepmc   +2 more sources

Single-cell transcriptomes of developing and adult olfactory receptor neurons in Drosophila

bioRxiv, 2020
Recognition of environmental cues is essential for the survival of all organisms. Precise transcriptional changes occur to enable the generation and function of the neural circuits underlying sensory perception.
C. McLaughlin, Maria Brbic, Qijing Xie, Tongchao Li, Felix Horns, Sai Saroja Kolluru, Justus M. Kebschull, David Vacek, Anthony Xie, Jiefu Li, Robert C. Jones, J. Leskovec, S. Quake, L. Luo, Hongjie Li   +14 more
semanticscholar   +1 more source

Pathogenesis of Olfactory Disorders in COVID-19

Brain Sciences, 2022
Since the outbreak of the SARS-CoV-2 pandemic, olfactory disorders have been reported as a frequent symptom of COVID-19; however, its pathogenesis is still debated.
Laura Ziuzia-Januszewska, Marcin Januszewski   +1 more
doaj   +1 more source

Olfactory receptor and circuit evolution promote host specialisation

Nature, 2020
The evolution of animal behaviour is poorly understood 1 , 2 . Despite numerous correlations between interspecific divergence in behaviour and nervous system structure and function, demonstrations of the genetic basis of these behavioural differences ...
Thomas O. Auer, Mohammed A. Khallaf, Ana F. Silbering, G. Zappia, K. Ellis, Raquel Álvarez-Ocaña, J. R. Arguello, Bill S. Hansson, G. Jefferis, S. Caron, M. Knaden, R. Benton   +11 more
semanticscholar   +1 more source

Tph2-/- female mice restore socio-sexual recognition through upregulating ERα and OTR genes in the amygdala. [PDF]

PLoS ONE, 2018
The central 5-hydroxytryptamine system impairs sociosexual behaviors and olfaction preferences in sexually naive mice. However, it remains unknown whether reproductive experiences impart an effect on the sexual olfactory preferences of female mice ...
Ying Huo, Yaohua Zhang, Huifen Guo, Yingjuan Liu, Qi Fang, Jianxu Zhang   +5 more
doaj   +1 more source

Organization and distribution of glomeruli in the bowhead whale olfactory bulb [PDF]

PeerJ, 2015
Although modern baleen whales (Mysticeti) retain a functional olfactory system that includes olfactory bulbs, cranial nerve I and olfactory receptor genes, their olfactory capabilities have been reduced to a great degree.
Takushi Kishida, JGM Thewissen, Sharon Usip, Robert S. Suydam, John C. George   +4 more
doaj   +2 more sources

The giant pouched rat (Cricetomys ansorgei) olfactory receptor repertoire.

PLoS ONE, 2020
For rodents, olfaction is essential for locating food, recognizing mates and competitors, avoiding predators, and navigating their environment. It is thought that rodents may have expanded olfactory receptor repertoires in order to specialize in ...
Angela R Freeman, Alexander G Ophir, Michael J Sheehan   +2 more
doaj   +1 more source

Synaptophysin and synaptoporin expression in the developing rat olfactory system [PDF]

, 1993
The expressions of two closely related synaptic vesicle antigens synaptophysin and synaptoporin were examined in the olfactory system of the adult rat and during pre- and postnatal development.
Bayer, Bergmann, Betz, Bixby, Breipohl, Brunjes, Elferink, Farbman, Farbman, Fletcher, Geppert, Gesteland, Graziadei, Halász, Halász, Hinds, Hsu, Huttner, Jahn, Jahn, Knaus, Kosaka, Lahr, Lahr, Leube, Mandell, Marchand, Margolis, Marquèze-Pouey, Matteoli, McLean, Navone, Ovtscharoff, Pedersen, Rehn, Schwob, Schwob, Shipley, Smotherman, Specht, Specht, Südhof, Thomas, Thomas, Tixier-Vidal, Trimble, Van Lookeren Campagne, Verhaagen, Wendland, Wiedenmann, Zhong   +50 more
core   +1 more source

Designer lipid-like peptides [PDF]

, 2011
A crucial bottleneck in membrane protein studies, particularly G-protein coupled receptors, is the notorious difficulty of finding an optimal detergent that can solubilize them and maintain their stability and function. Here we report rapid production of
Baaske, Philipp, Braun, Dieter, Brown, Emily, Corin, Karolina, Duhr, Stefan, Jerabek-Willemsen, Moran, Luo, Yuan, Ravel, Deepali B., Song, Junyao, Wang, Xiaoqiang, Wienken, Christoph J., Zhang, Shuguang   +11 more
core   +1 more source

Drosophila olfactory receptors as classifiers for volatiles from disparate real world applications [PDF]

, 2014
Olfactory receptors evolved to provide animals with ecologically and behaviourally relevant information. The resulting extreme sensitivity and discrimination has proven useful to humans, who have therefore co-opted some animals' sense of smell.
Amalia Z Berna, Chang C C, Coral G Warr, de Bruyne M, Marien de Bruyne, Stephen C Trowell, Thomas Nowotny, Zhang X   +7 more
core   +1 more source