Results 31 to 40 of about 145,746 (359)

Cyclic nucleotide-gated channels: structural basis of ligand efficacy and allosteric modulation [PDF]

open access: yes, 1997
Most working proteins, including metabolic enzymes, transcription regulators, and membrane receptors, transporters, and ion channels, share the property of allosteric coupling. The term 'allosteric' means that these proteins mediate indirect interactions
Lester, Henry A.   +2 more
core   +1 more source

Olfactory receptor–dependent receptor repression in Drosophila [PDF]

open access: yesScience Advances, 2021
Feedback mechanisms ensure the exclusive expression of olfactory receptors in Drosophila .
Kaan Mika   +7 more
openaire   +6 more sources

Expressing exogenous functional odorant receptors in cultured olfactory sensory neurons

open access: yesNeural Development, 2008
Background Olfactory discrimination depends on the large numbers of odorant receptor genes and differential ligand-receptor signaling among neurons expressing different receptors.
Fomina Alla F   +3 more
doaj   +1 more source

Decoding the olfactory map through targeted transcriptomics links murine olfactory receptors to glomeruli

open access: yesNature Communications, 2022
Targeted spatial transcriptomics mapped olfactory receptor mRNAs to sections of the murine olfactory bulb to generate an interactive, statistical, 3D model of glomeruli locations and identify an ultra-sensitive receptor-odorant relationship.
Kevin W. Zhu   +6 more
doaj   +1 more source

Neuroethology of olfactory-guided behavior and its potential application in the control of harmful insects [PDF]

open access: yes, 2016
Harmful insects include pests of crops and storage goods, and vectors of human and animal diseases. Throughout their history, humans have been fighting them using diverse methods.
Guerenstein, Pablo Gustavo   +2 more
core   +2 more sources

A unified nomenclature for vertebrate olfactory receptors [PDF]

open access: yesBMC Evolutionary Biology, 2019
Abstract Background Olfactory receptors (ORs) are G protein-coupled receptors with a crucial role in odor detection. A typical mammalian genome harbors ~1000 OR genes and pseudogenes; however, different gene duplication/deletion events have occurred in each species, resulting in complex orthology relationships.
Tsviya Olender   +4 more
openaire   +6 more sources

Functional Reintegration of Sensory Neurons and Transitional Dendritic Reduction of Mitral/Tufted Cells during Injury-Induced Recovery of the Larval Xenopus Olfactory Circuit

open access: yesFrontiers in Cellular Neuroscience, 2017
Understanding the mechanisms involved in maintaining lifelong neurogenesis has a clear biological and clinical interest. In the present study, we performed olfactory nerve transection on larval Xenopus to induce severe damage to the olfactory circuitry ...
Sara J. Hawkins   +13 more
doaj   +1 more source

Evolution of insect olfactory receptors

open access: yeseLife, 2014
The olfactory sense detects a plethora of behaviorally relevant odor molecules; gene families involved in olfaction exhibit high diversity in different animal phyla. Insects detect volatile molecules using olfactory (OR) or ionotropic receptors (IR) and in some cases gustatory receptors (GRs).
Missbach, Christine   +6 more
openaire   +7 more sources

Olfaction and Pheromones: Uncanonical Sensory Influences and Bulbar Interactions

open access: yesFrontiers in Neuroanatomy, 2017
The rodent main and accessory olfactory systems (AOS) are considered functionally and anatomically segregated information-processing pathways. Each system is devoted to the detection of volatile odorants and pheromones, respectively.
Víctor Vargas-Barroso   +2 more
doaj   +1 more source

High-throughput ligand profile characterization in novel cell lines expressing seven heterologous insect olfactory receptors for the detection of volatile plant biomarkers

open access: yesScientific Reports, 2023
Agriculturally important crop plants emit a multitude of volatile organic compounds (VOCs), which are excellent indicators of their health status and their interactions with pathogens and pests. In this study, we have developed a novel cellular olfactory
Katalin Zboray   +9 more
doaj   +1 more source

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