Results 31 to 40 of about 2,532,098 (296)

Lhx2/Ldb1-mediated trans interactions regulate olfactory receptor choice

Nature, 2018
The genome is partitioned into topologically associated domains and genomic compartments with shared chromatin valence. This architecture is constrained by the DNA polymer, which precludes interactions between genes on different chromosomes.
K. Monahan, Adan Horta, S. Lomvardas
semanticscholar   +1 more source

Cryo-EM structure of the insect olfactory receptor Orco

Nature, 2018
The olfactory system must recognize and discriminate amongst an enormous variety of chemicals in the environment. To contend with such diversity, insects have evolved a family of odorant-gated ion channels comprised of a highly conserved co-receptor ...
J. Butterwick, J. D. del Mármol, Kelly H. Kim, Martha A. Kahlson, Jackson A. Rogow, T. Walz, V. Ruta   +6 more
semanticscholar   +1 more source

SARS-CoV-2 receptor and entry genes are expressed by sustentacular cells in the human olfactory neuroepithelium

bioRxiv, 2020
Various reports indicate an association between COVID-19 and anosmia, suggesting an infection of the olfactory sensory epithelium, and thus a possible direct virus access to the brain.
Leon Fodoulian, Joël Tuberosa, D. Rossier, Madlaina Boillat, Chenda Kan, Véronique Pauli, K. Egervari, J. Lobrinus, B. Landis, A. Carleton, I. Rodriguez   +10 more
semanticscholar   +1 more source

Predicting the receptive range of olfactory receptors. [PDF]

PLoS Computational Biology, 2008
Although the family of genes encoding for olfactory receptors was identified more than 15 years ago, the difficulty of functionally expressing these receptors in an heterologous system has, with only some exceptions, rendered the receptive range of given
Rafi Haddad, Liran Carmel, Noam Sobel, David Harel   +3 more
doaj   +1 more source

Short-term memory trace mediated by termination kinetics of olfactory receptor. [PDF]

, 2016
Odorants activate receptors in the peripheral olfactory neurons, which sends information to higher brain centers where behavioral valence is determined.
Boyle, Sean Michael, McInally, Shane, Ray, Anandasankar, Tharadra, Sana   +3 more
core   +1 more source

CD36 is involved in oleic acid detection by the murine olfactory system.

Frontiers in Cellular Neuroscience, 2015
Olfactory signals influence food intake in a variety of species. To maximize the chances of finding a source of calories, an animal’s preference for fatty foods and triglycerides already becomes apparent during olfactory food search behavior.
Sonja eOberland, Sonja eOberland, Tobias eAckels, Tobias eAckels, Stefanie eGaab, Thomas ePelz, Thomas ePelz, Jennifer eSpehr, Marc eSpehr, Eva Maria Neuhaus, Eva Maria Neuhaus   +10 more
doaj   +1 more source

Perception space - The final frontier [PDF]

, 2005
Mapping the complex sensory behavior of animals, such as smell in bees, to relevant neural activity provides clues into how animals perceive and respond to the world through their ...
Brockmann, A, Chittka, L
core   +3 more sources

Olfactory receptor OR2AT4 regulates human hair growth

Nature Communications, 2018
Olfactory receptors are expressed by different cell types throughout the body and regulate physiological cell functions beyond olfaction. In particular, the olfactory receptor OR2AT4 has been shown to stimulate keratinocyte proliferation in the skin ...
J. Chéret, M. Bertolini, L. Ponce, J. Lehmann, Teresa Tsai, M. Alam, H. Hatt, R. Paus   +7 more
semanticscholar   +1 more source

Widespread receptor-driven modulation in peripheral olfactory coding

Science, 2020
The perception of complex scents It is generally assumed that olfactory receptors faithfully report information to the brain in the form of a linear, additive code.
Lu Xu, Wenze Li, Venkatakaushik Voleti, D. Zou, E. Hillman, S. Firestein   +5 more
semanticscholar   +1 more source

Computational modeling of the olfactory receptor Olfr73 suggests a molecular basis for low potency of olfactory receptor-activating compounds

Communications Biology, 2019
The mammalian olfactory system uses hundreds of specialized G-protein-coupled olfactory receptors (ORs) to discriminate a nearly unlimited number of odorants. Cognate agonists of most ORs have not yet been identified and potential non-olfactory processes
Shuguang Yuan, T. Dahoun, Marc Brugarolas, H. Pick, S. Filipek, H. Vogel   +5 more
semanticscholar   +1 more source