Essential role for PDGF signaling in ophthalmic trigeminal placode induction [PDF]
, 2008 Much of the peripheral nervous system of the head is derived from ectodermal thickenings, called placodes, that delaminate or invaginate to form cranial ganglia and sense organs.
Bronner-Fraser, Marianne +1 more
core +1 more source
Olfactory sensory neurons transiently express multiple olfactory receptors during development
Molecular Systems Biology, 2015 In mammals, each olfactory sensory neuron randomly expresses one, and only one, olfactory receptor (OR)--a phenomenon called the "one-neuron-one-receptor" rule. Although extensively studied, this rule was never proven for all ~1,000 OR genes in one cell at once, and little is known about its dynamics.
Tan, Longzhi, Li, Qian, Xie, X Sunney
openaire +4 more sources
GPRC5C regulates the composition of cilia in the olfactory system
BMC Biology, 2023 Background Olfactory sensory neurons detect odourants via multiple long cilia that protrude from their dendritic endings. The G protein-coupled receptor GPRC5C was identified as part of the olfactory ciliary membrane proteome, but its function and ...
Sneha Bhat +6 more
doaj +1 more source
Odour perception in the codling moth Cydia pomonella L. [PDF]
, 2004 The codling moth, Cydia pomonella L. (Lepidoptera: Tortricidae) is a renowned pest in apple, pear and walnut orchards, and its activities are in large guided by volatile odours as sensory cues.
Ansebo, Lena
core
The Role of Ionic Liquids at the Biological Interfaces in Bioelectronics
Advanced Science, EarlyView.Ionic liquids (ILs) are highlighted as key artificial ionic materials that bridge biological ion‐based signaling and electronic devices. By understanding their composition, structure, function relationships, and mechanisms, ILs can advance from high performance electrolyte to core materials enabling integrated, multifunctional bioelectronics for ...
Yeong‐sinn Ye +5 more
wiley +1 more source
Neurons and circuits for odor processing in the piriform cortex [PDF]
, 2013 Increased understanding of the early stages of olfaction has lead to a renewed interest in the higher brain regions responsible for forming unified ‘odor images’ from the chemical components detected by the nose.
Bekkers, John MacDonald +1 more
core +1 more source
Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Advanced Science, EarlyView.Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source
Trpc2-Expressing Sensory Neurons in the Main Olfactory Epithelium of the Mouse
Cell Reports, 2014 The mouse olfactory system contains two distinct chemosensory epithelia, the main olfactory epithelium (MOE) and the vomeronasal epithelium (VNE). Their sensory neurons express odorant receptor genes and vomeronasal receptor genes, respectively, and ...
Masayo Omura, Peter Mombaerts
doaj +1 more source
Alzheimer’s Disease: What Can We Learn From the Peripheral Olfactory System?
Frontiers in Neuroscience, 2020 The sense of smell has been shown to deteriorate in patients with some neurodegenerative disorders. In Parkinson’s disease (PD) and Alzheimer’s disease (AD), decreased ability to smell is associated with early disease stages.
Michele Dibattista +3 more
doaj +1 more source
Chromatin Modulatory Proteins and Olfactory Receptor Signaling in the Refinement and Maintenance of Fruitless Expression in Olfactory Receptor Neurons. [PDF]
PLoS Biology, 2016 During development, sensory neurons must choose identities that allow them to detect specific signals and connect with appropriate target neurons. Ultimately, these sensory neurons will successfully integrate into appropriate neural circuits to generate ...
Catherine E Hueston +6 more
doaj +1 more source