Results 71 to 80 of about 58,593 (265)
The gustatory system influences "Drosophila" lifespan [PDF]
, 2011 The lifespan of an organism is affected by the complex interplay between genetic and environmental factors. In C. elegans, this interaction between genes and environment is mediated by the sensory system.
Ostojić, Ivan
core +1 more source
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
Advanced Science, EarlyView.This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
Trpc2-Expressing Sensory Neurons in the Main Olfactory Epithelium of the Mouse
Cell Reports, 2014 The mouse olfactory system contains two distinct chemosensory epithelia, the main olfactory epithelium (MOE) and the vomeronasal epithelium (VNE). Their sensory neurons express odorant receptor genes and vomeronasal receptor genes, respectively, and ...
Masayo Omura, Peter Mombaerts
doaj +1 more source
Alzheimer’s Disease: What Can We Learn From the Peripheral Olfactory System?
Frontiers in Neuroscience, 2020 The sense of smell has been shown to deteriorate in patients with some neurodegenerative disorders. In Parkinson’s disease (PD) and Alzheimer’s disease (AD), decreased ability to smell is associated with early disease stages.
Michele Dibattista +3 more
doaj +1 more source
Most primary olfactory neurons have individually neutral effects on behavior
eLife, 2022 Animals use olfactory receptors to navigate mates, food, and danger. However, for complex olfactory systems, it is unknown what proportion of primary olfactory sensory neurons can individually drive avoidance or attraction.
Tayfun Tumkaya +5 more
doaj +1 more source
Advanced Science, EarlyView.The cellular actors of oxytocin signaling are under intense scrutiny. A brain‐wide anatomical and functional analysis in mice and rats reveals widespread expression of oxytocin receptors in astrocytes. These receptors are functionally active and, in the nucleus accumbens, selectively regulate male social affiliation.
Clémence Denis +32 more
wiley +1 more source
Advanced Science, EarlyView.Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan +8 more
wiley +1 more source
Olfactory Neurons and Brain Centers Directing Oviposition Decisions in Drosophila
Cell Reports, 2018 Summary: The sense of smell influences many behaviors, yet how odors are represented in the brain remains unclear. A major challenge to studying olfaction is the lack of methods allowing activation of specific types of olfactory neurons in an ...
Sonia G. Chin +4 more
doaj +1 more source
Advanced Science, EarlyView.Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas +6 more
wiley +1 more source
Axonal Odorant Receptors Mediate Axon Targeting
Cell Reports, 2019 Summary: In mammals, odorant receptors not only detect odors but also define the target in the olfactory bulb, where sensory neurons project to give rise to the sensory map.
Ilaria Zamparo +12 more
doaj +1 more source