Cellular Profiles of Prodynorphin and Preproenkephalin mRNA-Expressing Neurons in the Anterior Olfactory Tubercle of Mice. [PDF]
Front Neural Circuits, 2022 The olfactory tubercle (OT) is a striatal region that receives olfactory inputs. mRNAs of prodynorphin (Pdyn) and preproenkephalin (Penk), precursors of dynorphins and enkephalins, respectively, are strongly expressed in the striatum. Both produce opioid
Maegawa A +4 more
europepmc +4 more sources
Interhemispheric asymmetry of c-Fos expression in glomeruli and the olfactory tubercle following repeated odor stimulation. [PDF]
FEBS Open Bio, 2020 Odor adaptation allows the olfactory system to regulate sensitivity to different stimulus intensities, which is essential for preventing saturation of the cell‐transducing machinery and maintaining high sensitivity to persistent and repetitive odor ...
Jae Y, Lee N, Moon DW, Koo J.
europepmc +4 more sources
Hypothetical Roles of the Olfactory Tubercle in Odor-Guided Eating Behavior. [PDF]
Front Neural Circuits, 2020 Olfaction plays an important role in the evaluation, motivation, and palatability of food. The chemical identity of odorants is coded by a spatial combination of activated glomeruli in the olfactory bulb, which is referred to as the odor map.
Murata K.
europepmc +5 more sources
Synaptic plasticity and roles of orexin in distinct domains of the olfactory tubercle. [PDF]
Front Neural CircuitsOlfactory behavior is highly plastic, and the olfactory tubercle (OT), a component of the olfactory cortex and ventral striatum, includes anteromedial (amOT) and lateral (lOT) domains with roles in attractive and aversive olfactory behavioral learning ...
Podder S +4 more
europepmc +4 more sources
Opposing Roles of Dopamine Receptor D1- and D2-Expressing Neurons in the Anteromedial Olfactory Tubercle in Acquisition of Place Preference in Mice. [PDF]
Front Behav Neurosci, 2019 Olfaction induces adaptive motivated behaviors. Odors associated with food induce attractive behavior, whereas those associated with dangers induce aversive behavior.
Murata K +7 more
europepmc +5 more sources
Distinct representation of cue-outcome association by D1 and D2 neurons in the ventral striatum's olfactory tubercle. [PDF]
Elife, 2022 Positive and negative associations acquired through olfactory experience are thought to be especially strong and long-lasting. The conserved direct olfactory sensory input to the ventral striatal olfactory tubercle (OT) and its convergence with dense ...
Martiros N, Kapoor V, Kim SE, Murthy VN.
europepmc +4 more sources
Phasic dopamine reinforces distinct striatal stimulus encoding in the olfactory tubercle driving dopaminergic reward prediction. [PDF]
Nat Commun, 2020 It is not entirely understood how network plasticity produces the coding of predicted value during stimulus-outcome learning. Here, the authors reveal a reinforcing loop in distributed limbic circuits, transforming sensory stimuli into reward prediction ...
Oettl LL +9 more
europepmc +4 more sources
Embryonic and postnatal development of mouse olfactory tubercle. [PDF]
Mol Cell Neurosci, 2019 Martin-Lopez E +4 more
europepmc +3 more sources
Distinct limbic dopamine regulation across olfactory-tubercle subregions through integration of in vivo fast-scan cyclic voltammetry and optogenetics. [PDF]
J Neurochem, 2022 Bhimani RV, Yates R, Bass CE, Park J.
europepmc +3 more sources
Glutamatergic Neurons in the Piriform Cortex Influence the Activity of D1- and D2-Type Receptor-Expressing Olfactory Tubercle Neurons. [PDF]
J Neurosci, 2019 White KA +12 more
europepmc +3 more sources