Results 251 to 260 of about 85,792 (299)
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Neurologic Clinics, 1995
Although it was initially thought to be a passive structure, the oligodendrocyte and myelin unit is now considered highly dynamic with many important functions beyond its role in myelination. Inhibitors of neurite growth can be localized to oligodendrocyte and myelin, highlighting the importance of oligodendrocytes in general CNS maintenance and in ...
J A, McLaurin, V W, Yong
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Although it was initially thought to be a passive structure, the oligodendrocyte and myelin unit is now considered highly dynamic with many important functions beyond its role in myelination. Inhibitors of neurite growth can be localized to oligodendrocyte and myelin, highlighting the importance of oligodendrocytes in general CNS maintenance and in ...
J A, McLaurin, V W, Yong
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Oligodendrocytic Gliomatosis Cerebri
Acta Neurochirurgica, 2000We describe a very unusual case of gliomatosis cerebri (GC) with oligodendrocytic differentiation. A 65-year-old man presented with a convulsive seizure. Magnetic resonance (MR) documented diffuse enlargement of cerebral hemispheres, brainstem, and right cerebellar hemisphere.
Tancredi, A +4 more
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Oligodendrocyte differentiation
2016In the nervous system, axons transmit information in the form of electrical impulses over long distances. The speed of impulse conduction is enhanced by myelin, a lipid-rich membrane that wraps around axons. Myelin also is required for the long-term health of axons by providing metabolic support.
E S, Mathews, B, Appel
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The Role of Oligodendrocytes and Oligodendrocyte Progenitors in cns Remyelination
1999Remyelination enables restoration of saltatory conduction and a return of normal function lost during demyelination. Unfortunately, remyelination is often incomplete in the adult human central nervous system (CNS) and this failure of remyelination is one of the main reasons for clinical deficits in demyelinating disease. An understanding of the failure
H S, Keirstead, W F, Blakemore
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Trends in Neurosciences, 1996
In the adult vertebrate CNS, oligodendrocytes are ubiquitously distributed throughout white matter. By contrast, in the embryonic CNS, recent studies suggest that oligodendrocyte precursors arise in a discrete ventral location. Thus, local ventral environmental signals that contribute to the overall patterning of the CNS are likely to influence the ...
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In the adult vertebrate CNS, oligodendrocytes are ubiquitously distributed throughout white matter. By contrast, in the embryonic CNS, recent studies suggest that oligodendrocyte precursors arise in a discrete ventral location. Thus, local ventral environmental signals that contribute to the overall patterning of the CNS are likely to influence the ...
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Regulation of oligodendrocyte development
Microscopy Research and Technique, 2001AbstractOligodendrocytes are myelinating cells in the central nervous system. Recent studies demonstrated that oligodendrocyte progenitor cells are generated from a restricted region in the ventricular zone. In the rodent spinal cord, progenitor cells appear from narrow and bilateral longitudinal columns in the ventral ventricular zone, and then ...
T, Kagawa, T, Wada, K, Ikenaka
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Oligodendrocytes and Alzheimer's disease
International Journal of Neuroscience, 2015Extensive evidence has indicated that the breakdown of myelin is associated with Alzheimer's disease (AD) since the vulnerability of oligodendrocytes under Alzheimer's pathology easily induces the myelin breakdown and the loss of the myelin sheath which might be the initiating step in the changes of the earliest stage of AD prior to appearance of ...
Zhiyou, Cai, Ming, Xiao
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The oligodendrocytic junctional complex
Cell and Tissue Research, 1978The junctional complex of oligodendrocytes was studied by means of different electron microscopical techniques. This complex is composed of the following junctional membrane formations: 1) tight junctional domains in the oligodendrocytic membrane near the some of the cells, 2) fasciae occludentes or focal tight junctions on the outer oligodendrocytic ...
R, Dermietzel, D, Schünke, A, Leibstein
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Tight junctions of oligodendrocytes
Cell and Tissue Research, 1977Freeze-fracture replicas of the rat corpus callosum revealed prominent junctional strands in fractured cell membranes of the somata of oligodendrocytes. The junctional strands were characterized by an elaborate system of straight or slightly undulating rows of linear aggregates of particles or ridges in the P face and furrows in the E face.
E, Tani, T, Itagaki, M, Nakano
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Expression of plasmolipin in oligodendrocytes
Journal of Neuroscience Research, 1991AbstractPlasmolipin is a plasma membrane proteolipid which has recently been described as a component of myelin (Cochary et al.: Journal of Neurochemistry 55:602–610, 1990). The present study reports the expression and localization of plasmolipin in primary glial cultures and secondary oligooendrocyte cultures.
I, Fischer +3 more
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