Results 261 to 270 of about 108,437 (306)
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Oligodendrocytes and Alzheimer's disease
International Journal of Neuroscience, 2015Extensive evidence has indicated that the breakdown of myelin is associated with Alzheimer's disease (AD) since the vulnerability of oligodendrocytes under Alzheimer's pathology easily induces the myelin breakdown and the loss of the myelin sheath which might be the initiating step in the changes of the earliest stage of AD prior to appearance of ...
Zhiyou, Cai, Ming, Xiao
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Regulation of oligodendrocyte development
Molecular Neurobiology, 1998Oligodendrocytes are the cells responsible for the formation of myelin in the central nervous system. Recent studies demonstrated that cells of the oligodendrocyte lineage initially arise in distinct regions of the ventricular zone during early development.
D M, Orentas, R H, Miller
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The oligodendrocytic junctional complex
Cell and Tissue Research, 1978The junctional complex of oligodendrocytes was studied by means of different electron microscopical techniques. This complex is composed of the following junctional membrane formations: 1) tight junctional domains in the oligodendrocytic membrane near the some of the cells, 2) fasciae occludentes or focal tight junctions on the outer oligodendrocytic ...
R, Dermietzel, D, Schünke, A, Leibstein
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Regulation of oligodendrocyte development
Microscopy Research and Technique, 2001AbstractOligodendrocytes are myelinating cells in the central nervous system. Recent studies demonstrated that oligodendrocyte progenitor cells are generated from a restricted region in the ventricular zone. In the rodent spinal cord, progenitor cells appear from narrow and bilateral longitudinal columns in the ventral ventricular zone, and then ...
T, Kagawa, T, Wada, K, Ikenaka
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Oligodendrocytes, GRPs and MNOPs
Trends in Neurosciences, 2003What about earlier stages? At developmental stages earlier than E16, expression of Olig1 and Olig2 is limited to a large ventral domain of the proliferating ventricular zone that is known to generate both motoneurons and oligodendrocytes. If Olig2 expression is confined to an oligodendrocyte–motoneuron precursor, then its expression should not be seen ...
Ying, Liu, Mahendra, Rao
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Regulators of Oligodendrocyte Differentiation
Cold Spring Harbor Perspectives in BiologyMyelination has evolved as a mechanism to ensure fast and efficient propagation of nerve impulses along axons. Within the central nervous system (CNS), myelination is carried out by highly specialized glial cells, oligodendrocytes. The formation of myelin is a prolonged aspect of CNS development that occurs well into adulthood in humans, continuing ...
Ben, Emery, Teresa L, Wood
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Oligodendrocyte–Neuron Myelinating Coculture
2019The preparation of oligodendrocytes and neurons independently in vitro has provided substantial insight into the biology of the process of myelin sheath formation. This chapter describes a myelination system of dorsal root ganglion neurons by independent isolation of oligodendrocyte progenitor cells from either rat or mouse cortex.
Swire, Matthew +1 more
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Comptes rendus des seances de la Societe de biologie et de ses filiales, 1996
The mechanisms leading to cell diversification in the Vertebrate central nervous system are still poorly understood. We have analyzed neural differentiation potentialities of the embryonic chick optic nerve. In the adult, the optic nerve is made up of astrocytes and oligodendrocytes ensheathing retinal axons, but it is entirely devoid of neuronal cell ...
P, Cochard, M C, Giess
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The mechanisms leading to cell diversification in the Vertebrate central nervous system are still poorly understood. We have analyzed neural differentiation potentialities of the embryonic chick optic nerve. In the adult, the optic nerve is made up of astrocytes and oligodendrocytes ensheathing retinal axons, but it is entirely devoid of neuronal cell ...
P, Cochard, M C, Giess
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Neuron/Oligodendrocyte Myelination Coculture
2018Myelination cell culture systems are useful tools for studying myelin biology and myelin-related disorders. Compared to a number of established protocols for dissociated pure oligodendrocyte (OL) culture, methods for myelination culture are limited.
Yi, Pang +3 more
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2001
Abstract Oligodendrocytes, like other neural cells in the central nervous system (CNS), develop from the neuroepithelial precursors that line the lumen of the spinal cord and the ventricles of the brain—the so-called ventricular zone (VZ).
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Abstract Oligodendrocytes, like other neural cells in the central nervous system (CNS), develop from the neuroepithelial precursors that line the lumen of the spinal cord and the ventricles of the brain—the so-called ventricular zone (VZ).
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