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Regulation of oligodendrocyte development
Molecular Neurobiology, 1998Oligodendrocytes are the cells responsible for the formation of myelin in the central nervous system. Recent studies demonstrated that cells of the oligodendrocyte lineage initially arise in distinct regions of the ventricular zone during early development.
D M, Orentas, R H, Miller
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Oligodendrocyte degeneration in AD
Neurobiology of Aging, 2004Most would agree with a description of Alzheimer’s disease (AD) primarily as a degeneration of the cerebral cortex. As a result, much laboratory research in the past decade has focused on the cell death mechanisms of neurons. However, it may be time broaden the focus of AD research to include dysfunction of the tracts that connect cortical areas.
G T, Whitman, C W, Cotman
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Regulators of Oligodendrocyte Differentiation
Cold Spring Harbor Perspectives in BiologyMyelination has evolved as a mechanism to ensure fast and efficient propagation of nerve impulses along axons. Within the central nervous system (CNS), myelination is carried out by highly specialized glial cells, oligodendrocytes. The formation of myelin is a prolonged aspect of CNS development that occurs well into adulthood in humans, continuing ...
Ben, Emery, Teresa L, Wood
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GluA2 overexpression in oligodendrocyte progenitors promotes postinjury oligodendrocyte regeneration
Cell Reports, 2021Jonathan Soboloff +2 more
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Calcium Signaling in the Oligodendrocyte Lineage: Regulators and Consequences
Annual Review of Neuroscience, 2020Pablo Páez, David Lyons
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Mechanisms of axonal support by oligodendrocyte-derived extracellular vesicles
Nature Reviews Neuroscience, 2023Eva-Maria Krämer-Albers, Hauke Werner
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Altered human oligodendrocyte heterogeneity in multiple sclerosis
Nature, 2019David van Bruggen +2 more
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