Results 281 to 290 of about 63,056 (297)

Oligodendrocytes, GRPs and MNOPs

Trends in Neurosciences, 2003
What about earlier stages? At developmental stages earlier than E16, expression of Olig1 and Olig2 is limited to a large ventral domain of the proliferating ventricular zone that is known to generate both motoneurons and oligodendrocytes. If Olig2 expression is confined to an oligodendrocyte–motoneuron precursor, then its expression should not be seen ...
Ying Liu, Mahendra S. Rao
openaire   +3 more sources

The oligodendrocytic junctional complex

Cell and Tissue Research, 1978
The junctional complex of oligodendrocytes was studied by means of different electron microscopical techniques. This complex is composed of the following junctional membrane formations: 1) tight junctional domains in the oligodendrocytic membrane near the some of the cells, 2) fasciae occludentes or focal tight junctions on the outer oligodendrocytic ...
R. Dermietzel, A. G. Leibstein, D. Schünke   +2 more
openaire   +3 more sources

Expression of plasmolipin in oligodendrocytes

Journal of Neuroscience Research, 1991
AbstractPlasmolipin is a plasma membrane proteolipid which has recently been described as a component of myelin (Cochary et al.: Journal of Neurochemistry 55:602–610, 1990). The present study reports the expression and localization of plasmolipin in primary glial cultures and secondary oligooendrocyte cultures.
Itzhak Fischer, Giuseppina Romano-Clarke, Elizabeth F. Cochary, J. T. Konola   +3 more
openaire   +3 more sources

Tight junctions of oligodendrocytes

Cell and Tissue Research, 1977
Freeze-fracture replicas of the rat corpus callosum revealed prominent junctional strands in fractured cell membranes of the somata of oligodendrocytes. The junctional strands were characterized by an elaborate system of straight or slightly undulating rows of linear aggregates of particles or ridges in the P face and furrows in the E face.
Tetsuya Itagaki, Masaru Nakano, Eiichi Tani   +2 more
openaire   +3 more sources

Oligodendrocyte degeneration in AD

Neurobiology of Aging, 2004
Most would agree with a description of Alzheimer’s disease (AD) primarily as a degeneration of the cerebral cortex. As a result, much laboratory research in the past decade has focused on the cell death mechanisms of neurons. However, it may be time broaden the focus of AD research to include dysfunction of the tracts that connect cortical areas.
G.T Whitman, Carl W. Cotman
openaire   +3 more sources

Telomerase and oligodendrocyte differentiation

Journal of Neurobiology, 2001
AbstractMyelin in the mammalian central nervous system (CNS) is produced by oligodendrocytes, most of which arise from oligodendrocyte precursor cells (OPCs) during late embryonic and early postnatal development. Both external and internal cues have been implicated in regulating OPC exit from the cell cycle and differentiation into oligodendrocytes. In
Gregg L. Caporaso, Gregg L. Caporaso, Moses V. Chao   +2 more
openaire   +3 more sources

The human oligodendrocyte proteome

PROTEOMICS, 2013
Myelination of the CNS is performed by oligodendrocytes (OLs), which have been implicated in brain disorders, such as multiple sclerosis and schizophrenia. We have used the human oligodendroglial cell line MO3.13 to establish an OL reference proteome database.
Takayuki Manabe, Keiko Iwata, Keiko Iwata, Keiko Iwata, Hideo Matsuzaki, Hideo Matsuzaki, Johann Steiner, Peter Falkai, Cecília Cerqueira Café-Mendes, Cecília Cerqueira Café-Mendes, Andrea Schmitt, Andrea Schmitt, Daniel Martins-de-Souza, Daniel Martins-de-Souza, Daniel Martins-de-Souza, Christoph W. Turck   +15 more
openaire   +3 more sources

The Biology of the Oligodendrocyte

1984
Certain problems in defining the oligodendrocyte cell type should be pointed out at the onset. The interfascicular oligodendrocyte is commonly defined as the cell responsible for the formation and maintenance of central myelin. Direct demonstration of the connections between oligodendrocyte somas and myelin sheaths is inherently very difficult, however,
Richard P. Bunge, Patrick M. Wood
openaire   +2 more sources

RNA Trafficking in Oligodendrocytes

2001
A2RE and hnRNP A2 have been identified as important cis/trans determinants for MBP RNA trafficking in oligodendrocytes. Since A2RE-like sequences are found in several different transported RNAs, and since hnRNP A2 is expressed in most cell types, this may represent a general RNA trafficking pathway shared by a variety of different RNAs in different ...
John H. Carson, Hongyi Cui, Winfried Krueger, Craig L. Brumwell, Boris Schlepchenko, Elisa Barbarese   +5 more
openaire   +3 more sources

Structure and Function of Oligodendrocytes

2004
This chapter deals with the morphology of oligodendrocytes. The first section reviews current findings on the morphology of oligodendrocytes and discusses these findings in the context of the classical work by Rio–Hortega. The second section examines the functional significance of oligodendrocyte polymorphism, and the third deals with the environmental
openaire   +1 more source