Results 161 to 170 of about 113,519 (282)

Anti-TLR2 immunotherapy modulates neuron-to-oligodendrocyte propagation of α-synuclein in mouse and human models. [PDF]

Nat Commun
Bae EJ, Ham S, Jeong YW, Yang WS, Shin J, Lee WJ, Ahn WJ, Yoon YS, Lee HJ, Lee SH, Park SH, Lee SJ.   +11 more
europepmc   +1 more source

SV2A expression in blood cells as a possible biomarker candidate for levetiracetam treatment response

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate whether synaptic vesicle protein 2A (SV2A) expression on peripheral immune cells predicts treatment response to levetiracetam in epilepsy. Methods High‐dimensional flow cytometry was used to prospectively assess SV2A expression on immune cells from levetiracetam responders, nonresponders, and ...
Johannes Lang, Mathias Linnerbauer, Jeanne Cuny, Veit Rothhammer, Hajo Hamer   +4 more
wiley   +1 more source

Brain-wide mapping of oligodendrocyte organization, oligodendrogenesis, and myelin injury. [PDF]

Cell
Xu YKT, Bush A, Musheyev E, Umans J, Zhang L, Kim AA, Zhang S, Eugenin von Bernhardi J, Yan Y, Sulam J, Bergles DE.   +10 more
europepmc   +1 more source

Oligodendrocyte [PDF]

, 2020
openaire   +1 more source

Decoding epilepsy's molecular blueprint: Machine learning unravels transcriptomic subtypes and regulatory networks

Epilepsia, EarlyView.
Abstract Objective Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy. The molecular heterogeneity underlying DRE remains poorly defined, largely due to limited access to resected brain tissue and substantial genetic diversity.
Yanping Weng, Yu Ma, Wanwan Hou, Haibo Li, Yuanfeng Zhou, Rui Zhao, Hao Li, Lian Chen, Yangyang Ma, Li Jin, Yi Wang, Yu An   +11 more
wiley   +1 more source

Single-cell RNA sequencing analysis of bone cancer pain model induced by Lewis lung cancer cells in male mice. [PDF]

Ann Med
Zhou Q, Chen J, Wang H, Jin R, Paerhati H, Zhu X, Dong G, Zhang M, Jiang F.   +8 more
europepmc   +1 more source

Isolated absence epilepsy associated with a de novo FBXW7 missense variant in the F‐box domain

Epilepsia Open, EarlyView.
Abstract The FBXW7 gene encodes a substrate‐recognition component of the Skp1‐Cul1‐F‐box (SCF) E3 ubiquitin ligase complex, which targets key regulatory proteins for proteasomal degradation. Recently, loss‐of‐function FBXW7 variants have been associated with a novel neurodevelopmental disorder characterized by heterogeneous clinical features.
Anees Muhammad, Mohammad Sadegh Shams Nosrati, Alireza Dostmohammadi, Francesca Madia, Maria Margherita Mancardi, Stefania Fornarino, Luca Bosisio, Zahra Hoseini Tavassol, Mir Davood Omrani, Federico Zara, Marcello Scala   +10 more
wiley   +1 more source

Human Myelin Spheres for in Vitro Oligodendrocyte Maturation, Myelination and Neurological Disease Modeling. [PDF]

Stem Cell Rev Rep
Ahuja K, Ramezankhani R, Wang X, Burg T, Amos G, Neyrinck K, Silva A, Arekatla G, Cassidy EE, Nami F, Terryn J, Wierda K, Vints K, Vandamme N, Poovathingal S, Lambrichts I, Swinnen JV, Van Den Bosch L, De Groef L, Moons L, Verfaillie C, Neyts J, Jochmans D, Chai YC.   +23 more
europepmc   +1 more source

A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis

Ibrain, Volume 11, Issue 1, Page 112-116, Spring 2025.
We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo, Piao Cao, Jing‐Qing Xu, Rong Yan, Jian Wang, Tao Liang, Ya Chen, Zu‐Cai Xu   +7 more
wiley   +1 more source

Myelin Lipid Reserves as a Conditional Metabolic Buffer: Implications for Alzheimer's Disease and Ischemic Stroke. [PDF]

Neuromolecular Med
Zou P, Huang Z, Zhang Y, Zong X, Zhang Q.   +4 more
europepmc   +1 more source