Results 161 to 170 of about 114,630 (300)
Personalized Treatment of Patients With Multiple Sclerosis: A Case Report and Literature Review
ABSTRACT Managing multiple sclerosis (MS) with a highly active disease course presents significant challenges, particularly regarding the timing of therapeutic escalation and the preservation of brain volume. We present a personalized management strategy for a 36‐year‐old male with relapsing‐remitting MS (RRMS) who experienced initial misdiagnosis ...
Fengjun Wang +3 more
wiley +1 more source
Teriflunomide Attenuates Demyelination and Enhances Remyelination in Organotypic Brain Slice Cultures Through Modulation of Glial Cell Dynamics. [PDF]
Kronenberg J +8 more
europepmc +1 more source
Abstract Background Neurodevelopmental disorders feature various symptoms that frequently include seizures and motor manifestations, but their attribution to disruptions of specific circuits and molecular alterations is notoriously hard to establish, which limits therapeutic interventions.
Gloria Brunori +9 more
wiley +1 more source
Age-Related Decline in Myelin Markers and Oligodendrocyte Density in Rhesus Macaque Prefrontal Cortex. [PDF]
Zhang Y +5 more
europepmc +1 more source
Early and Progressive Spinal Cord Atrophy in Spinocerebellar Ataxia Type 1
Abstract Background Spinocerebellar ataxia type 1 (SCA1) is a rare, autosomal dominant neurodegenerative disorder characterized by progressive cerebellar and brainstem degeneration. Previous studies have shown that spinal cord atrophy is also a key aspect of SCA1 neuropathology.
Colette J.M. Reniers +11 more
wiley +1 more source
Glial lactate metabolism and transport in Alzheimer's disease. [PDF]
Wang Y +5 more
europepmc +1 more source
Seeing Invisible Oligomers: Rethinking α‐Synuclein Pathology Through Proximity Ligation Assay
Abstract Parkinson's disease (PD) and multiple system atrophy are defined by α‐synuclein (αSYN)‐positive inclusions – Lewy bodies (LBs) and glial cytoplasmic inclusions – yet mounting evidence indicates that these inclusions represent only a fraction of disease‐relevant pathology.
Hiroaki Sekiya +3 more
wiley +1 more source
Developmental Profiling of Structural and Functional Maturation in Mouse Corpus Callosum. [PDF]
Johnson H +4 more
europepmc +1 more source

