Results 81 to 90 of about 202,274 (300)

Competitive adsorption of p-hydroxybenzoic acid and phenol on activated carbon : experimental study and modelling. [PDF]

, 2013
The competitive adsorption of phenol and p-hydroxybenzoic acid (4HBA) has been investigated on activated carbon (AC) for a wide range of concentrations under unbuffered conditions. The results show a preferential adsorption of 4HBA which can be explained
Andriantsiferana, Caroline, Creanga-Manole, Carmen, Delmas, Henri, Julcour-Lebigue, Carine, Wilhelm, Anne-Marie   +4 more
core   +2 more sources

Hierarchically Engineered Multi‐Enzyme Nanoreactors for in vitro Drug Biosynthesis and Pathway Transplantation Into Cells

Advanced Materials, EarlyView.
A hierarchically structured metal–organic framework (eMIL) is shown to host the complete six‐enzyme biosynthesis pathway for the anti‐cancer pigment violacein, reshaping reaction dynamics and multiplying in vitro yields. eMIL nanoreactors deliver this reconstituted bacterial multi‐protein system into mammalian cells, where cell‐derived substrates and ...
Ainur Sharip, Somayah S. Qutub, Manar M. Farooqui, Walaa Baslyman, Nida Khalfay, Lukman O. Alimi, Patricia Lopez Sanchez, Lingyun Zhao, Milena Chernyshevskaia, Giovanni Colombo, Niveen M. Khashab, Stefan T. Arold, Raik Grünberg   +12 more
wiley   +1 more source

Hantavirus Nucleocapsid Protein Oligomerization [PDF]

Journal of Virology, 2001
ABSTRACT Hantaviruses are enveloped, negative-strand RNA viruses which can be lethal to humans, causing either a hemorrhagic fever with renal syndrome or a hantaviral pulmonary syndrome. The viral genomes consist of three RNA segments: the L segment encodes the viral polymerase, the M segment encodes the viral surface glycoproteins G1 and G2,
A, Alfadhli, Z, Love, B, Arvidson, J, Seeds, J, Willey, E, Barklis   +5 more
openaire   +2 more sources

Zirconium and titanium complexes supported by tridentate LX2 ligands having two phenolates linked to furan, thiophene, and pyridine donors: precatalysts for propylene polymerization and oligomerization [PDF]

, 2008
Zirconium and titanium complexes with tridentate bis(phenolate)-donor (donor = pyridine, furan and thiophene) ligands have been prepared and investigated for applications in propylene polymerization.
Agapie, Theodor, Bercaw, John E., DiPasquale, Antonio G., Henling, Lawrence M., Rheingold, Arnold L.   +4 more
core   +2 more sources

GSH‐Responsive Nanoparticles Enhance Hepatocellular Carcinoma Immunotherapy Through Synergistic Effects of Cuproptosis and PI3K Inhibitor Combination

Advanced Science, EarlyView.
ABSTRACT Cuproptosis, an emerging form of programmed cell death, is capable of inducing mitochondrial dysfunction. Moreover, the PI3K‐AKT‐mTOR signaling pathway contributes to tumor cell progression by reprogramming mitochondrial morphology and function.
Lei Wu, Jintong Na, Xiyu Liu, Dongsheng Tang, Zhungang Yang, Zheng Cao, Xinyue He, Haihua Xiao, Liping Zhong, Yuan Liao, Yongxiang Zhao   +10 more
wiley   +1 more source

Characteristics, Structure, and Biological Role of Stefins (type-1 cystatins) of Human, Mammal, and Parasite Origin

Acta Chimica Slovenica, 2019
The majority of lysosomal cysteine cathepsins are ubiquitously expressed enzymes. However, some of them differ in their specific cell or tissue distribution and substrate specificity, suggesting their involvement in determining normal cellular processes,
Vito Turk, Dušan Turk, Iztok Dolenc, Veronika Stoka   +3 more
doaj   +1 more source

Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification [PDF]

, 2016
Filamentation induced by cyclic AMP (FIC)-domain enzymes catalyze adenylylation or other posttranslational modifications of target proteins to control their function.
Aragão, Hugo, Burmann, Björn M., Dehio, Christoph, Harms, Alexander, Hiller, Sebastian, Mazur, Adam, Schirmer, Tilman, Sharpe, Timothy, Stanger, Frédéric V.   +8 more
core   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

Advanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda, Ada Bernaus Vives, Michał Wojciechowski, Dinh Quoc Huy Pham, Mateusz Chwastyk, Mario Vallejo, Anna Novials, Douglas V. Laurents, Mariano Carrión‐Vázquez   +8 more
wiley   +1 more source

Identification of Oligomerizing Peptides [PDF]

Journal of Biological Chemistry, 2001
The AraC DNA binding domain is inactive in a monomeric form but can activate transcription from the arabinose operon promoters upon its dimerization. We used this property to identify plasmids encoding peptide additions to the AraC DNA binding domain that could dimerize the domain.
A, Dhiman, M E, Rodgers, R, Schleif
openaire   +2 more sources

Domain interactions within Fzo1 oligomers are essential for mitochondrial fusion [PDF]

, 2006
Mitofusins are conserved GTPases essential for the fusion of mitochondria. These mitochondrial outer membrane proteins contain a GTPase domain and two or three regions with hydrophobic heptad repeats, but little is known about how these domains interact ...
Chan, David C., Griffin, Erik E.
core   +3 more sources