Results 101 to 110 of about 708,274 (274)

Simultaneous Qualitative And Quantitative Identification Of Multiple Targets By Polymerase Chain Reaction On Microarray [PDF]

Chapter 12 at "Oligonucleotide Array Sequence Analysis", Nova Publishers, ISBN: 978-1-60456-542-3, 2008
An approach for multiplex qualitative and quantitative microarray-based PCR analysis has been proposed. The characteristics of PCR executed on a gel-based oligonucleotide microarray with immobilized forward primers and a single common reverse primer in solution were investigated for several DNA targets.
arxiv  

Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate regulation

BMC Bioinformatics, 2008
Background Gene expression measurements from breast cancer (BrCa) tumors are established clinical predictive tools to identify tumor subtypes, identify patients showing poor/good prognosis, and identify patients likely to have disease recurrence. However,
Lundberg Cathryn, Snøve Ola, Sætrom Pål, Smith David D, Rivas Guillermo E, Glackin Carlotta, Larson Garrett P   +6 more
doaj   +1 more source

Copy number variations analysis in a cohort of 47 fetuses and newborns with congenital diaphragmatic hernia

Prenatal Diagnosis, Volume 42, Issue 13, Page 1627-1635, December 2022., 2022
Abstract Objectives The congenital diaphragmatic hernia (CDH), characterized by malformation of the diaphragm and lung hypoplasia, is a common and severe birth defect that affects around 1 in 4000 live births. However, the etiology of most cases of CDH remains unclear.
Marie Boisson, Anne‐Gael Cordier, Jelena Martinovic, Aline Receveur, Aurélie Mouka, Romain Diot, Catherine Egoroff, Geoffroy Esnault, Loïc Drévillon, Alexandra Benachi, Gérard Tachdjian, Lucie Tosca   +11 more
wiley   +1 more source

From features to expression: High-density oligonucleotide array analysis revisited [PDF]

arXiv, 2001
One of the most popular tools for large scale gene expression studies are high-density oligonucleotide (GeneChip(R)) arrays. These currently have 16-20 small probe cells (``features'') for evaluating the transcript abundance of each gene. In addition, each probe is accompanied by a mismatched probe designed as a control for non-specificity.
arxiv  

Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: A biomarker for the early detection of cancer

Molecular Cancer, 2006
Background Somatic mutations of mitochondrial DNA (mtDNA) are common in many human cancers. We have described an oligonucleotide microarray ("MitoChip") for rapid sequencing of the entire mitochondrial genome (Zhou et al, J Mol Diagn 2006), facilitating ...
Montgomery Elizabeth A, Eshleman James R, Lee Edward E, Canto Marcia, Wang Jean, Zhou Shaoyu, Sui Guoping, Sidransky David, Califano Joseph A, Maitra Anirban   +9 more
doaj   +1 more source

MIMAS 3.0 is a Multiomics Information Management and Annotation System

BMC Bioinformatics, 2009
Background DNA sequence integrity, mRNA concentrations and protein-DNA interactions have been subject to genome-wide analyses based on microarrays with ever increasing efficiency and reliability over the past fifteen years.
Rougemont Jacques, Collin Olivier, Xenarios Ioannis, Liechti Robin, Hermida Leandro, Gattiker Alexandre, Primig Michael   +6 more
doaj   +1 more source

Carcinoma de mama: novos conceitos na classificação Breast cancer: new concepts in classification

Revista Brasileira de Ginecologia e Obstetrícia, 2008
O carcinoma de mama é a neoplasia maligna mais comum em mulheres. Estudos moleculares do carcinoma de mama, baseados na identificação do perfil de expressão gênica por meio do cDNA microarray, permitiram definir pelo menos cinco sub-grupos distintos ...
Daniella Serafin Couto Vieira, Rozany Mucha Dufloth, Fernando Carlos Lander Schmitt, Luiz Carlos Zeferino   +3 more
doaj   +1 more source

Structural and functional-annotation of an equine whole genome oligoarray

BMC Bioinformatics, 2009
Background The horse genome is sequenced, allowing equine researchers to use high-throughput functional genomics platforms such as microarrays; next-generation sequencing for gene expression and proteomics.
Chowdhary Bhanu, Burgess Shane C, Bright Lauren A, Swiderski Cyprianna E, McCarthy Fiona M   +4 more
doaj   +1 more source

Genome-wide mapping of ORC and Mcm2p binding sites on tiling arrays and identification of essential ARS consensus sequences in S. cerevisiae

BMC Genomics, 2006
Background Eukaryotic replication origins exhibit different initiation efficiencies and activation times within S-phase. Although local chromatin structure and function influences origin activity, the exact mechanisms remain poorly understood.
Aparicio Oscar M, Aparicio Jennifer G, Xu Weihong, Tavaré Simon   +3 more
doaj   +1 more source

Selection of DNA Aptamers Against Parathyroid Hormone for Electrochemical Impedimetric Biosensor System Development

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT This work presents the pioneering development of an aptamer‐based electrochemical biosensor for real‐time monitoring of parathyroid hormone (PTH) levels, with a focus on intraoperative assessment during parathyroid surgery. It introduces, for the first time, the selection and characterization of aptamers targeting distinct segments of the PTH ...
Reza Didarian, Saharnaz Bargh, Almina Gülerman, Veli Cengiz Özalp, Özcan Erel, Nimet Yildirim‐Tirgil   +5 more
wiley   +1 more source