Results 161 to 170 of about 130,578 (251)

Microallopatric Speciation in Southern African Dung Beetle Genus Macroderes Driven by Miocene Aridification and Ancestral Flight Loss

Journal of Biogeography, EarlyView.
ABSTRACT Aim Southern Africa harbours a diverse array of dung beetles (Scarabaeidae: Scarabaeinae), with many species endemic to the region. Despite this diversity, the historical drivers of their evolution remain largely unexplored. This study investigates the evolutionary history of the flightless dung beetle genus Macroderes, testing its monophyly ...
Gimo M. Daniel, Ishtiag H. Abdalla, Clarke H. Scholtz, Catherine L. Sole   +3 more
wiley   +1 more source

First description of co-occurrence of 49,XXXXY and X-linked Cornelia de Lange syndrome: case report. [PDF]

Front Endocrinol (Lausanne)
Al-Rashdi S, Ekstrom L, Collins A, Schulz HL, Dinwiddie A, Samango-Sprouse C, Olaya M, Moser E, Green AJ.   +8 more
europepmc   +1 more source

Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder

Journal of Internal Medicine, EarlyView.
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley   +1 more source

Mitochondrial mRNA oligocitydylation occurs in Chlorophyceae and Ulvales but not Bryopsidales or Trebouxiophyceae. [PDF]

J Phycol
Cahoon AB, Maggard IJ, Pathan WN.
europepmc   +1 more source

Loss of E3 ligase HvST1 function substantially increases distal crossover frequency

New Phytologist, EarlyView.
Summary This study characterizes the function of a grass‐specific E3 ubiquitin ligase, HvST1, in regulating synapsis and crossover (CO) formation during meiosis in barley (Hordeum vulgare). In large‐genome cereals, COs are predominantly restricted to distal chromosomal regions, limiting genetic recombination and breeding flexibility.
Jamie Neil Orr, Sybille Ursula Mittmann, Luke Ramsay, Dominika Lewandowska, Abdellah Barakate, Malcolm Macaulay, Nicola McCallum, Robbie Waugh, Isabelle Colas   +8 more
wiley   +1 more source

Diversity in Carbapenemases in Enterobacterales in Southeastern Austria Before and During the COVID-19 Pandemic. [PDF]

Pathogens
Grisold A, Gruber L, Mandl Y, Luxner J, Bedenić B, Zarfel G.   +5 more
europepmc   +1 more source

Expanded Functional Characterization and Optimization of Protein Expression in Treponema denticola Shuttle Plasmids

Molecular Oral Microbiology, EarlyView.
We report optimization of the Treponema denticola shuttle plasmid system by minimizing its size and by characterizing an array of promoter‐gene constructs for genetic complementation, including the first use in Treponema of a Tet‐inducible system for controlled expression of potentially toxic genes.
M. Paula Goetting‐Minesky, Valentina Godovikova, Prakaimuk Saraithong, Alexander H. Rickard, Brigette R. Crawley, Sara M. Agolli, Reagan L. Boyce, Trishna L. Appaji, J. Christopher Fenno   +8 more
wiley   +1 more source

Tissular chromatin-state cartography based on double-barcoded DNA arrays that capture unloaded PA-Tn5 transposase. [PDF]

Genome Res
Mendoza-Ferri MG, Lozachmeur G, Duvina M, Perret L, Merciris D, Gigout A, Mendoza-Parra MA.   +6 more
europepmc   +1 more source

Complex engineering of Solanum alkaloids structural diversity in Nicotiana benthamiana

Plant Biotechnology Journal, EarlyView.
Summary Transient expression in Nicotiana benthamiana offers a powerful and versatile platform for rapid production of complex specialized metabolites. Steroidal glycoalkaloids (SGAs) and steroidal saponins produced by members of the Solanaceae family are known for their diverse structures and activities including antimicrobial, anticancer, antiviral ...
Sachin A. Gharat, Adam Jozwiak, Ilana Rogachev, Elinor A. Sharon, Sagit Meir, Ashok P. Giri, Asaph Aharoni   +6 more
wiley   +1 more source

High-throughput DNA melt measurements enable improved models of DNA folding thermodynamics. [PDF]

Nat Commun
Ke Y, Sharma E, Wayment-Steele HK, Becker WR, Ho A, Marklund E, Greenleaf WJ.   +6 more
europepmc   +1 more source