Results 201 to 210 of about 708,274 (274)

Engineering Base Changes and Epitope-Tagged Alleles in Mice Using Cas9 RNA-Guided Nuclease. [PDF]

Curr Protoc
Gertsenstein M, Lintott LG, Nutter LMJ.
europepmc   +1 more source

High-accuracy crRNA array assembly strategy for multiplex CRISPR. [PDF]

Mol Ther Nucleic Acids
Zhao X, Yang L, Li P, Cheng Z, Jia Y, Luo L, Bi A, Xiong H, Zhang H, Xu H, Zhang J, Zhang Y.   +11 more
europepmc   +1 more source

Genetic Mapping by 55K Single-Nucleotide Polymorphism Array Reveals Candidate Genes for Tillering Trait in Wheat Mutant dmc. [PDF]

Genes (Basel)
Jiao K, Xia G, Zhou Y, Zhao C, Yan H, Qi M, Xie P, Ni Y, Zhao J, Niu J, Chao Z, Ren J, Li L.   +12 more
europepmc   +1 more source

The Human‐Specific miR‐6762‐5p Is an Activator of RhoA GTPase Enhancing Shigella flexneri Intercellular Spreading

Molecular Microbiology, EarlyView.
Proposed model in which human miR‐6762‐5p expression activates RhoA to promote Shigella flexneri dissemination: During the late phase of infection, miR‐6762‐5p is expressed from its host gene TPCN1. This leads to RhoA activation and thus stress fiber formation.
Caroline Reisacher, Estelle Saifi, Elisabeth Ageron, Robert Theodor Mallmann, Norbert Klugbauer, David Skurnik, Laurence Arbibe   +6 more
wiley   +1 more source

Oligonucleotide Therapies for Facioscapulohumeral Muscular Dystrophy: Current Preclinical Landscape. [PDF]

Int J Mol Sci
Beck SL, Yokota T.
europepmc   +1 more source

Protein Homeostasis Impairment Alters Phenotypic Heterogeneity of Biofilm Communities

Molecular Microbiology, EarlyView.
In biofilms, genetically identical cells exhibit diverse gene expression, resulting in subpopulations of functionally distinct and coexisting cell types, such as motile cells, extracellular matrix producers, and spores. Balanced phenotypic heterogeneity produces robust biofilms.
Judith Matavacas, Claes von Wachenfeldt
wiley   +1 more source

A universal method for the purification of C2H2 zinc finger arrays. [PDF]

PLoS One
Liang J, Azubel M, Wang G, Nie Y, Kornberg RD, Beel AJ, Mattei PJ.   +6 more
europepmc   +1 more source

Integrative omics reveals mechanisms of biosynthesis and regulation of floral scent in Cymbidium tracyanum

Plant Biotechnology Journal, EarlyView.
Summary Flower scent is a crucial determiner in pollinator attraction and a significant horticultural trait in ornamental plants. Orchids, which have long been of interest in evolutionary biology and horticulture, exhibit remarkable diversity in floral scent type and intensity. However, the mechanisms underlying floral scent biosynthesis and regulation
Mengling Tu, Ningyawen Liu, Zheng‐Shan He, Xiu‐Mei Dong, Tian‐Yang Gao, Andan Zhu, Jun‐Bo Yang, Shi‐Bao Zhang   +7 more
wiley   +1 more source

Adaptive immunity of type VI CRISPR-Cas systems associated with reverse transcriptase-Cas1 fusion proteins. [PDF]

Nucleic Acids Res
Molina-Sánchez MD, Martínez-Abarca F, Millán V, Mestre MR, Stehantsev P, Stetsenko A, Guskov A, Toro N.   +7 more
europepmc   +1 more source

Genome-Wide Tool for Sensitive de novo Identification and Visualisation of Interspersed and Tandem Repeats. [PDF]

Bioinform Biol Insights
Kalendar R, Kairov U.
europepmc   +1 more source