Microarray-based ultra-high resolution discovery of genomic deletion mutations [PDF]
, 2014 BACKGROUND: Oligonucleotide microarray-based comparative genomic hybridization (CGH) offers an attractive possible route for the rapid and cost-effective genome-wide discovery of deletion mutations.
Baban, D. +8 more
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Optimising the analysis of transcript data using high density oligonucleotide arrays and genomic DNA-based probe selection [PDF]
, 2007 Background: Affymetrix GeneChip arrays are widely used for transcriptomic studies in a diverse range of species. Each gene is represented on a GeneChip array by a probe-set, consisting of up to 16 probe-pairs. Signal intensities across probe-pairs within
Broadley, Martin R. +4 more
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Detection of minority variants within bovine respiratory syncytial virus populations using oligonucleotide-based microarrays [PDF]
, 2008 Microarray technology, originally developed for highly parallel examination of gene expression is regarded as a potential tool in prognosis and diagnosis.
Baranowski, Eric +4 more
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BMC Genomics, 2007 Background High-density oligonucleotide arrays are widely used for analysis of genome-wide expression and genetic variation. Affymetrix GeneChips – common high-density oligonucleotide arrays – contain perfect match (PM) and mismatch (MM) probes generated
Kashiwagi Akiko +4 more
doaj +1 more source
Microarrays and infectious diseases: overview and perspectives [PDF]
Einstein (São Paulo), 2005 Disease investigation is evolving in the light of the human genomeavailability and the complete genome sequencing of several humanpathogens. Microarray technology is a revolutionary tool for elucidatingroles of genes in infectious diseases, shifting from
Patricia Severino
doaj
Combining gene expression data from different generations of oligonucleotide arrays
BMC Bioinformatics, 2004 Background One of the important challenges in microarray analysis is to take full advantage of previously accumulated data, both from one's own laboratory and from public repositories.
Kong Sek +3 more
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Design, validation and annotation of transcriptome-wide oligonucleotide probes for the oligochaete annelid Eisenia fetida. [PDF]
PLoS ONE, 2010 High density oligonucleotide probe arrays have increasingly become an important tool in genomics studies. In organisms with incomplete genome sequence, one strategy for oligo probe design is to reduce the number of unique probes that target every non ...
Ping Gong +3 more
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Linear model for fast background subtraction in oligonucleotide microarrays [PDF]
, 2009 One important preprocessing step in the analysis of microarray data is background subtraction. In high-density oligonucleotide arrays this is recognized as a crucial step for the global performance of the data analysis from raw intensities to expression ...
Barkema, Gerard T. +2 more
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Efficient oligonucleotide probe selection for pan-genomic tiling arrays
BMC Bioinformatics, 2009 Background Array comparative genomic hybridization is a fast and cost-effective method for detecting, genotyping, and comparing the genomic sequence of unknown bacterial isolates.
Zhang Wei +3 more
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Clinical application of high throughput molecular screening techniques for pharmacogenomics. [PDF]
, 2011 Genetic analysis is one of the fastest-growing areas of clinical diagnostics. Fortunately, as our knowledge of clinically relevant genetic variants rapidly expands, so does our ability to detect these variants in patient samples.
Schrijver, Iris, Wiita, Arun P
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