Results 21 to 30 of about 740,905 (276)

Microarray generation of thousand-member oligonucleotide libraries. [PDF]

open access: yesPLoS ONE, 2011
The ability to efficiently and economically generate libraries of defined pieces of DNA would have a myriad of applications, not least in the area of defined or directed sequencing and synthetic biology, but also in applications associated with encoding ...
Nina Svensen   +2 more
doaj   +1 more source

Application of COMPOCHIP Microarray to Investigate the Bacterial Communities of Different Composts [PDF]

open access: yes, 2009
A microarray spotted with 369 different 16S rRNA gene probes specific to microorganisms involved in the degradation process of organic waste during composting was developed. The microarray was tested with pure cultures, and of the 30,258 individual probe-
A Alfreider   +54 more
core   +1 more source

Analysis of oligonucleotide array experiments with repeated measures using mixed models

open access: yesBMC Bioinformatics, 2004
Background Two or more factor mixed factorial experiments are becoming increasingly common in microarray data analysis. In this case study, the two factors are presence (Patients with Alzheimer's disease) or absence (Control) of the disease, and brain ...
Getchell Thomas V   +4 more
doaj   +1 more source

In vitro identification and in silico utilization of interspecies sequence similarities using GeneChip(® )technology [PDF]

open access: yes, 2005
BACKGROUND: Genomic approaches in large animal models (canine, ovine etc) are challenging due to insufficient genomic information for these species and the lack of availability of corresponding microarray platforms. To address this problem, we speculated
Garcia, Joe GN   +5 more
core   +3 more sources

Watching the hands of the Arabidopsis biological clock [PDF]

open access: yes, 2001
Oligonucleotide and cDNA microarrays have been used to analyse the mRNA levels of 8,000 genes in Arabidopsis thaliana throughout the day/night cycle. Genes involved in signal transduction and in various metabolic pathways were found to be coordinately ...
Davis, Seth J.   +1 more
core   +2 more sources

Experimental optimization of probe length to increase the sequence specificity of high-density oligonucleotide microarrays

open access: yesBMC Genomics, 2007
Background High-density oligonucleotide arrays are widely used for analysis of genome-wide expression and genetic variation. Affymetrix GeneChips – common high-density oligonucleotide arrays – contain perfect match (PM) and mismatch (MM) probes generated
Kashiwagi Akiko   +4 more
doaj   +1 more source

Microarrays and infectious diseases: overview and perspectives [PDF]

open access: yesEinstein (São Paulo), 2005
Disease investigation is evolving in the light of the human genomeavailability and the complete genome sequencing of several humanpathogens. Microarray technology is a revolutionary tool for elucidatingroles of genes in infectious diseases, shifting from
Patricia Severino
doaj  

Combining gene expression data from different generations of oligonucleotide arrays

open access: yesBMC Bioinformatics, 2004
Background One of the important challenges in microarray analysis is to take full advantage of previously accumulated data, both from one's own laboratory and from public repositories.
Kong Sek   +3 more
doaj   +1 more source

Design, validation and annotation of transcriptome-wide oligonucleotide probes for the oligochaete annelid Eisenia fetida. [PDF]

open access: yesPLoS ONE, 2010
High density oligonucleotide probe arrays have increasingly become an important tool in genomics studies. In organisms with incomplete genome sequence, one strategy for oligo probe design is to reduce the number of unique probes that target every non ...
Ping Gong   +3 more
doaj   +1 more source

A microfluidic oligonucleotide synthesizer [PDF]

open access: yes, 2010
De novo gene and genome synthesis enables the design of any sequence without the requirement of a pre-existing template as in traditional genetic engineering methods.
Lee, Cheng-Chung   +2 more
core   +4 more sources

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