Results 31 to 40 of about 131,505 (250)
Journal of Translational Medicine, 2003 Detection of unknown single nucleotide polymorphism (SNP) relies on large scale sequencing expeditions of genomic fragments or complex high-throughput chip technology.
Klein Harvey +6 more
doaj +1 more source
In vitro identification and in silico utilization of interspecies sequence similarities using GeneChip(® )technology [PDF]
, 2005 BACKGROUND: Genomic approaches in large animal models (canine, ovine etc) are challenging due to insufficient genomic information for these species and the lack of availability of corresponding microarray platforms. To address this problem, we speculated
Garcia, Joe GN +5 more
core +3 more sources
BMC Genomics, 2006 Background There are many potential sources of variability in a microarray experiment. Variation can arise from many aspects of the collection and processing of samples for gene expression analysis.
Enkemann Steven A +2 more
doaj +1 more source
Conformational profiling of a G-rich sequence within the c-KIT promoter [PDF]
, 2017 G-quadruplexes (G4) within oncogene promoters are considered to be promising anticancer targets. However, often they undergo complex structural rearrangements that preclude a precise description of the optimal target.
Chaires, Jonathan B +4 more
core +1 more source
DNA microarrays in cancer diagnosis and prognosis [PDF]
Einstein (São Paulo), 2005 This review discusses recent advances in our understanding ofthe human genome and the application of derived technologies inthe medical area. It focuses on the use of DNA microarray fordiagnosis, prognosis, and therapeutic purposes in oncology, andthe ...
Oswaldo Keith Okamoto
doaj
Design and evaluation of Actichip, a thematic microarray for the study of the actin cytoskeleton
BMC Genomics, 2007 Background The actin cytoskeleton plays a crucial role in supporting and regulating numerous cellular processes. Mutations or alterations in the expression levels affecting the actin cytoskeleton system or related regulatory mechanisms are often ...
Chalmel Frédéric +8 more
doaj +1 more source
G-spots cause incorrect expression measurement in Affymetrix microarrays [PDF]
, 2008 Background High Density Oligonucleotide arrays (HDONAs), such as the Affymetrix HG-U133A GeneChip, use sets of probes chosen to match specified genes, with the expectation that if a particular gene is highly expressed then all the probes in ...
Harrison, Andrew P +2 more
core +2 more sources
BMC Genomics, 2006 Background DNA microarrays have proven powerful for functional genomics studies. Several technologies exist for the generation of whole-genome arrays.
Fairbanks Benjamin D +4 more
doaj +1 more source
Advancing transcriptome platforms [PDF]
, 2011 During the last decade of years, remarkable technological innovations have emerged that allow the direct or indirect determination of the transcriptome at unprecedented scale and speed.
Shuobo Shi
core +2 more sources
Secondary structure in the target as a confounding factor in synthetic oligomer microarray design
BMC Genomics, 2005 Background Secondary structure in the target is a property not usually considered in software applications for design of optimal custom oligonucleotide probes.
Gibas Cynthia J +2 more
doaj +1 more source