Watching the hands of the Arabidopsis biological clock [PDF]
, 2001 Oligonucleotide and cDNA microarrays have been used to analyse the mRNA levels of 8,000 genes in Arabidopsis thaliana throughout the day/night cycle. Genes involved in signal transduction and in various metabolic pathways were found to be coordinately ...
Davis, Seth J. +1 more
core +2 more sources
Simultaneous genotyping and species identification using hybridization pattern recognition analysis of generic Mycobacterium DNA arrays [PDF]
, 1998 High-density oligonucleotide arrays can be used to rapidly examine large amounts of DNA sequence in a high throughput manner. An array designed to determine the specific nucleotide sequence of 705 bp of the rpoB gene of Mycobacterium tuberculosis ...
Alland, D. +9 more
core +1 more source
Oligonucleotide Array for Mutation Analysis in Familial Breast Cancer
Disease Markers, 2002 Detecting recurrent mutations in the BRCA1 and BRCA2 genes presents a challenge because these mutations are scattered throughout each of the genes.
A. Metspalu +3 more
semanticscholar +1 more source
In vitro identification and in silico utilization of interspecies sequence similarities using GeneChip(® )technology [PDF]
, 2005 BACKGROUND: Genomic approaches in large animal models (canine, ovine etc) are challenging due to insufficient genomic information for these species and the lack of availability of corresponding microarray platforms. To address this problem, we speculated
Garcia, Joe GN +5 more
core +3 more sources
Design, validation and annotation of transcriptome-wide oligonucleotide probes for the oligochaete annelid Eisenia fetida. [PDF]
PLoS ONE, 2010 High density oligonucleotide probe arrays have increasingly become an important tool in genomics studies. In organisms with incomplete genome sequence, one strategy for oligo probe design is to reduce the number of unique probes that target every non ...
Ping Gong +3 more
doaj +1 more source
Linear model for fast background subtraction in oligonucleotide microarrays [PDF]
, 2009 One important preprocessing step in the analysis of microarray data is background subtraction. In high-density oligonucleotide arrays this is recognized as a crucial step for the global performance of the data analysis from raw intensities to expression ...
Barkema, Gerard T. +2 more
core +4 more sources
Microarrays and infectious diseases: overview and perspectives [PDF]
Einstein (São Paulo), 2005 Disease investigation is evolving in the light of the human genomeavailability and the complete genome sequencing of several humanpathogens. Microarray technology is a revolutionary tool for elucidatingroles of genes in infectious diseases, shifting from
Patricia Severino
doaj
Combining gene expression data from different generations of oligonucleotide arrays
BMC Bioinformatics, 2004 Background One of the important challenges in microarray analysis is to take full advantage of previously accumulated data, both from one's own laboratory and from public repositories.
Kong Sek +3 more
doaj +1 more source
Optimising the analysis of transcript data using high density oligonucleotide arrays and genomic DNA-based probe selection [PDF]
, 2007 Background: Affymetrix GeneChip arrays are widely used for transcriptomic studies in a diverse range of species. Each gene is represented on a GeneChip array by a probe-set, consisting of up to 16 probe-pairs. Signal intensities across probe-pairs within
Broadley, Martin R. +4 more
core +4 more sources
Efficient oligonucleotide probe selection for pan-genomic tiling arrays
BMC Bioinformatics, 2009 Background Array comparative genomic hybridization is a fast and cost-effective method for detecting, genotyping, and comparing the genomic sequence of unknown bacterial isolates.
Zhang Wei +3 more
doaj +1 more source