Results 31 to 40 of about 129,877 (153)

Detection of minority variants within bovine respiratory syncytial virus populations using oligonucleotide-based microarrays [PDF]

, 2008
Microarray technology, originally developed for highly parallel examination of gene expression is regarded as a potential tool in prognosis and diagnosis.
Baranowski, Eric, Deplanche, Martine, François, Jean Marie, Leberre, Véronique, Trouilh, Lidwine   +4 more
core   +2 more sources

A strategy for detection of known and unknown SNP using a minimum number of oligonucleotides applicable in the clinical settings

Journal of Translational Medicine, 2003
Detection of unknown single nucleotide polymorphism (SNP) relies on large scale sequencing expeditions of genomic fragments or complex high-throughput chip technology.
Klein Harvey, Simon Richard, Panelli Monica, Zhao Yingdong, Adams Sharon, Wang Ena, Marincola Francesco M   +6 more
doaj   +1 more source

Identical probes on different high-density oligonucleotide microarrays can produce different measurements of gene expression

BMC Genomics, 2006
Background There are many potential sources of variability in a microarray experiment. Variation can arise from many aspects of the collection and processing of samples for gene expression analysis.
Enkemann Steven A, Yoder Sean J, Zhang LanMin   +2 more
doaj   +1 more source

Advancing transcriptome platforms [PDF]

, 2011
During the last decade of years, remarkable technological innovations have emerged that allow the direct or indirect determination of the transcriptome at unprecedented scale and speed.
Shuobo Shi
core   +2 more sources

Design and evaluation of Actichip, a thematic microarray for the study of the actin cytoskeleton

BMC Genomics, 2007
Background The actin cytoskeleton plays a crucial role in supporting and regulating numerous cellular processes. Mutations or alterations in the expression levels affecting the actin cytoskeleton system or related regulatory mechanisms are often ...
Chalmel Frédéric, Muller Arnaud, Yatskou Mikalai, Vetter Guillaume, Mehlen André, Muller Jean, Poch Olivier, Friederich Evelyne, Vallar Laurent   +8 more
doaj   +1 more source

A cellulose-based bioassay for the colorimetric detection of pathogen DNA [PDF]

, 2014
Cellulose-paper-based colorimetric bioassays may be used at the point of sampling without sophisticated equipment. This study reports the development of a colorimetric bioassay based on cellulose that can detect pathogen DNA.
Goyal, Madhu, Kukol, A., Rossiter, Sharon, Saikrishnan, Deepika   +3 more
core   +1 more source

DNA microarrays in cancer diagnosis and prognosis [PDF]

Einstein (São Paulo), 2005
This review discusses recent advances in our understanding ofthe human genome and the application of derived technologies inthe medical area. It focuses on the use of DNA microarray fordiagnosis, prognosis, and therapeutic purposes in oncology, andthe ...
Oswaldo Keith Okamoto
doaj  

A comparison of alternative 60-mer probe designs in an in-situ synthesized oligonucleotide microarray

BMC Genomics, 2006
Background DNA microarrays have proven powerful for functional genomics studies. Several technologies exist for the generation of whole-genome arrays.
Fairbanks Benjamin D, Hume Patrick S, Karimpour-Fard Anis, Leiske Danielle L, Gill Ryan T   +4 more
doaj   +1 more source

NOTCH2 is neither rearranged nor mutated in t(1;19) positive oligodendrogliomas. [PDF]

PLoS ONE, 2009
The combined deletion of 1p and 19q chromosomal arms is frequent in oligodendrogliomas (OD) and has recently been shown to be mediated by an unbalanced t(1;19) translocation.
Magdalena Benetkiewicz, Ahmed Idbaih, Pierre-Yves Cousin, Blandine Boisselier, Yannick Marie, Emmanuelle Crinière, Khê Hoang-Xuan, Jean-Yves Delattre, Marc Sanson, Olivier Delattre   +9 more
doaj   +1 more source

Normalized Affymetrix expression data are biased by G-quadruplex formation [PDF]

, 2011
Probes with runs of four or more guanines (G-stacks) in their sequences can exhibit a level of hybridization that is unrelated to the expression levels of the mRNA that they are intended to measure.
Altman, Andrew P. Harrison, Barrett, Bolstad, Burge, Cambon, Do, Dudoit, Eisen, Farhat N. Memon, Geller, Gellert, Giorgi, Graham J. G. Upton, Hammond, Harris, Hochreiter, Hubbell, Hugh P. Shanahan, Irizarry, Irizarry, Iwamoto, Kittleson, Langdon, Li, Memon, Memon, Naef, Patterson, Ringnér, Ryan, Sen, Stalteri, Upton, Upton, Walton, Wu   +36 more
core   +3 more sources