Results 31 to 40 of about 740,905 (276)

Efficient oligonucleotide probe selection for pan-genomic tiling arrays

BMC Bioinformatics, 2009
Background Array comparative genomic hybridization is a fast and cost-effective method for detecting, genotyping, and comparing the genomic sequence of unknown bacterial isolates.
Zhang Wei, Deng Xiangyu, Phillippy Adam M, Salzberg Steven L   +3 more
doaj   +1 more source

Real-time DNA microarray analysis [PDF]

, 2009
We present a quantification method for affinity-based DNA microarrays which is based on the real-time measurements of hybridization kinetics. This method, i.e.
Abdueva, Arjang Hassibi, Babak Hassibi, Bassil, Beissbarth, Belosludtsev, Berg, Bishop, Chee, Chen, Dai, Das, Fritz, Georgiadis, Ghosh, Hall, Hardenbol, Haris Vikalo, Hassibi, Hassibi, Hassibi, Heaton, Homola, Hubble, Huber, José Luis Riechmann, Kennedy, Lacowicz, Levine, Linneti, Lockhart, Lockhart, Marras, Okamura, Ota, Pease, Peterson, Rajendran, SantaLucia, Savran, Schena, Schena, Schienle, Shalon, Skvortsov, Smith, Steinfield, Stimpson, Su, Towery, Tu, Van Kampen, Vikalo, Wang, Watterson, Yamaguchi, Zeng   +56 more
core   +3 more sources

Identification of genomic imbalances in oral clefts

Jornal de Pediatria, 2021
Objective: This article presents a clinical and cytogenomic approach that focuses on the diagnosis of syndromic oral clefts (OCs). Methods: The inclusion criteria were individuals with OC presenting four or more minor signs and no major defects (non ...
Elaine Lustosa-Mendes, Ana P. dos Santos, Társis P. Vieira, Erlane M. Ribeiro, Adriana A. Rezende, Agnes C. Fett-Conte, Denise P. Cavalcanti, Têmis M. Félix, Isabella L. Monlleó, Vera Lúcia Gil-da-Silva-Lopes   +9 more
doaj  

A strategy for detection of known and unknown SNP using a minimum number of oligonucleotides applicable in the clinical settings

Journal of Translational Medicine, 2003
Detection of unknown single nucleotide polymorphism (SNP) relies on large scale sequencing expeditions of genomic fragments or complex high-throughput chip technology.
Klein Harvey, Simon Richard, Panelli Monica, Zhao Yingdong, Adams Sharon, Wang Ena, Marincola Francesco M   +6 more
doaj   +1 more source

Identical probes on different high-density oligonucleotide microarrays can produce different measurements of gene expression

BMC Genomics, 2006
Background There are many potential sources of variability in a microarray experiment. Variation can arise from many aspects of the collection and processing of samples for gene expression analysis.
Enkemann Steven A, Yoder Sean J, Zhang LanMin   +2 more
doaj   +1 more source

Using genomic DNA-based probe-selection to improve the sensitivity of high-density oligonucleotide arrays when applied to heterologous species [PDF]

, 2005
High-density oligonucleotide (oligo) arrays are a powerful tool for transcript profiling. Arrays based on GeneChip® technology are amongst the most widely used, although GeneChip® arrays are currently available for only a small number of plant and animal
Broadley, Martin R., Craigon, David J., Emmerson, Zoe F., Hammond, John P., Higgins, Janet, May, Sean T., Townsend, Henrik J., White, Philip J.   +7 more
core   +3 more sources

High sensitivity electrochemical DNA sensors for detection of somatic mutations in FFPE samples [PDF]

arXiv, 2022
We offer new high-performance label-free electrochemical impedimetric DNA sensors of non-faradaic type. The DNA sensors based on a platform of crystalline carbon nanotube (CNT) arrays are fabricated by the Langmuir--Blodgett (LB) deposition technique. The CNT arrays are suspended on a nanoporous anodic alumina (aluminium oxide, AOA) support.
arxiv  

Design and evaluation of Actichip, a thematic microarray for the study of the actin cytoskeleton

BMC Genomics, 2007
Background The actin cytoskeleton plays a crucial role in supporting and regulating numerous cellular processes. Mutations or alterations in the expression levels affecting the actin cytoskeleton system or related regulatory mechanisms are often ...
Chalmel Frédéric, Muller Arnaud, Yatskou Mikalai, Vetter Guillaume, Mehlen André, Muller Jean, Poch Olivier, Friederich Evelyne, Vallar Laurent   +8 more
doaj   +1 more source

Optimising the analysis of transcript data using high density oligonucleotide arrays and genomic DNA-based probe selection [PDF]

, 2007
Background: Affymetrix GeneChip arrays are widely used for transcriptomic studies in a diverse range of species. Each gene is represented on a GeneChip array by a probe-set, consisting of up to 16 probe-pairs. Signal intensities across probe-pairs within
Broadley, Martin R., Graham, Neil S., Hammond, John P., May, Sean T., White, Philip J.   +4 more
core   +4 more sources

MicroRNA Expression Profiling by Bead Array Technology in Human Tumor Cell Lines Treated with Interferon-Alpha-2a

Biological Procedures Online, 2009
MicroRNAs are positive and negative regulators of eukaryotic gene expression that modulate transcript abundance by specific binding to sequence motifs located prevalently in the 3' untranslated regions of target messenger RNAs (mRNA). Interferon-alpha-2a
Siegrist Fredy, Singer Thomas, Certa Ulrich   +2 more
doaj   +3 more sources