Results 211 to 220 of about 119,501 (270)

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

Potential antisense oligonucleotide targeting LINC00673 on proliferation and apoptosis in tongue squamous cell carcinoma. [PDF]

J Taibah Univ Med Sci
Wibawa KGP, Supriatno, Handajani J.
europepmc   +1 more source

Beyond lipids: Systemic effects of lipoprotein apheresis

Transfusion, EarlyView.
Menatalla Nadim, Yamac Akgun
wiley   +1 more source

A Systematic Review and Model‐Based Meta‐Analysis of Pegylated‐Interferon‐α‐Induced HBsAg Loss in Chronic Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Pegylated‐interferon‐α (Peg‐IFNα) is a treatment option for chronic hepatitis B virus (HBV) infection. To quantify treatment response variability, we conducted a model‐based meta‐analysis (MBMA) of hepatitis B surface antigen (HBsAg) loss, defined as a binary outcome based on HBsAg levels falling below the limit of detection, with Peg‐IFNα ...
Nathan J. Hanan, Matthew L. Zierhut, Ahmed Nader, Anadi Mahajan, Amandeep Kaur, Krishna Kumar, Susan A. Dixon, Joyeta Das, Mindy Magee, Dickens Theodore, Vera Gielen   +10 more
wiley   +1 more source

Nanomedicine-driven microRNA therapy: a precision approach for eosinophilic granulomatosis with polyangiitis. [PDF]

Ann Med Surg (Lond)
Imran G, Kumari A, Khalid M, Talha M, Waafira A.   +4 more
europepmc   +1 more source

MSC‐Derived Exosomal lnc‐AGT‐3: A Novel Anti‐Angiogenic Target in Age‐Related Macular Degeneration Through p53 Signaling Pathway

Aging Cell, Volume 25, Issue 2, February 2026.
MSC‐derived exosomes deliver lnc‐AGT‐3 to vascular endothelial cells, where it binds hnRNP K in the nucleus. This interaction inhibits p53 ubiquitination, enhancing p53 stabilization and transcriptional activation of anti‐angiogenic targets TSP1. Consequently, p53‐mediated signaling is potentiated, effectively suppressing choroidal neovascularization ...
Lingjie Kong, Xiaoyan Han, Siyi Qi, Duo Li, Jingyue Zhang, Linyu Zhang, Shujie Zhang, Qin Jiang, Biao Yan, Chen Zhao   +9 more
wiley   +1 more source

Strand-specific detection of cell-associated sense and antisense HIV-1 RNAs in splenocytes and PBMC from PLWH. [PDF]

Retrovirology
Waast L, Geronimi A, Mélard A, Figueiredo S, Maisch M, Viard JP, Avettand-Fenoel V, Dutrieux J, Pique C.   +8 more
europepmc   +1 more source

LncRNA DANCR Activates p38/mTOR‐Mediated Autophagy via ANXA2 to Exacerbate Oxygen‐Induced Retinal Neovascularization in Mice

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
This study reveals that the long non‐coding RNA DANCR drives pathological retinal neovascularization in oxygen‐induced retinopathy via an ANXA2‐dependent p38/MAPK/mTOR autophagy pathway. In hypoxic endothelial cells and a murine OIR model, DANCR promotes angiogenesis.
Yini Wang, Jiale Bai, Shihong Zhao
wiley   +1 more source

Targeting rare splicing defects: Antisense oligonucleotides offer a therapeutic strategy in FRDA. [PDF]

Mol Ther Nucleic Acids
Kerkhof LMC, Buijsen RAM.
europepmc   +1 more source

Nanotherapy Targeting miR-10b Improves Survival in Orthotopic Glioblastoma Models. [PDF]

J Funct Biomater
Kim BD, Chen M, Mondal SK, Kenyon E, Mallett CL, deCarvalho A, Medarova Z, Moore A.   +7 more
europepmc   +1 more source