Results 221 to 230 of about 119,501 (270)

Biophysical and biological properties of splice-switching oligonucleotides and click conjugates containing LNA-phosphothiotriester linkages. [PDF]

Nucleic Acids Res
Dhara D, Hill AC, Ramesh A, Traore D, Radzikowska-Cieciura E, Wood MJA, Brown T.   +6 more
europepmc   +1 more source

Decoding retinitis pigmentosa: molecular targets and therapy with focus on pre-mRNA splicing. [PDF]

Cell Mol Life Sci
Banik P, Staněk D.
europepmc   +1 more source

A modified X10-23 DNAzyme that can better access large, structured RNA targets. [PDF]

Nucleic Acids Res
Nurmi C, Barber HM, Kaur H, Brennan JD, Damha MJ, Li Y.   +5 more
europepmc   +1 more source

Structural Characterization of <i>DDX23</i> 5' UTR Regulatory Elements and Their Targeting by LNA-Modified Antisense Oligonucleotides. [PDF]

Int J Mol Sci
Kamzeeva P, Shepelev N, Zabbarova V, Brylev V, Chistov A, Ryazantsev D, Kot E, Novopashina D, Rubtsova M, Aralov A.   +9 more
europepmc   +1 more source

Chemically inducible antisense oligonucleotides for cell-specific gene silencing. [PDF]

RSC Chem Biol
Xun Z, Hai Y, Tang LJ, Jiang JH, Wu Z.
europepmc   +1 more source

A cholesterol-responsive hepatic tRNA-derived small RNA regulates cholesterol homeostasis and atherosclerosis development. [PDF]

Nat Commun
Li X, Hernandez R, Zhang X, Tang S, Yuan X, Wu J, Pham K, Rawal HC, Heinrich EC, Zhang S, Chen Q, Zhou T, Zhou C.   +12 more
europepmc   +1 more source

Reversing the Irreversible: miRNA-Targeting Mesyl Phosphoramidate Oligonucleotides Restore Sensitivity to Cisplatin and Doxorubicin of KB-8-5 Epidermoid Carcinoma Cells. [PDF]

Biomedicines
Miroshnichenko S, Demirel R, Moralev A, Almieva O, Markov A, Burakova E, Stetsenko D, Maslov M, Vlassov V, Zenkova M.   +9 more
europepmc   +1 more source

Modeling and Simulation Identifies Endocytosis Uptake Rate and Fraction Unbound as Important Predictors of Oligonucleotide Pharmacokinetics. [PDF]

CPT Pharmacometrics Syst Pharmacol
Stader F, Derbalah A, Zyla A, Liu C, Gardner I, Sepp A.   +5 more
europepmc   +1 more source

HTLV-1 antisense transcription is promoted by increased SP1 binding at 3’-LTR G-Quadruplexes

Ruggiero E, Zanin I, Tosoni B, Richter SN.   +3 more
europepmc   +1 more source