Results 181 to 190 of about 414,656 (346)

AGAPIR: A Novel PIWI‐Interacting RNA Enhancing Post‐Decompression Angiogenesis in Degenerative Cervical Myelopathy

Advanced Science, EarlyView.
The restoration of blood flow following surgical decompression for degenerative cervical myelopathy (DCM) significantly contributes to the amelioration of neurological deficits. This study identifies AGAPIR, an angiogenesis‐associated PIWI‐interacting RNA, enhances angiogenesis and motor function recovery post‐spinal cord decompression in a mouse model
Yongheng Xie, Yiling Peng, Tianyu Qin, Cuimei Chen, Zhenxiao Ren, Naibo Feng, Chungeng Liu, Songlin Peng, Houqing Long   +8 more
wiley   +1 more source

General Approach for the Synthesis of Triazinyl Phosphoramidate Oligonucleotides via the Staudinger Reaction with the Use of 2‑Azido-4,6-dichloro-1,3,5-triazine. [PDF]

ACS Omega
Zharkov TD, Kupryushkin MS.
europepmc   +1 more source

Occurrence of Uridylate-Rich Oligonucleotide Regions in Heterogeneous Nuclear RNA of HeLa Cells

, 1972
George R. Molloy, William Thomas, James Darnell   +2 more
openalex   +1 more source

On the mechanism of oligonucleotide-primed RNA synthesis.I. Model studies with deoxy-homopolymer templates and Escherichia coli RNA polymerase [PDF]

, 1977
Coen F. van Kreijl, R.H.J. Beelen, Piet Borst   +2 more
openalex   +1 more source

PCSK9 Loss‐of‐Function Disrupts Cellular Microfilament Network via LIN28A/HES5/JMY Axis in Neural Tube Defects

Advanced Science, EarlyView.
PCSK9 acts as a molecular chaperone promoting LIN28A lysosomal degradation. LIN28A elevates transcription factor HES5, increasing JMY expression. PCSK9 loss causes neural tube defects (NTDs) by disrupting the LIN28A/HES5/JMY axis, and high JMY disorganizes the neural progenitor cell microfilament network, leading to incomplete neural tube structure in ...
Xiaoshuai Li, Rui Wang, Wenting Luo, Hui Gu, Tianchu Huang, Qiushi Wang, Zhengwei Yuan   +6 more
wiley   +1 more source

Physicochemical Properties of Phosphoramide <i>N</i>‑Benzimidazole Oligonucleotides in the Presence of Cosolvents. [PDF]

ACS Omega
Morozova FV, Kozyreva EA, Yushin II, Golyshev VM, Lomzov AA.   +4 more
europepmc   +1 more source

Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization.

PCR methods and applications, 1995
Genome Research, Kenneth J. Livak, Susan J.A. Flood, Jeffrey Marmaro, William Giusti, Karin Deetz   +5 more
semanticscholar   +1 more source

Addition of oligonucleotides to the 5′-terminus of DNA by T4 RNA ligase

, 1979
N. Patrick Higgins, Adam P. Geballe, Nicholas R. Cozzarelli   +2 more
openalex   +1 more source

NEAT1 Promotes Epileptogenesis in Tuberous Sclerosis Complex

Advanced Science, EarlyView.
The primary neurological manifestations of tuberous sclerosis complex (TSC) are intractable epilepsy and intellectual disability. NEAT1 is differentially expressed in TSC‐related epilepsy and influences neuronal excitability by regulating the PI3K/AKT/mTOR signaling pathway.
Suhui Kuang, Tinghong Liu, Zhirong Wei, Jinshan Xu, Jiayi Han, Jiaqi Wang, Feng Zhai, Yiran Tian, Shuli Liang   +8 more
wiley   +1 more source

Gene expression silencing therapy in tumors, focus on gastrointestinal and genitourinary tumors. [PDF]

Front Immunol
El-Ghazzi N, Italiano A, Angeli E.
europepmc   +1 more source