Results 221 to 230 of about 414,656 (346)

Effect of Cibacron blue F3GA on oligonucleotide binding site of estradiol--receptor complexes of mouse uterine cytosol.

, 1979
S. Anand Kumar, Thaisa A. Beach, Herbert W. Dickerman   +2 more
openalex   +1 more source

Macrophage Zc3h12c Limits Tissue Inflammation and Injury via Alternative Splicing of Pre‐mRNA

Advanced Science, EarlyView.
This work defines the context‐dependent function of Zc3h12c in macrophages using the Tnfrsf11a‐Cre system. It reveals Zc3h12c's dual mechanism—regulating RNA degradation and alternative splicing—with STAT1 as a key target. The findings elucidate a novel post‐transcriptional pathway and identify STAT1 isoforms as potential therapeutic targets for kidney
Chenyu Li, Julian Aurelio Marschner, Yoshihiro Kusunoki, Ningxin Zhang, Xiaoxin Li, Hao Deng, Zhibo Zhao, Kanako Watanabe‐Kusunoki, Zhihui Zhu, Yan Xu, Stefanie Steiger, Maciej Lech, Katalin Susztak, Christian Schulz, Hans‐Joachim Anders   +14 more
wiley   +1 more source

Therapeutic Oligonucleotides for Neurodegenerative Diseases: Aptamer Strategies and Clay Nanoparticle-Based Delivery. [PDF]

Chem Rec
Arciuolo V, D'Aria F, Caruso MR, Calvino MM, Amato J, Lazzara G, Milioto S, Giancola C, Cavallaro G, Pagano B.   +9 more
europepmc   +1 more source

Delivery of oligonucleotides with lipid nanoparticles.

Advanced Drug Delivery Reviews, 2015
Yuhua Wang, Lei Miao, A. Satterlee, Leaf Huang   +3 more
semanticscholar   +1 more source

Isolation of a cDNA clone for the human HLA-DR antigen alpha chain by using a synthetic oligonucleotide as a hybridization probe. [PDF]

, 1982
D Stetler, Hasi R. Das, Jack H. Nunberg, Randall K. Saiki, R Sheng-Dong, Kary B. Mullis, S M Weissman, M Kellis   +7 more
openalex   +1 more source

Constitutive Androstane Receptor in Macrophages Regulates Toll‐Like Receptor 4‐Mediated Innate Immune Responses Against Endotoxemic Liver Injury

Advanced Science, EarlyView.
The present study uncovers a novel role of constitutive androstane receptor (CAR) in inflammation‐mediated damage. CAR activation in macrophages inhibits proinflammatory macrophages by interacting with Tlr4, which protects against endotoxemic liver injury.
Renjie Cao, Tingting Zhao, Ying Wang, Shaofei Song, Yuan Li, Mengling Hou, Yanxin Zhang, Sengpeng Wong, Siqi Wang, Yuran Wang, Hong Peng, Min Huang, Yiming Jiang   +12 more
wiley   +1 more source

Editorial: Recent advancements in RNA-based and targeted therapeutics

Frontiers in Genetics
Yiming Meng, Viola Bianca Serio, Viola Bianca Serio, Yuquan Tong, Tao Huang, Elisa Frullanti, Elisa Frullanti, Maria Palmieri, Maria Palmieri   +8 more
doaj   +1 more source

Potentially prebiotic isocyanide activation chemistry drives RNA assembly.

Chem Commun (Camb)
Zhang SJ, Jia X, DasGupta S, Szostak JW.
europepmc   +1 more source

Towards improved anticancer properties of the G-quadruplex-forming T40231 aptamer through increased flexibility of nucleoside residues. [PDF]

Sci Rep
Kotkowiak W, Bartyś N, Pasternak A.
europepmc   +1 more source

Viral Systemic Movement Is Enhanced by Alteration of a Structural Phloem Protein by the Insect Vector

Advanced Science, EarlyView.
Aphids release salivary protein GLD into plants, which induces ROS in the phloem. This leads to the intermolecular disulfide bonds formation among SEO proteins, promoting their transition from the dispersed state to the aggregated state. SEO can interact with CMV CP.
Huijuan Guo, Qingyun Shi, Xiaoyu Ling, Yuting Wu, Lin He, Danyang Li, Keyan Zhu‐Salzman, Yucheng Sun   +7 more
wiley   +1 more source