Results 221 to 230 of about 449,240 (358)

SMC4 Promotes Prostate Cancer Cell Proliferation and Metastasis via the Rheb/mTOR Pathway

Advanced Science, EarlyView.
Structural maintenance of chromosome protein 4 (SMC4) has been implicated in prostate cancer metastasis. Knockdown of SMC4 in RM1‐LM cells significantly attenuates proliferation, migration, and lung metastasis in vivo. Furthermore, SMC4 interacts with GLUT1 (Slc2a1), thereby enhancing glycolysis, ATP production, and activation of the Rheb/mTOR pathway.
Wei Zhang, Siyuan Qin, Xiaokang Li, Ming Chang, Tianzi Wei, Xin Huang, Haibo Tong, Xia Guo, Yi Lu, Jian Zhang   +9 more
wiley   +1 more source

Widespread tissue delivery of antagomiRs via intramuscular administration. [PDF]

Mol Ther Methods Clin Dev
Messios C, Koutsoulidou A, Phylactou LA.
europepmc   +1 more source

Avian Tumor Virus RNA: A Comparison of Three Sarcoma Viruses and Their Transformation-Defective Derivatives by Oligonucleotide Fingerprinting and DNA-RNA Hybridization

, 1973
Michael M. C. Lai, Peter Duesberg, Jürgen Horst, Peter K. Vogt   +3 more
openalex   +1 more source

In Vivo Cytosolic Delivery of Biomolecules into Neurons for Super‐Resolution Imaging and Genome Modification

Advanced Science, EarlyView.
The N1 peptide specifically targets neurons, enabling cytosolic delivery of fluorescent dyes and proteins for super‐resolution imaging and functional genetic modification. Abstract Efficient delivery of biomolecules into neurons has significant impacts on therapeutic applications in the central nervous system (CNS) and fundamental neuroscience research.
Xiaoqian Ge, Joseph B. Wekselblatt, Scott Elmore, Bo Wang, Tongtong Wang, Renjinming Dai, Tingting Zhang, Harsh Dave, Mohammadaref Ghaderi, Athul Raj Anilkumar, Bill Wang, Shashank R. Sirsi, Jung‐Mo Ahn, Mikhail G. Shapiro, Yuki Oka, Carlos Lois, Zhenpeng Qin   +16 more
wiley   +1 more source

RETRACTED: Léon et al. 6-Pyrazolylpurine as an Artificial Nucleobase for Metal-Mediated Base Pairing in DNA Duplexes. <i>Int. J. Mol. Sci.</i> 2016, <i>17</i>, 554. [PDF]

Int J Mol Sci
Léon JC, Sinha I, Müller J.
europepmc   +1 more source

Evaluation of the governing parameters in oligonucleotides separation by hydrophilic interaction liquid chromatography using fractional factorial designs followed by surface response optimization [PDF]

, 2012
Alvarez Porebski, Piotr Wiktor, Lynen, Frederic, Sandra, Patrick   +2 more
core   +1 more source

Occurrence of Uridylate-Rich Oligonucleotide Regions in Heterogeneous Nuclear RNA of HeLa Cells

, 1972
George R. Molloy, William Thomas, James Darnell   +2 more
openalex   +1 more source

In Situ and Real‐Time Multi‐Modality Imaging Guided Orderly Triple‐Therapy of Tumors with a Multifunctional Nanodrug

Advanced Science, EarlyView.
A multifunctional AuNR@SiO2@MnO2@ DNA prodrugs (ASMD) nanodrug is designed to establish an in situ and real‐time photoacoustic (PA)/magnetic resonance (MR)/fluorescence (FL) multi‐modality imaging guided orderly photothermal therapy (PTT)/chemodynamic therapy (CDT)/gene therapy (GT) triple‐therapy of tumor.
Chaoyi Yang, Yuexuan Meng, Ying An, Jing Jia, Yuru Wang, Guangming Li, Yiran Li, Shan Wu, Chengyao Geng, Yunlong Chen, Huangxian Ju   +10 more
wiley   +1 more source

Selection and characterization of DNA aptamers targeting the surface Borrelia protein CspZ with high-throughput cross-over SELEX. [PDF]

Commun Biol
Guérin M, Vandevenne M, Matagne A, Aucher W, Verdon J, Paoli E, Ducrotoy J, Octave S, Avalle B, Maffucci I, Padiolleau-Lefèvre S.   +10 more
europepmc   +1 more source

Identification of promoter-proximal oligonucleotides and a unique dinucleotide, pppGpC, from in vitro transcription products of vesicular stomatitis virus [PDF]

, 1981
P K Chanda, A K Banerjee
openalex   +1 more source