Results 221 to 230 of about 584,539 (379)

An antibody uniquely binding short 2'-O-methyl RNA oligonucleotide duplexes: formation and recognition of target duplexes on cell surfaces. [PDF]

Front Immunol
Dunn IS, Lawler MM, Fagundes L, Simoes Junior M, Mangold A, Rinaldi D, Rose LB, Kurnick JT.   +7 more
europepmc   +1 more source

Antisense oligonucleotides as therapeutic agents [PDF]

, 1999
Umberto Galderisi, Antonino Cascino, Antonio Giordano   +2 more
openalex   +1 more source

CEt KRAS Antisense Oligonucleotide AZD4785 [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

Nap1L4a Cooperates with Scl/Klf1 to Recruit H2A.Z in Mediating Interactions Among Cis‐Regulatory Elements and Transcription Required for Primitive Erythropoiesis in Zebrafish

Advanced Science, EarlyView.
Nap1l4a is required in erythropoiesis and hypoxia responses via physical interaction with Klf1 and Scl to recruit the histone variant H2A.Z. This facilitates its associated cis‐regulatory element (CRE) remodeling and the consequent chromatin assembly, and activates the transcription of erythroid lineage‐specific genes.
JiaHao Shi, FuMing Lai, Zheng Shen, XiaoYan Zhang, HanFei Wang, WenYe Liu, YunLong Wang, KuanYu Li, GuoLiang Li, YaPing Fang, Jing‐Xia Liu   +10 more
wiley   +1 more source

Targeted Inhibition of Oncogenic microRNAs miR-21, miR-17, and miR-155 Suppresses Tumor Growth and Modulates Immune Response in Colorectal Cancer. [PDF]

Pharmaceutics
Patutina O, Sen'kova A, Miroshnichenko S, Awad M, Markov O, Gladkikh D, Savin I, Seroklinova E, Zhukov S, Kupryushkin M, Maslov M, Vlassov V, Zenkova M.   +12 more
europepmc   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

Sequence-specific fluorescence turn-on arises from base pairing-templated tautomerism in the tricyclic cytidine analogue ^DEAtC. [PDF]

RSC Chem Biol
Shalamberidze A, Pearce HR, Cooksy AL, Purse BW.   +3 more
europepmc   +1 more source

Antisense oligonucleotides targeted against protein kinase c α inhibit proliferation of cultured avian myoblasts [PDF]

, 2000
Daniela Andrea Capiati, Guillermo Vázquez, María T. Tellez de Iñon, R. Boland   +3 more
openalex   +1 more source

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

A cholesterol-responsive hepatic tRNA-derived small RNA regulates cholesterol homeostasis and atherosclerosis development. [PDF]

Nat Commun
Li X, Hernandez R, Zhang X, Tang S, Yuan X, Wu J, Pham K, Rawal HC, Heinrich EC, Zhang S, Chen Q, Zhou T, Zhou C.   +12 more
europepmc   +1 more source