Results 21 to 30 of about 37,441 (229)

Global Energy Matching Method for Atomistic-to-Continuum Modeling of Self-Assembling Biopolymer Aggregates [PDF]

open access: yes, 2010
This paper studies mathematical models of biopolymer supramolecular aggregates that are formed by the self-assembly of single monomers. We develop a new multiscale numerical approach to model the structural properties of such aggregates. This theoretical
E W.   +5 more
core   +1 more source

A Novel Gelatinase from Marine Flocculibacter collagenilyticus SM1988: Characterization and Potential Application in Collagen Oligopeptide-Rich Hydrolysate Preparation

open access: yesMarine Drugs, 2022
Although the S8 family in the MEROPS database contains many peptidases, only a few S8 peptidases have been applied in the preparation of bioactive oligopeptides.
Jian Li   +10 more
doaj   +1 more source

Identification of hepta-histidine as a candidate drug for Huntington's disease by in silico-in vitro- in vivo-integrated screens of chemical libraries. [PDF]

open access: yes, 2016
We identified drug seeds for treating Huntington's disease (HD) by combining in vitro single molecule fluorescence spectroscopy, in silico molecular docking simulations, and in vivo fly and mouse HD models to screen for inhibitors of abnormal ...
Chen, Xigui   +17 more
core   +2 more sources

Antioxidant and Immunomodulatory Properties of Chia Protein Hydrolysates in Primary Human Monocyte–Macrophage Plasticity

open access: yesFoods, 2022
Chia (Salvia hispanica L.) seed has high potential in the development of functional food due to its protein content with a special amino acid profile.
Alvaro Villanueva-Lazo   +6 more
doaj   +1 more source

Short peptide sequences: current knowledge and future prospects [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2021
According to modern knowledge, the biological effect of many peptides is mediated by their short-chain fragments – oligopeptides – ranging from 2 to 20 amino acids and the activity of short peptides often significantly exceeds the activity of the peptide
C. M. Nasadyuk
doaj   +1 more source

Crystallization of the oligopeptide-binding protein AppA from Bacillus subtilis [PDF]

open access: yes, 2004
AppA is the membrane-anchored extracellular receptor component of an ABC transporter responsible for the uptake of oligopeptides into Bacillus subtilis.
Blagova, E   +6 more
core   +1 more source

A genome-wide analysis of nonribosomal peptide synthetase gene clusters and their peptides in a Planktothrix rubescens strain

open access: yesBMC Genomics, 2009
Background Cyanobacteria often produce several different oligopeptides, with unknown biological functions, by nonribosomal peptide synthetases (NRPS).
Nederbragt Alexander J   +4 more
doaj   +1 more source

Oligopeptides as Biomarkers of Cyanobacterial Subpopulations. Toward an Understanding of Their Biological Role

open access: yesToxins, 2014
Cyanobacterial oligopeptides comprise a wide range of bioactive and/or toxic compounds. While current research is strongly focused on exploring new oligopeptide variants and their bioactive properties, the biological role of these compounds remains ...
Ramsy Agha, Antonio Quesada
doaj   +1 more source

De novo Design of G Protein-Coupled Receptor 40 Peptide Agonists for Type 2 Diabetes Mellitus Based on Artificial Intelligence and Site-Directed Mutagenesis

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
G protein-coupled receptor 40 (GPR40), one of the G protein-coupled receptors that are available to sense glucose metabolism, is an attractive target for the treatment of type 2 diabetes mellitus (T2DM).
Xu Chen   +9 more
doaj   +1 more source

Achiral dye/surfactant heteroaggregates for chiral sensing of phosphocholines [PDF]

open access: yes, 2015
An investigation, based on absorption and circular dichroism spectroscopy, was carried out on assemblies formed in water upon the interaction of heteroaggregates, composed of dyes (Congo Red or Evans Blue) and cetyltrimethylammonium bromide (CTAB), with ...
Altieri, Barbara   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy