Results 191 to 200 of about 188,140 (283)

Metagenomic mining reveals novel Cas12 subtypes and their evolutionary diversification

open access: yesiMetaOmics, EarlyView.
We identified 4112 Cas12 Proteins and 6 new Cas12 subtypes, revealed their significant diversity in N‐terminal regions, repeat sequences, and sequences motifs. We developed an AI‐driven algorithm, Cas12fam, which allows precise annotation of 18 distinct domains in Cas12 proteins.
Meixia Yu   +11 more
wiley   +1 more source

Synthesis, Conformal Analysis, and Antibody Binding of Staphylococcus aureus Capsular Polysaccharide Type 5 Oligosaccharides. [PDF]

open access: yesAngew Chem Int Ed Engl
Østerlid KE   +15 more
europepmc   +1 more source

Optimization of bioactive compounds extraction from Rosa canina L. pseudofruit through the action of two hydrolytic enzyme preparations

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni   +6 more
wiley   +1 more source

Dietary Mannan Oligosaccharides Enhance Lactational Performance, Nutrient Metabolism, Plasma Metabolomics, and Gut Microbiota in Dezhou Donkeys. [PDF]

open access: yesInt J Mol Sci
Wang T   +13 more
europepmc   +1 more source

Immunological effects of alpha‐lactalbumin‐enriched low‐protein infant formula: A randomized controlled trial

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Breast‐fed (BF) have lower risk of infections during infancy compared to those formula‐fed (FF). A higher content of alpha‐lactalbumin (α‐lac) in breast milk, which may promote a more favorable gut microbiota, could be one reason.
Ulrika T. Nilsson   +7 more
wiley   +1 more source

Stapling of β-Glucans Increases Antibody Binding. [PDF]

open access: yesJ Am Chem Soc
Ledvinka J   +5 more
europepmc   +1 more source

Human Breast Milk‐Derived Exosomal FP671120.4 Inhibits Macrophage M1 Polarization via Modulating the ELAVL1/Nrf2 Axis in Sepsis‐Associated Liver Injury

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sepsis‐associated liver injury (SALI) plays a major role in aggravating disease progression and worsening prognosis in patients with sepsis. Macrophage polarization is a key factor in the modulation of SALI progression. Recent studies have shown that human breast milk‐derived exosomes (HBM‐Exos) regulate processes involved in macrophage ...
Zhao‐Bin Yang   +3 more
wiley   +1 more source

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