Results 61 to 70 of about 92,911 (310)

Activation of Thioglycosides with Copper(II) Bromide

Molecules, 2022
Reported herein is a new protocol for glycosidation of alkyl and aryl thioglycosides in the presence of copper(II) bromide. While the activation with CuBr2 alone was proven suitable for reactive glycosyl donors, the activation of less reactive donors was
Faranak Pooladian, Samira Escopy, Alexei V. Demchenko   +2 more
doaj   +1 more source

Potent Cross‐neutralizing Antibodies Reveal Vulnerabilities of Henipavirus Fusion Glycoprotein

Advanced Science, EarlyView.
Hendra and Nipah viruses (HNVs) pose significant threats to global health. This work reports potent cross‐neutralizing antibodies targeting the fusion glycoprotein (F) and reveals shared features of these antibodies and vulnerabilities of F, thereby guiding the rational design of countermeasures against HNVs and similar pathogens.
Yi Ren, Pengfei Fan, Xinghai Zhang, Ting Fang, Zhengshan Chen, Yanfeng Yao, Xiangyang Chi, Guanying Zhang, Xiaofan Zhao, Bingjie Sun, Fangxu Li, Zixuan Liu, Zhenwei Song, Baoyue Zhang, Cheng Peng, Entao Li, Yilong Yang, Jianmin Li, Sandra Chiu, Changming Yu   +19 more
wiley   +1 more source

Crystallization of L‐Cysteine in Heavy Water Induces Intrinsic Fluorescence

Angewandte Chemie, EarlyView.
Crystallization of L‐Cysteine in D2O${\rm D}_2{\rm O}$ generates a remarkably different structure compared to H2O${\rm H}_2{\rm O}$. The crystals formed in D2O${\rm D}_2{\rm O}$ display enhanced intrinsic fluorescence, and using state‐of‐the‐art excited state simulations, we determine the molecular origins of this luminescence and propose design ...
Debarshi Banerjee, Sonika Chibh, Om Shanker Tiwari, Gonzalo Díaz Mirón, Marta Monti, Hadar R. Yakir, Shweta Pawar, Dror Fixler, Linda J. W. Shimon, Ehud Gazit, Ali Hassanali   +10 more
wiley   +2 more sources

Targeted Intervention Strategies for Maternal–Offspring Transmission of Christensenellaceae in Pigs via a Deep Learning Model

Advanced Science, EarlyView.
This study deciphers maternal‐driven microbial transmission in pigs using a deep learning model (maternal–offspring microbial transmission model), identifying Christensenellaceae R‐7 group as a key transmitted taxon. Filtered galacto‐oligosaccharides‐targeted Christensenellaceae R‐7 group alters offspring microbial functions via maternal ...
Haibo Shen, Xiaokang Ma, Longlin Zhang, Hao Li, Jichang Zheng, Shengru Wu, Ke Zuo, Yulong Yin, Jing Wang, Bie Tan   +9 more
wiley   +1 more source

Fresh and Stored Sugar Beet Roots as a Source of Various Types of Mono- and Oligosaccharides

Molecules, 2022
Although sugar beets are primarily treated as a source of sucrose, due to their rich chemical composition, they can also be a source of other carbohydrates, e.g., mono- and oligosaccharides.
Radosław Michał Gruska, Andrzej Baryga, Alina Kunicka-Styczyńska, Stanisław Brzeziński, Justyna Rosicka-Kaczmarek, Karolina Miśkiewicz, Teresa Sumińska   +6 more
doaj   +1 more source

Enhancing Cold Adaptation of Bidomain Amylases by High‐Throughput Computational Engineering

Angewandte Chemie, EarlyView.
This work uncovers molecular determinants of cold adaptation in bidomain amylases by combining MD simulations and biochemical assays, revealing that increased domain separation drives enhanced activity at low temperatures. Guided by this principle, high‐throughput in silico linker screening of mesophilic psA was performed, yielding variant psA121 with ...
Ning Ding, Yaoyukun Jiang, Robbie Ge, Qianzhen Shao, Wook Shin, Xinchun Ran, Zhongyue J. Yang   +6 more
wiley   +2 more sources

Assembling Hexahedral Supramolecular Nano‐Aggregates on Rice Wax Layer Matrices to Promote the Leaf Deposition and Bioavailability of Bactericides for Plant Protections

Advanced Science, EarlyView.
To address the problem of off‐target movement and low bioavailability of pesticides, two anisotropic supramolecular building units (BiTA18@β‐CD and BiTA18@γ‐CD) have been invented that can self‐assemble into nano‐sized hexagonal cuboids on the rice microcrystalline matrix. This manipulation realizes the enhanced utilization of bactericides for rice and
Run Yang, Jinghan Yang, Min Liu, Juan Liu, Peiyi Wang   +4 more
wiley   +1 more source

MdDSK2a‐Like‐MdMTA Module Functions in Apple Cold Response via Regulating ROS Detoxification and Cell Wall Deposition

Advanced Science, EarlyView.
Under cold stress, MdDSK2a‐like is degraded via the 26S proteasome pathway, thereby alleviating the degradation of MdMTA induced by the 26S proteasome and autophagy pathways mediated by MdDSK2a‐like. The accumulated MdMTA increases the m6A levels of cold‐responsive genes, thereby contributing to increased ROS detoxification, deposition of cell wall, as
Nan Hou, Jieqiang He, Chana Bao, Fang Zhi, Xiaoxia Shen, Yu Liu, Chaoshuo Li, Tianle Fan, Xinyue Yang, Baohua Chu, Gege Qin, Zeyuan Liu, Chuang Mei, Bin Tan, Jiancan Feng, Fengwang Ma, Mickael Malnoy, Xuewei Li, Qingmei Guan   +18 more
wiley   +1 more source

Integrated Green Biorefinery for the Production of Anthocyanins, Fermentable Sugars, and High Pure Lignin from Miscanthus × giganteus

Advanced Energy and Sustainability Research, EarlyView.
Integrated production of pigments, fermentation sugars, and pure lignin has been investigated for the creation of profitable biorefinery developments. Choline chloride‐based natural deep eutectic solvents possess unique solvent capabilities to interact with plant cell wall components to disintegrate lignin‐carbohydrate complex.
Tirath Raj, Vijay Singh
wiley   +1 more source

Cell Membrane‐Coated Lipid Nanoparticles for Drug Delivery

Aggregate, EarlyView.
This review highlights recent progress in cell membrane‐coated lipid nanoparticles (CMC‐LNPs), focusing on their design, preparation methods, functional integration, and biomedical applications. It discusses various types of LNPs and coating strategies, characterization techniques, therapeutic functions, and applications.
Moataz B. Zewail, Guangze Yang, Yilong Fan, Yue Hui, Chun‐Xia Zhao, Yun Liu   +5 more
wiley   +1 more source