Results 71 to 80 of about 188,140 (283)

Metronidazole‐Loaded Cyclodextrin Nanogels for Antibacterial Therapy and Microbiota Regulation in Periodontitis

open access: yesAdvanced Healthcare Materials, EarlyView.
A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji   +8 more
wiley   +1 more source

Effect of Soaking and Boiling on Anti-nutritional Factors, Oligosaccharide Contents and Protein Digestibility of Newly Developed Bambara Groundnut Cultivars

open access: yesTurkish Journal of Agriculture: Food Science and Technology, 2017
Newly developed Bambara groundnut (Vigna subterranea L.) seeds (Accessions No: TVSU 5 – Bambara Groundnut White (BGW) and TVSU 146 – Bambara Groundnut Brown (BGB)) were collected from International Institute of Tropical Agriculture (IITA), Nigeria ...
Olaposi Adeleke   +3 more
doaj   +1 more source

Differential Dynamics at Glycosidic Linkages of an Oligosaccharide as Revealed by 13C NMR Spin Relaxation and Stochastic Modeling [PDF]

open access: yes, 2018
Among biomolecules, carbohydrates are unique in that not only can linkages be formed through different positions but the structures may also be branched.
Abragam A.   +6 more
core   +1 more source

Formulating Smart All‐in‐One Chitosan Hydrogel for High Performance Wound Dressing

open access: yesAdvanced Healthcare Materials, EarlyView.
An innovative approach to fabricating a thermosensitive, highly swelling, degradable, and antibacterial hydrogel composed of a chitosan‐g‐NIPAAm/PVA/PVP copolymer, integrated with AgNPs, for use in wound dressing applications. The hydrogel demonstrates enhanced performance, accelerating the wound healing process.
Chia‐Chi Lin   +8 more
wiley   +1 more source

Molecular Simulations of Polymer‐based Drug Nanocarriers: From Physical and Structural Properties to Controlled Release

open access: yesAdvanced Healthcare Materials, EarlyView.
Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao   +4 more
wiley   +1 more source

Decoding a Gut Commensal Signal: Structural and Immunological Profiling of Segatella Copri Lipopolysaccharide

open access: yesAngewandte Chemie, EarlyView.
The lipopolysaccharide (LPS) of Segatella copri is a structurally unique, immunomodulatory glycoconjugate. Combining mass spectrometry (MS), nuclear magnetic resonance (NMR), and cytometry by time‐of‐flight (CyTOF), we uncover a rough‐type LPS with reduced TLR4 agonism and selective monocyte effects, further highlighting the key role of LPS chemistry ...
Luca De Simone Carone   +17 more
wiley   +2 more sources

Synthesis of the Oligosaccharides Related to Branching Sites of Fucosylated Chondroitin Sulfates from Sea Cucumbers

open access: yesMarine Drugs, 2015
Natural anionic polysaccharides fucosylated chondroitin sulfates (FCS) from sea cucumbers attract great attention nowadays due to their ability to influence various biological processes, such as blood coagulation, thrombosis, angiogenesis, inflammation ...
Nadezhda E. Ustyuzhanina   +4 more
doaj   +1 more source

Reclamation of Marine Chitinous Materials for Chitosanase Production via Microbial Conversion by Paenibacillus macerans [PDF]

open access: yes, 2018
[[abstract]]: Chitinous materials from marine byproducts elicit great interest among biotechnologists for their potential biomedical or agricultural applications.
Anh Dzung Nguyen   +4 more
core   +1 more source

Honeysuckle‐Derived Nanovesicles Regulate Gut Microbiota for the Treatment of Inflammatory Bowel Disease

open access: yesAdvanced Science, EarlyView.
This study explores honeysuckle‐derived nanovesicles (HNVs) for treating inflammatory bowel disease. Orally administered HNVs alleviates colitis in mice by repairing the gut barrier, reducing inflammation, and restoring a healthy gut microbiota.
Yuanyuan Wang   +11 more
wiley   +1 more source

Iron‐Catalyzed Highly Stereospecific Glycosylation with Glycal Epoxides

open access: yesAngewandte Chemie, EarlyView.
We report an iron‐catalyzed, highly stereospecific glycosylation method with glycal epoxides, which is effective for a broad range of substrates, including previously challenging, sterically hindered secondary acceptors and glucuronic ester epoxide donors.
Xiao‐Wen Zhang   +5 more
wiley   +2 more sources

Home - About - Disclaimer - Privacy