Results 11 to 20 of about 1,725 (146)

Omadacycline for the treatment of acute bacterial skin and skin structure infections: a systematic review and network meta-analysis [PDF]

BMC Infectious Diseases
Background Few studies have compared the efficacy and safety of omadacycline with other treatments for acute bacterial skin and skin structure infections (ABSSSI). Therefore, updated meta-analyses on this topic is necessary.
Wen-qiang Kong, Yun-feng Shu , Juan Tang, Shi-qin Li, Hong Zhong, Xuan-yi Zhang   +5 more
doaj   +2 more sources

Omadacycline for the treatment of patients with Legionella pneumophila pneumonia after experiencing liver dysfunction: case series [PDF]

Frontiers in Microbiology
IntroductionAntibiotics frequently induce abnormal liver function. Omadacycline is a novel aminomethylcycline antibiotic, which shows potent activity against Gram-positive and Gram-negative aerobic, anaerobic, and atypical (including Legionella ...
Ani Zhu, Qian Ma, Zhiyan Liu
doaj   +2 more sources

Efficacy of omadacycline in the treatment of Legionella pneumonia: a case report [PDF]

Frontiers in Cellular and Infection Microbiology
Legionella, one of the main pathogens that causes community-acquired pneumonia, can lead to Legionella pneumonia, a condition characterized predominantly by severe pneumonia.
Yao Wang, Yao Wang, Shui-Min Yi, Shui-Min Yi, Si-Min Huang, Si-Min Huang, Wei-Xin Xu, Yi-Wen Wei, Qiang Qu, Jian Qu, Jian Qu   +10 more
doaj   +2 more sources

Clinical Efficacy and Safety of Omadacycline Versus Tigecycline in Treating Severe Pneumonia Caused by Carbapenem-Resistant Gram-Negative Bacilli: A Retrospective Cohort Study [PDF]

Infection and Drug Resistance
Ye Zhang,1 Fei Wang,2 Min Wang,1 Wenhui Xu,3 Aiping Wang,3 Yueping Ding2 1Department of Pharmacy, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People’s Republic of China; 2Department of Intensive Care Unit ...
Zhang Y, Wang F, Wang M, Xu W, Wang A, Ding Y   +5 more
doaj   +2 more sources

Intravenous Versus Oral Omadacycline or Linezolid for Acute Bacterial Skin and Skin Infections: A post hoc Analysis of the OASIS Trials [PDF]

Infectious Diseases and Therapy
Introduction Appropriate oral antibiotic therapy for the treatment of acute bacterial skin and skin structure infections (ABSSSI) is a challenge, as current oral treatment guidelines do not fully cover the most common skin pathogens.
George D. Rodriguez, Nathan Warren, Roman Yashayev, Surya Chitra, Maria Amodio-Groton, Kelly Wright   +5 more
doaj   +2 more sources

Omadacycline for the treatment of severe pneumonia caused by Chlamydia psittaci complicated with acute respiratory distress syndrome during the COVID-19 pandemic [PDF]

Frontiers in Medicine
IntroductionChlamydia psittaci infection in humans is a rare cause that mainly present as community-acquired pneumonia. Severe Chlamydia psittaci pneumonia can lead to acute respiratory distress syndrome (ARDS), septic shock, or multiple organ ...
Dao-Xin Wang, Dao-Xin Wang, Ling-Xi Xiao, Ling-Xi Xiao, Xin-Yu Deng, Xin-Yu Deng, Wang Deng, Wang Deng   +7 more
doaj   +2 more sources

Activity of omadacycline in vitro against Clostridioides difficile and preliminary efficacy assessment in a hamster model of C. difficile-associated diarrhoea

Journal of Global Antimicrobial Resistance, 2022
: Objectives: Antibiotics are associated with increased risk of Clostridioides difficile infection, which has limited treatment options. We assessed in vitro activity of omadacycline (an aminomethylcycline antibiotic) against the C.
Raina Gay Leahy, Alisa W. Serio, Kelly Wright, Maria M. Traczewski, S. Ken Tanaka   +4 more
doaj   +1 more source

Preclinical <i>in vitro</i> and <i>in vivo</i> evaluation of omadacycline against multidrug-resistant <i>Acinetobacter baumannii</i>. [PDF]

Antimicrob Agents Chemother
Vanachayangkul P, Ruamsap N, Caridha D, Imerbsin R, Ball E, Chattagul S, Tungtang A, Gonwong S, Kodchakorn C, Lertsethtakarn P, Silapong S, Chaisatit C, Khemnu N, Boudreaux D, Boonyalai N, Demons S, Pierce JV, Martin M, Anastasiou D, Serio AW, Vesely B, Lanteri CA.   +21 more
europepmc   +2 more sources

Omadacycline exhibits anti-inflammatory properties and improves survival in a murine model of post-influenza MRSA pneumonia. [PDF]

Antimicrob Agents Chemother
Gomi S, Price E, Burgoyne H, Faozia S, Katahira E, McIndoo E, Nmaju AA, Sharma K, Aghazadeh-Habashi A, Bryant AE, Stevens DL, Pierce JV, Serio AW, Hobdey SE.   +13 more
europepmc   +2 more sources

Omadacycline for treatment of acute bacterial infections: a meta-analysis of phase II/III trials

BMC Infectious Diseases, 2023
Objective This study aims to assess the clinical efficacy and safety of omadacycline for the treatment of acute bacterial infections. Methods A search of PubMed, Embase, Cochrane Library, and Clinical Trials was conducted up to July 1, 2022.
Fei Lin, Rong He, Bin Yu, Bowen Deng, Baodong Ling, Mingyong Yuan   +5 more
doaj   +1 more source