Results 21 to 30 of about 1,785 (194)

Case Report: Effective use of omadacycline in Japanese spotted fever [PDF]

open access: yesFrontiers in Medicine
This case report describes the efficacy of omadacycline for the treatment of Japanese spotted fever. A 57-years-old woman presented with fever and maculopapular rash, followed by dyspnea.
Xue Dai   +5 more
doaj   +2 more sources

Treatment of chronic rhinosinusitis and acute recurring rhinosinusitis with omadacycline: A case series [PDF]

open access: yesIDCases
Chronic rhinosinusitis (CRS), defined as persistent inflammation of the sinuses lasting longer than 12 weeks, and recurrent acute rhinosinusitis (RARS), characterized by multiple distinct episodes of acute bacterial sinusitis within a year, are among the
Andrew Pugliese
doaj   +2 more sources

Omadacycline Pharmacokinetics: Characteristics, Contributing Factors, and Clinical Significance [PDF]

open access: yesDrugs in R&D
Omadacycline is a novel tetracycline with a wide range of antibacterial activity. A comprehensive understanding of the factors influencing its metabolic processes is essential to optimize its therapeutic benefits and minimize any potential negative ...
Huan Sun   +5 more
doaj   +2 more sources

A case of severe Legionella pneumonia treated with omadacycline and nemonoxacin [PDF]

open access: yesRespiratory Medicine Case Reports
Severe Legionella pneumophila pneumonia carries high mortality, and treatment is challenged by emerging resistance to conventional fluoroquinolones/macrolides and diagnostic delays.
Tingrui Zhao, Yukai Chen, He Sun
doaj   +2 more sources

Efficacy and safety of omadacycline for the treatment of infectious diseases: a real-world, retrospective study of 2587 patients [PDF]

open access: yesFrontiers in Pharmacology
ObjectivePrevious randomized controlled trials have shown good efficacy and safety of omadacycline in patients with infectious diseases, but relevant real-world evidence is still insufficient.
Jian Liu   +7 more
doaj   +2 more sources

A real-world pharmacovigilance analysis of omadacycline in FDA adverse event reporting system (FAERS) database [PDF]

open access: yesFrontiers in Pharmacology
ObjectiveOmadacycline is a newly launched drug of tetracycline. Therefore, it is necessary to comprehensive evaluate reports on the safety of omadacycline in large, real-world populations.
Xueping Shi   +4 more
doaj   +2 more sources

Multicenter Real-World Outpatient Use of Intravenous Omadacycline [PDF]

open access: yesInfectious Diseases and Therapy
Introduction Omadacycline is indicated for the treatment of acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia.
Lucinda J. Van Anglen   +2 more
doaj   +2 more sources

Omadacycline for the treatment of skin and soft tissue infections

open access: yesCurrent Opinion in Infectious Diseases
Purpose of review To evaluate the current evidence on the use of omadacycline for the treatment of skin and soft tissue infections (SSTIs). Recent findings This narrative review examines the available data on the pharmacology, clinical efficacy, safety profile, and comparative ...
Vena, Antonio   +4 more
core   +4 more sources

Preclinical in vitro and in vivo evaluation of omadacycline against multidrug-resistant Acinetobacter baumannii [PDF]

open access: yesAntimicrobial Agents and Chemotherapy
Acinetobacter baumannii is an increasing cause of chronic wound infections, especially in military operational settings, and is resistant to many currently available antimicrobial therapies, making treatment options limited.
Pattaraporn Vanachayangkul   +21 more
doaj   +2 more sources

Omadacycline for Diverse Infections in China: A Real-World Analysis of Efficacy and Safety

open access: yesInfectious Diseases and Therapy
Introduction The efficacy and safety of omadacycline have been primarily documented through Phase III clinical trials; however, there are limited data from real-world clinical settings.
Weiwen Gao   +7 more
doaj   +2 more sources

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