Omadacycline Is Highly Active In Vitro against Mycoplasma genitalium
Microbiology Spectrum, 2022 Here, we performed in vitro susceptibility testing on 10 Mycoplasma genitalium isolates against omadacycline, minocycline, tetracycline, doxycycline, moxifloxacin, levofloxacin, and azithromycin.
Ken B. Waites +4 more
doaj +3 more sources
Omadacycline therapy for Mycobacterium abscessus species infections
Internal Medicine Journal, Volume 53, Issue 12, Page 2257-2263, December 2023., 2023 Abstract Background Antimicrobial resistance and therapy‐related adverse effects make Mycobacterium abscessus treatment challenging. Omadacycline is a novel, bioavailable aminomethylcycline with favourable in vitro activity against M. abscessus. Aims To describe a case report and review the published literature describing outcomes for M.
Paul R. Ingram +5 more
wiley +3 more sources
Case Report: Omadacycline in the treatment of macrolide-unresponsive Mycoplasma pneumoniae pneumonia in an adolescent patient [PDF]
Frontiers in Cellular and Infection Microbiology, 2023 Omadacycline is a novel tetracycline antibiotic that exhibits good in vitro antibacterial activity against atypical pathogens such as Mycoplasma pneumoniae. It is approved for the treatment of adults with community-acquired bacterial pneumonia.
Limin Xu, Changquan Fang
doaj +3 more sources
Omadacycline Potentiates Clarithromycin Activity Against Mycobacterium abscessus [PDF]
Frontiers in Pharmacology, 2021 Mycobacterium abscessus is a difficult respiratory pathogen to treat, when compared to other nontuberculus mycobacteria (NTM), due to its drug resistance.
Bui Thi Bich Hanh +7 more
doaj +3 more sources
Clinical Efficacy and Safety of Omadacycline Versus Tigecycline in Treating Severe Pneumonia Caused by Carbapenem-Resistant Gram-Negative Bacilli: A Retrospective Cohort Study. [PDF]
Infect Drug ResistYe Zhang,1 Fei Wang,2 Min Wang,1 Wenhui Xu,3 Aiping Wang,3 Yueping Ding2 1Department of Pharmacy, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People’s Republic of China; 2Department of Intensive Care Unit ...
Zhang Y +5 more
europepmc +2 more sources
Omadacycline treatment of severe Chlamydia psittaci pneumonia with septic shock diagnosed via metagenomic next-generation sequencing [PDF]
Journal of Infection in Developing CountriesIntroduction: Parrot fever, caused by Chlamydia psittaci, is a zoonotic disease typically treated with tetracyclines. Omadacycline, a novel aminomethyl tetracycline, has limited reports on its efficacy in severe Chlamydia psittaci pneumonia in the ...
Ping Xu, Zhitong Huang
doaj +3 more sources
Intravenous Versus Oral Omadacycline or Linezolid for Acute Bacterial Skin and Skin Infections: A post hoc Analysis of the OASIS Trials [PDF]
Infectious Diseases and TherapyIntroduction Appropriate oral antibiotic therapy for the treatment of acute bacterial skin and skin structure infections (ABSSSI) is a challenge, as current oral treatment guidelines do not fully cover the most common skin pathogens.
George D. Rodriguez +5 more
doaj +3 more sources
Efficacy of omadacycline in the treatment of Legionella pneumonia: a case report [PDF]
Frontiers in Cellular and Infection MicrobiologyLegionella, one of the main pathogens that causes community-acquired pneumonia, can lead to Legionella pneumonia, a condition characterized predominantly by severe pneumonia.
Yao Wang +10 more
doaj +3 more sources
Journal of Global Antimicrobial Resistance, 2022 : Objectives: Antibiotics are associated with increased risk of Clostridioides difficile infection, which has limited treatment options. We assessed in vitro activity of omadacycline (an aminomethylcycline antibiotic) against the C.
Raina Gay Leahy +4 more
doaj +1 more source
Omadacycline for treatment of acute bacterial infections: a meta-analysis of phase II/III trials
BMC Infectious Diseases, 2023 Objective This study aims to assess the clinical efficacy and safety of omadacycline for the treatment of acute bacterial infections. Methods A search of PubMed, Embase, Cochrane Library, and Clinical Trials was conducted up to July 1, 2022.
Fei Lin +5 more
doaj +1 more source