Results 61 to 70 of about 1,725 (146)

Immunomodulatory activity of omadacycline in vitro and in a murine model of acute lung injury

mSphere
Cystic fibrosis (CF) is characterized by chronic airway obstruction, infection, and inflammation leading to progressive loss of lung function and eventual respiratory failure.
Madeline Sanders, Paul Beringer
doaj   +1 more source

In vitro activity of omadacycline against bacterial isolates from bone/joint infections and rare pathogens in the SENTRY antimicrobial surveillance program (2015–2023)

Journal of Global Antimicrobial Resistance
Objectives: Omadacycline is an aminomethylcycline (tetracycline class) antibacterial approved by the United States Food and Drug Administration (2018) for treatment of adults with acute bacterial skin and skin structure infection (ABSSSI) and community ...
Michael D. Huband, Paul R. Rhomberg, Kelley A. Fedler, Christopher Blankers, Diane Anastasiou, Alisa W. Serio, Mariana Castanheira   +6 more
doaj   +1 more source

Efficacy and Safety of Omadacycline Versus Linezolid in Acute Bacterial Skin and Skin Structure Infections in Persons Who Inject Drugs [PDF]

, 2022
Gregory J. Moran, Surya Chitra, Paul C. McGovern   +2 more
openalex   +1 more source

In vitro activity of cefiderocol, cefepime/enmetazobactam, cefepime/zidebactam, eravacycline, omadacycline, and other comparative agents against carbapenem-non-susceptible Pseudomonas aeruginosa and Acinetobacter baumannii isolates associated from bloodstream infection in Taiwan between 2018–2020

, 2021
Po‐Yu Liu, Wen‐Chien Ko, Wen‐Sen Lee, Po‐Liang Lu, Yen‐Hsu Chen, Shu‐Hsing Cheng, Min‐Chi Lu, Chi‐Ying Lin, Ting‐Shu Wu, Muh‐Yong Yen, Lih-Shinn Wang, Chang-Pan Liu, Pei‐Lan Shao, Yu-Lin Lee, Zhi‐Yuan Shi, Yao-Shen Chen, Fu‐Der Wang, Shu‐Hui Tseng, Chao‐Nan Lin, Yu‐Hui Chen, Wang‐Huei Sheng, Chun-Ming Lee, Hung-Jen Tang, Po‐Ren Hsueh   +23 more
openalex   +1 more source

Safety and Pharmacokinetics of the Aminomethylcycline Antibiotic Omadacycline Administered to Healthy Subjects in Oral Multiple-Dose Regimens [PDF]

, 2017
Lu Ann Bundrant, Evan Tzanis, Lynne Garrity-Ryan, Stephen A. Bai, Surya Chitra, Amy Manley, Stephen Villano   +6 more
openalex   +1 more source

In vitro Activity and Heteroresistance of Omadacycline Against Clinical Staphylococcus aureus Isolates From China Reveal the Impact of Omadacycline Susceptibility by Branched-Chain Amino Acid Transport System II Carrier Protein, Na/Pi Cotransporter Family Protein, and Fibronectin-Binding Protein

Frontiers in Microbiology, 2019
Omadacycline (Omad), a new tetracycline (Tet)-class broad-spectrum aminomethylcycline, has been reported to exhibit excellent potency against Gram-positive bacteria, including Staphylococcus aureus and Enterococci.
Bing Bai, Bing Bai, Zhiwei Lin, Zhiwei Lin, Zhangya Pu, Guangjian Xu, Guangjian Xu, Fan Zhang, Fan Zhang, Zhong Chen, Zhong Chen, Xiang Sun, Jinxin Zheng, Peiyu Li, Peiyu Li, Qiwen Deng, Qiwen Deng, Zhijian Yu, Zhijian Yu   +18 more
doaj   +1 more source

Omadacycline successfully treated severe Legionella pneumonia after moxifloxacin treatment failure: Case series

Frontiers in Pharmacology
Legionella is a significant pathogen responsible for community-acquired pneumonia and, less commonly, for hospital-acquired pneumonia. Legionella pneumophila, the most prevalent species within the Legionella genus, accounts for 80%–90% of human ...
Biyun Li, Laiyu Liu, Fei Li, Chunmei He, Yuan Chen, Xiaodong Tian, Zhenyu Liu, Weizhen Zhang   +7 more
doaj   +1 more source

Omadacycline treatment of severe Chlamydia psittaci pneumonia with septic shock diagnosed via metagenomic next-generation sequencing

Journal of Infection in Developing Countries
Introduction: Parrot fever, caused by Chlamydia psittaci, is a zoonotic disease typically treated with tetracyclines. Omadacycline, a novel aminomethyl tetracycline, has limited reports on its efficacy in severe Chlamydia psittaci pneumonia in the ...
Ping Xu, Zhitong Huang
doaj   +1 more source

In Vitro Activity of New Tetracycline Analogs Omadacycline and Eravacycline against Drug-Resistant Clinical Isolates of Mycobacterium abscessus [PDF]

, 2019
Amit Kaushik, Nicole C. Ammerman, Olumide Martins, Nicole Parrish, Eric L. Nuermberger   +4 more
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In Vitro Synergistic Effects of Omadacycline with Other Antimicrobial Agents against Mycobacterium abscessus [PDF]

, 2023
Keiji Fujiwara, Akio Aono, Takahiro Asami, Kozo Morimoto, Keisuke Kamada, Yuta Morishige, Yuriko Igarashi, Kinuyo Chikamatsu, Yoshiro Murase, Hiroyuki Yamada, Akiko Takaki, Satoshi Mitarai   +11 more
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