Results 51 to 60 of about 2,144 (203)

Whole genome sequencing and prediction of antimicrobial susceptibilities in non-tuberculous mycobacteria [PDF]

open access: yes, 2022
Non-tuberculous mycobacteria (NTM) are opportunistic pathogens commonly causing chronic, pulmonary disease which is notoriously hard to treat.
Lipman, M   +3 more
core   +1 more source

AdeABC Efflux Pump Controlled by AdeRS Two Component System Conferring Resistance to Tigecycline, Omadacycline and Eravacycline in Clinical Carbapenem Resistant Acinetobacter nosocomialis

open access: yesFrontiers in Microbiology, 2020
Carbapenem-resistant Acinetobacter nosocomialis (CRAn) is a significant public health concern. Tigecycline non-susceptible CRAn (Tn-CRAn) isolates have emerged worldwide.
Yi-Tzu Lee   +9 more
doaj   +1 more source

Omadacycline Enters the Ring: A New Antimicrobial Contender [PDF]

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2018
Omadacycline is a novel aminomethylcycline approved for the treatment of community‐acquired bacterial pneumonia and acute bacterial skin and skin structure infections. This article reviews existing data pertaining to the biochemistry, mechanism of action, pharmacokinetics/pharmacodynamics, in vitro activity, and current progress with omadacycline in ...
Katie E. Barber   +4 more
openaire   +2 more sources

Empiric treatment approach for the management of post-operative incisional infections with omadacycline

open access: yesFoot & Ankle Surgery: Techniques, Reports & Cases, 2023
: Background: Surgical wound dehiscence (SWD) is one of the most common complications of surgical incision sites after foot surgeries because of blood flow and circulation issues that may occur in the foot. Such SWD complications can potentially lead to
Philip Wrotslavsky
doaj   +1 more source

Emerging antibiotics for community-acquired pneumonia [PDF]

open access: yes, 2019
Introduction: Community-acquired pneumonia is the most common infection leading to hospitalization and death in all age groups, especially in elderly populations.
Cillóniz, Catia   +3 more
core   +1 more source

Pharmacokinetics and Pharmacodynamics of Oral and Intravenous Omadacycline [PDF]

open access: yesClinical Infectious Diseases, 2019
AbstractOral and intravenous (IV) omadacycline formulations are approved in the United States for treating acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia in adults. Oral omadacycline bioavailability is 34.5%; similar exposures are obtained following 300 mg oral and 100 mg IV doses.
Rodvold, Keith A, Pai, Manjunath P
openaire   +2 more sources

Preliminary, real-world, multicenter experience with omadacycline for Mycobacterium abscessus infections [PDF]

open access: yes, 2021
Twelve patients were treated with omadacycline (OMC) as part of a multidrug regimen ...
Alosaimy, Sara   +14 more
core   +2 more sources

New antibiotics for the treatment of acute bacterial skin and soft tissue infections in pediatrics [PDF]

open access: yes, 2020
Acute bacterial skin and soft tissue infections (aSSTIs) are a large group of diseases that can involve exclusively the skin or also the underlying subcutaneous tissues, fascia, or muscles.
Argentiero A.   +4 more
core   +2 more sources

Efficacies of omadacycline + amikacin + imipenem and an all-oral regimen omadacycline + clofazimine + linezolid in a mouse model of M. abscessus lung disease

open access: yesmSphere
Treatment outcomes for Mycobacteroides abscessus (Mab, also known as Mycobacterium abscessus) disease are still unsatisfactory, mainly due to issues with drug toxicity, tolerability, and efficacy.
Elisa H. Ignatius   +7 more
doaj   +1 more source

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