Results 71 to 80 of about 2,144 (203)

Activity and resistance mechanisms of the third generation tetracyclines tigecycline, eravacycline and omadacycline against nationwide Spanish collections of carbapenemase-producing Enterobacterales and Acinetobacter baumannii [PDF]

Multicenter study[Abstract] Introduction: The rise in multidrug-resistant bacteria challenges clinical microbiology. Tigecycline, eravacycline, and omadacycline show promise against carbapenem-resistant Enterobacterales and Acinetobacter baumannii ...
Alonso-García, Isaac, Arca-Suárez, Jorge, Beceiro, Alejandro, Blanco-Martín, Tania, Bou, Germán, Fernández-López, María del Carmen, García, Patricia, García-Pose, Andrea, González-Pinto, Lucía, Guijarro-Sánchez, Paula, Lasarte-Monterrubio, Cristina, Maceiras, Romina, Muras, Andrea, Outeda-García, Michelle, Rodríguez-Coello, Arianna, Vázquez-Ucha, Juan Carlos   +15 more
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A case study on Staphylococcus aureus bacteraemia: available treatment options, antibiotic R&D and responsible antibiotic-use strategies [PDF]

, 2020
Objectives This case study addresses: (i) antibiotic treatment options for Staphylococcus aureus bacteraemia (SAB), for both empirical and targeted therapy; (ii) the current status of and priorities for the antibiotic pipeline to ensure
Cavaleri, Marco, Gyssens, Inge C, Monnier, Annelie A, Tacconelli, Evelina, Årdal, Christine   +4 more
core   +1 more source

Omadacycline for the treatment of patients with Legionella pneumophila pneumonia after experiencing liver dysfunction: case series

Frontiers in Microbiology
IntroductionAntibiotics frequently induce abnormal liver function. Omadacycline is a novel aminomethylcycline antibiotic, which shows potent activity against Gram-positive and Gram-negative aerobic, anaerobic, and atypical (including Legionella ...
Ani Zhu, Qian Ma, Zhiyan Liu
doaj   +1 more source

Successful Treatment of Critically Severe Empyema With Bronchopleural Fistula via ECMO: A Case Report

Respirology Case Reports, Volume 13, Issue 5, May 2025.
Here, we report our treatment experience of a patient with critically severe empyema on extracorporeal membrane oxygenation (ECMO) and subsequent complex treatments, ultimately resulting in his recovery. ABSTRACT Empyema is one of the most dangerous complications in thoracic surgery.
Shunxin Xin, Zhongliang He, Weihua Xu, Xueming He, Guoxing Chen, Zhongrui Ye, Xia Hong   +6 more
wiley   +1 more source

Mycobacterium abscessus Complex Infections Among Lung Transplant Recipients: A Multicenter Retrospective Cohort Study in Canada

Transplant Infectious Disease, Volume 27, Issue 3, May/June 2025.
Posttransplant Mycobacterium abscessus infection occurred in 53% of patients with pretransplant infection. While pretransplant infection itself was not associated with impaired survival, both failure to achieve microbiological eradication before transplant and persistent posttransplant disease were linked to increased mortality.
Roni Bitterman, Hafid Soualhine, Pierre‐Marie Akochy, Charles Poirier, Pasquale Ferraro, Dima Kabbani, Alim Hirji, Gregory Tyrrell, Celine Bergeron, Robert D. Levy, Alissa Wright, Victor Leung, Lianne G Singer, Cecilia Chaparro, Shaf Keshavjee, Melissa Richard‐Greenblatt, Shahid Husain, Me‐Linh Luong   +17 more
wiley   +1 more source

Safety of Omadacycline Versus Standard-of-Care Oral Antibiotic Treatment for Bone and Joint Infections: Interim Results from an Open-Label, Non- Inferiority, Randomized Controlled Trial [PDF]

Background The incidence of bone and joint infections (BJIs) continues to increase, and existing oral BJI antibiotics have limitations. Omadacycline may be a potential treatment option for BJI treatment due to activity against doxycycline-resistant S ...
Delgado, Guarina Garcia, Flores, Evelyn A., Kang, Amy Y., Miller, Loren G., Payan, Isabel, Romo-Kozan, Vanessa, Tran, Donna Phan   +6 more
core   +2 more sources

In Vitro Antimicrobial Activities of Tigecycline, Eravacycline, Omadacycline, and Sarecycline against Rapidly Growing Mycobacteria

Microbiology Spectrum, 2023
Infections caused by rapidly growing mycobacteria (RGM) have increased globally. Chemotherapy against these infections is challenging due to the minimal antimicrobial choices available.
Tingting Zhang, Jian Du, Lingling Dong, Fen Wang, Liping Zhao, Junnan Jia, Congli Wang, Mengli Cheng, Xia Yu, Hairong Huang   +9 more
doaj   +1 more source

A review of antibiotic safety in pregnancy—2025 update

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 4, Page 227-237, April 2025.
Abstract Antibiotics constitute the majority of prescriptions for women during pregnancy. Common bacterial infections, including urinary tract infections, skin and soft tissue infections, and upper and lower respiratory tract infections, are expected in pregnancy, similar to the general public.
Johny Nguyen, Victoria Madonia, Christopher M. Bland, Kayla R. Stover, Lea S. Eiland, Julia Keating, Madeline Lemmon, P. Brandon Bookstaver, as part of the Southeastern Research Group Endeavor (SERGE‐45) research network   +8 more
wiley   +1 more source

In Vitro Synergistic Effects of Omadacycline with Other Antimicrobial Agents against Mycobacterium abscessus [PDF]

Nagasaki University (長崎大学)博士(医学)The clinical importance of Mycobacterium abscessus species (MABS) infections has been increasing. However, the standard treatment regimens recommended in the current guidelines often result in unfavorable outcomes ...
藤原, 啓司
core   +1 more source

Community‐Acquired Chlamydia psittaci Severe Pneumonia: A Case Report

Case Reports in Infectious Diseases, Volume 2025, Issue 1, 2025.
Chlamydia psittaci, the causative agent of psittacosis, is an intracellular bacterium typically transmitted from birds to humans, leading to atypical pneumonia. We present a case of a 60‐year‐old man with no reported bird exposure but a history of working as a chief cook, potentially exposed to poultry.
Quentin Guillemot, Thomas Clemens, Valentine Inthasot, Bhavna Mahadeb, Evelyne Maillart, Philippe Clevenbergh, Larry M. Bush   +6 more
wiley   +1 more source