Results 71 to 80 of about 1,725 (146)

Omadacycline for Diverse Infections in China: A Real-World Analysis of Efficacy and Safety

Infectious Diseases and Therapy
Introduction The efficacy and safety of omadacycline have been primarily documented through Phase III clinical trials; however, there are limited data from real-world clinical settings.
Weiwen Gao, Jian Yang, Xiangwang Zhang, Lei Tian, Dong Xu, Shuyun Xu, Dong Liu, Yan He   +7 more
doaj   +1 more source

Population Pharmacokinetic Analyses for Omadacycline Using Phase 1 and 3 Data

, 2020
Elizabeth A. Lakota, Scott A. Van Wart, Michael Trang, Evan Tzanis, Sujata M. Bhavnani, M. Courtney Safir, Lawrence V. Friedrich, Judith N. Steenbergen, Paul G. Ambrose, Christopher M. Rubino   +9 more
openalex   +1 more source

In Vivo Pharmacodynamic Evaluation of Omadacycline (PTK 0796) against Streptococcus pneumoniae in the Murine Pneumonia Model [PDF]

, 2017
Alexander J. Lepak, Miao Zhao, Karen Marchillo, Jamie VanHecker, David R. Andes   +4 more
openalex   +1 more source

In Vitro Activity of Omadacycline against Chlamydia pneumoniae [PDF]

, 2018
Stephan Kohlhoff, Natalia Huerta, Margaret R. Hammerschlag   +2 more
openalex   +1 more source

489. Bile Acid Concentrations in Healthy Volunteers Receiving Oral Omadacycline or Vancomycin

, 2022
Jinhee Jo, Chenlin Hu, Weiqun Wang, Anne J Gonzales-Luna, Chris Lancaster, Kevin W. Garey   +5 more
openalex   +1 more source

Emergence of plasmid-borne tet(X4) resistance gene in clinical isolate of eravacycline- and omadacycline-resistant Klebsiella pneumoniae ST485

Microbiology Spectrum
Omadacycline and eravacycline are gradually being used as new tetracycline antibiotics for the clinical treatment of Gram-negative pathogens. Affected by various tetracycline-inactivating enzymes, there have been reports of resistance to eravacycline and
Xiaojing Liu, Yi Liu, Xiaohan Ma, Ruyan Chen, Chenyu Li, Hongxin Fu, Yu Yang, Kexin Guo, Xiaoping Zhang, Ruishan Liu, Hao Xu, Junfei Zhu, Beiwen Zheng   +12 more
doaj   +1 more source

Fecal Pharmacokinetics and Gut Microbiome Effects of Oral Omadacycline Versus Vancomycin in Healthy Volunteers [PDF]

, 2023
Jinhee Jo, Chenlin Hu, Khurshida Begum, Weiqun Wang, Thanh Minh Le, Samantha Agyapong, Blake Hanson, Hossaena Ayele, Chris Lancaster, Mohammad Jahangir Alam, Anne J Gonzales-Luna, Kevin W. Garey   +11 more
openalex   +1 more source

Susceptibility of multidrug-resistant Escherichia coli and Klebsiella pneumoniae to oral antibiotics in Australia

Journal of Global Antimicrobial Resistance
: Objectives: In Australia, resistance to β-lactam-class antibiotics in Enterobacterales has increased. This study aimed to identify potential oral treatments for these multidrug-resistant infections by investigating four β-lactam (mecillinam, tebipenem,
Bethany Rachel O'Neill, Andrew Ginn, Menuk Jayawardena, Indy Sandaradura   +3 more
doaj   +1 more source

Evaluation of the Impact of Comorbidities on Omadacycline Pharmacokinetics

, 2023
Michael Trang, Elizabeth A. Lakota, M. Courtney Safir, Sujata M. Bhavnani, Lawrence V. Friedrich, Judith N. Steenbergen, Paul C. McGovern, Evan Tzanis, Christopher M. Rubino   +8 more
openalex   +1 more source

2577. Comparing Omadacycline with Existing Antibiotics in the treatment of Acute Bacterial Infections: A Systematic Review [PDF]

, 2023
Stephanie P Fabara, Akankcha Alok, Sripal Padam, Robert W. Yancey   +3 more
openalex   +1 more source