Results 91 to 100 of about 50,234 (263)

Proton Pump Inhibitor‐Induced Fundic Gland Polyps With Massive Bleeding Regressed on Alternative Histamine 2 Receptor Antagonist Therapy

DEN Open, Volume 6, Issue 1, April 2026.
Abstract We report a case of massive bleeding from proton pump inhibitor (PPI)‐induced fundic gland polyps (FGPs) that regressed after switching to a histamine‐2 receptor antagonist (H2RA). A 46‐year‐old man with antiphospholipid syndrome had been receiving warfarin and lansoprazole for 4 years.
Ryosuke Ikeda, Hiroaki Kaneko, Hiroki Sato, Yuto Matsuoka, Tomomi Hamaguchi, Aya Ikeda, Yoshihiro Goda, Soichiro Sue, Kuniyasu Irie, Shin Maeda   +9 more
wiley   +1 more source

Omeprazole exacerbates intervertebral disc degeneration through Caspase-3 mediated apoptosis of nucleus pulposus cells: a Mendelian randomization, network toxicology, and in vitro experimental study

Journal of Orthopaedic Surgery and Research
Objective To investigate the causal correlation and toxicological mechanisms of omeprazole in intervertebral disc degeneration (IVDD), alongside a particular emphasis on Caspase-3 (CASP3) mediated apoptosis of nucleus pulposus cells (NPCs).
Yuchao Jia, Haifan Zhao, Shengbo Huang, Baoshan Xu   +3 more
doaj   +1 more source

Preanaesthetic oral ranitidine, omeprazole and metoclopramide for modifying gastric fluid volume and pH [PDF]

, 1994
Satinder Gombar, Shashi Kiran, Mahesh Gupta, K. K. Gombar, Balbir Chhabra   +4 more
openalex   +1 more source

Ximenia americana L. From Popular Use to Anti‐Inflammatory Activities: A Comprehensive Review

Food Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT Ximenia americana (L.), known as “yellow plum,” “sea lemon,” or “Brazilian plum,” is a tropical/subtropical plant widely used in traditional medicine. Its roots, leaves, flowers, stem, and fruits are traditionally employed to treat various inflammatory disorders.
Bruno Anderson F. Silva, Maria Gabriely de Lima Silva, Eduardo S. Silva, Lucas Yure S. Silva, Renata Torres Pessoa, Silvio C. Alves‐Júnior, Jullyana S. S. Quintans, Laurent Picot, Irwin Rose A. Menezes, Lucindo J. Quintans‐Júnior   +9 more
wiley   +1 more source

Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2

Frontiers in Microbiology, 2019
Omeprazole was shown to improve the anti-cancer effects of the nucleoside analogue 5-fluorouracil. Here, we combined omeprazole with the antiviral nucleoside analogues ribavirin and acyclovir.
Martin Michaelis, Malte C. Kleinschmidt, Denisa Bojkova, Holger F. Rabenau, Mark N. Wass, Jindrich Cinatl Jr.   +5 more
doaj   +1 more source

Serum Concentrations of Gastrin after Famotidine and Omeprazole Administration to Dogs

Journal of Veterinary Internal Medicine, 2014
Background The duration of antacid‐induced hypergastrinemia after cessation of administration of omeprazole and famotidine apparently has not been determined in dogs.
N. Parente, N. B. Olivier, K. Refsal, Cheri A. Johnson   +3 more
semanticscholar   +1 more source

Identifying Drugs Associated With Parkinson's Disease Risk Using Machine Learning

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Machine learning (ML)–based methods have been proposed as a potential approach for identifying candidate drugs to be repurposed as disease‐modifying treatments for Parkinson's disease (PD). We applied an ML‐based signal detection method to identify drugs associated with PD and evaluated the method's generalizability.
Eeva Pylkkö, Émeline Courtois, Anne Paakinaho, Sirpa Hartikainen, Valtteri Kaasinen, Alexis Elbaz, Anne C. M. Thiébaut, Ismaïl Ahmed, Anna‐Maija Tolppanen   +8 more
wiley   +1 more source

CYP2C19 genotype testing for clopidogrel: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 329-347, February 2026.
Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo, Iain Frater, Rebecca Kuruvilla, Stefanie Lip, Hannah O'Neill, Kerry Burke, Vicky Chaplin, Alexander S. F. Doney, Salim Elyas, Nicholas Greaves, Sophie Harding, David Hargroves, Judith Hayward, Dyfrig A. Hughes, Tom A. T. Hughes, Sree Kondapally, Patrick Mok, Aaron Peace, Imran Rafi, Simon Ray, Vicky Stinton, Luigi Venetucci, Munir Pirmohamed   +22 more
wiley   +1 more source

Appropriateness of Omeprazole Prescribing in Quebec’s Senior Population

Canadian Journal of Gastroenterology, 2000
BACKGROUND: Prescribing omeprazole for the treatment of digestive disorders accounts for an important part of the costs in Quebec’s drug benefit plan. In July 1993, the Quebec drug program listed omeprazole, with restriction, in its formulary. On January
Jean-Pierre Grégoire, Jocelyne Moisan, Isabelle Chabot, Michel Gaudet   +3 more
doaj   +1 more source

Gastric acidity and acid breakthrough with twice‐daily omeprazole or lansoprazole [PDF]

, 2000
Katz, Hatlebakk, Castell
openalex   +1 more source