Results 91 to 100 of about 24,384 (185)

Assessment of toxicity and oxidative stress associated with omeprazole in Caenorhabditis elegans

Acta Scientiarum: Biological Sciences
Omeprazole is an inhibitor of the proton pump which has been extensively studied presently due to the evidence of a potential toxicity related to the generation of reactive species of oxygen (ROS) to its chronic users.
Gabriela Endres da Rocha Pompeo, Roberta Rodrigues Zorzo, Bianca Bordignon Fraga, Mariele Feiffer Charão, Magda Susana Perassolo   +4 more
doaj   +1 more source

Trastuzumab Deruxtecan‐Induced Pneumonitis: Case Series

Clinical Case Reports, Volume 14, Issue 3, March 2026.
Three women with HER2‐positive metastatic breast cancer developed pneumonitis or interstitial lung disease after 2–9 cycles of trastuzumab deruxtecan. Presentations ranged from mild cough to CT‐confirmed ILD, often requiring corticosteroids and treatment interruption or discontinuation.
Abeer Alhuthali, Bushra Alqurashi, Yusra Banoun, Ziyad Almuylibi, Haneen Sait, Bayader Al‐Sobhi, Mohammed Alnuhait   +6 more
wiley   +1 more source

Pneumatosis Cystoides Intestinalis Mimicking Perforation in a Patient With Gastric Signet Ring Cell Carcinoma: A Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Pneumatosis cystoides intestinalis (PCI) poses a diagnostic challenge by radiographically mimicking surgical emergencies like perforation. This case highlights that while PCI itself may be benign, the decision for exploration must weigh the risk of missing a life‐threatening condition or a coincident malignancy.
Yongshuai Lin, Weimin Wu, Xin Zhao, Jun Wang, Juan Yang   +4 more
wiley   +1 more source

Experience With Surgical Correction of Retrocaval Ureter: A Report of Two Cases From Northern Tanzania

Clinical Case Reports, Volume 14, Issue 3, March 2026.
Two adults with flank pain were diagnosed with a retrocaval ureter on CT showing a characteristic fishhook deformity and hydroureteronephrosis. Open pyeloureterostomy with anterior ureteral transposition resulted in an uneventful recovery and preserved renal function.
Donald Dominick Lema, Bartholomeo Nicholaus Ngowi, Frank Bright, Zerra Israel Cheyo, Phinihas Jackson Mwijumbe, Fredrick Anselim Kimaro, Musa Raymond Majura, Orgeness Jasper Mbwambo   +7 more
wiley   +1 more source

From Diagnostic Challenge to Clinical Success: Rapid Multiplex PCR Identification of Cryptosporidium in HIV‐Associated Refractory Diarrhea: A Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Cryptosporidiosis remains a challenge in people with HIV despite its decreased incidence in developed countries. We report a case of severe diarrhea in a person with HIV where Gram stain findings prioritized cryptosporidium in the differential diagnosis.
Yudai Kono, Mayu Arase, Kohei Ukai, Keiko Soneda, Shinya Yamamoto, Kazuhiko Ikeuchi, Eisuke Adachi, Yusuke Nomura, Yoshimi Higurashi, Shinji Izumiyama, Kazuki Honjo, Yu Miyakawa, Sozaburo Ihara, Hiroyuki Abe, Mitsuhiro Fujishiro, Shu Okugawa, Takeya Tsutsumi   +16 more
wiley   +1 more source

Activity of Fluoroquinolones and Proton Pump Inhibitors against Resistant Oral Bacterial Biofilms, in silico and in vitro Analysis

Polish Journal of Microbiology
Oral bacterial infections are a great health concern worldwide especially in diabetic patients. Emergence of antimicrobial resistance with reference to biofilms in oral cavity is of great concern.
Kamran Muhammad, Raza Muhammad, Ullah Riaz, Alotaibi Amal, Bano Ràheela, Zaman Ali, Chaman Sadia, Iqbal Kashif, Rasool Shahid, Amin Adnan   +9 more
doaj   +1 more source

Ximenia americana L. From Popular Use to Anti‐Inflammatory Activities: A Comprehensive Review

Food Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT Ximenia americana (L.), known as “yellow plum,” “sea lemon,” or “Brazilian plum,” is a tropical/subtropical plant widely used in traditional medicine. Its roots, leaves, flowers, stem, and fruits are traditionally employed to treat various inflammatory disorders.
Bruno Anderson F. Silva, Maria Gabriely de Lima Silva, Eduardo S. Silva, Lucas Yure S. Silva, Renata Torres Pessoa, Silvio C. Alves‐Júnior, Jullyana S. S. Quintans, Laurent Picot, Irwin Rose A. Menezes, Lucindo J. Quintans‐Júnior   +9 more
wiley   +1 more source

A Case of Lisinopril‐Induced Hallucinations

Journal of General and Family Medicine, Volume 27, Issue 2, March 2026.
ABSTRACT Background Lisinopril is generally well tolerated, but rare neuropsychiatric adverse effects have been reported. Case We describe an 89‐year‐old woman who developed vivid nocturnal auditory and visual hallucinations approximately 3 months after starting lisinopril for hypertension.
Jack Golder, Julia Isom
wiley   +1 more source

Systematic Identification of Molecular Signatures Dictating Therapeutic Effects of Clinically First‐Line Chemotherapy Regimens for Human Gastric Cancer Patients Based on Organoid Model

MedComm, Volume 7, Issue 3, March 2026.
Chemotherapy is the mainstay in the treatment of advanced gastric cancer (GC); yet, GC showed diverse responses to first‐line chemotherapy regimens and the underlying molecular basis is still not clear. Here, we established a system that combined organoid‐based chemotherapy regimen screening and transcriptome‐based evaluation to identify underlying ...
Jingwei Yang, Shuyue Qi, Yuan Gao, Jiansen Lu, Lin Deng, Xinglong Wu, Yifei Zhao, Yun Liu, Yanpeng Ma, Jiagui Song, Lixiang Xue, Lu Wen, Wei Fu, Fuchou Tang, Xin Zhou   +14 more
wiley   +1 more source

Comprehensive Pathophysiology Repository for PBPK Modeling in Liver Cirrhosis: Quantifying Continuous Disease Progression and Population Variability

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 3, March 2026.
ABSTRACT Liver cirrhosis is accompanied by pathophysiological changes. Due to multiple absorption, distribution, metabolism and excretion (ADME)‐related pathophysiological alterations, the estimation of the net pharmacokinetics (PK) change in cirrhotic patients is complex.
Annika R. P. Schneider, Vanessa Baier, Jan‐Frederik Schlender, Lars Kuepfer   +3 more
wiley   +1 more source