Results 81 to 90 of about 25,084 (213)

A combination of modified Kuhnt–Szymanowski and Celsus–Hotz techniques for correction of entropion and overlong lower eyelids in dogs (40 eyes)

open access: yesVeterinary Ophthalmology, Volume 28, Issue 2, Page 114-123, March 2025.
Abstract Purpose To describe a surgical approach to correct entropion and overlong lower eyelids in dogs by combining the Celsus–Hotz with the modified Kuhnt–Szymanowski technique. Methods Medical records of patients undergoing the described surgical procedure were reviewed.
Hanna Walter   +3 more
wiley   +1 more source

The effects of uninterrupted and interrupted sitting on blood pressure and arterial stiffness in patients with established coronary heart disease

open access: yesExperimental Physiology, EarlyView.
Abstract Sedentary behaviour is an independent risk factor for cardiovascular disease. In healthy adults, prolonged uninterrupted sitting acutely increases blood pressure (BP) and aortic stiffness; however, these effects can be mitigated with light physical activity interruptions.
Simon Fryer   +7 more
wiley   +1 more source

Platelet function in patients undergoing major non‐cardiac vascular surgery (PLUGS): a prospective cohort study*

open access: yesAnaesthesia, Volume 81, Issue 9, Page 1236-1244, September 2026.
Summary Introduction Patients who require major vascular surgery often receive antiplatelet therapy for primary or secondary prevention of cardiovascular disease. Clopidogrel resistance and variability in platelet recovery after drug discontinuation pose clinical challenges, particularly for regional anaesthesia and blood management.
Akshay Shah   +11 more
wiley   +1 more source

Surgical management of recurrent oesophageal obstruction in a yearling Saddlebred filly

open access: yesEquine Veterinary Education, Volume 38, Issue 9, Page e585-e590, September 2026.
Summary This case report describes the diagnostic approach and surgical management of a yearling Saddlebred filly with recurrent oesophageal obstruction, likely caused by an acquired extraluminal oesophageal stricture. The filly initially presented with repeated episodes of oesophageal obstruction, which were resolved with sedation and nasogastric ...
K. M. Andrews   +4 more
wiley   +1 more source

Vonoprazan pharmacokinetics and effects on gastric pH following administration to fed and fasted horses

open access: yesEquine Veterinary Journal, Volume 58, Issue 5, Page 1363-1371, September 2026.
Abstract Background Current treatment options for equine gastric ulcer syndrome (EGUS), such as omeprazole—a proton pump inhibitor (PPI)—have notable limitations, including the need for administration on an empty stomach. Potassium‐competitive acid blockers (P‐CABs), such as vonoprazan, are a newer class of acid suppressants that offer several ...
Camilo J. Morales   +4 more
wiley   +1 more source

Assessment of toxicity and oxidative stress associated with omeprazole in Caenorhabditis elegans

open access: yesActa Scientiarum: Biological Sciences
Omeprazole is an inhibitor of the proton pump which has been extensively studied presently due to the evidence of a potential toxicity related to the generation of reactive species of oxygen (ROS) to its chronic users.
Gabriela Endres da Rocha Pompeo   +4 more
doaj   +1 more source

Systemic Corticosteroids in the Management of Sinonasal Disease: An Evidence‐Based Expert Review

open access: yesInternational Forum of Allergy &Rhinology, Volume 16, Issue 8, Page 852-879, August 2026.
ABSTRACT Background Chronic rhinosinusitis (CRS) is a prevalent, heterogeneous inflammatory disease associated with significant morbidity. Systemic corticosteroids (SCS) are commonly prescribed for their anti‐inflammatory effects, but cumulative exposure carries risks, including metabolic, cardiovascular, and skeletal complications.
Andrew Thamboo   +28 more
wiley   +1 more source

Development and validation of a reversed-phase HPLC-UV method for simultaneous determination of levosulpiride and omeprazole in human plasma: Applicability of the method for evaluation of pharmacokinetic drug-drug interactions.

open access: yesPLoS ONE
Levosulpiride and omeprazole are co-prescribed for gastrointestinal disorders associated with depression and anxiety. Objective of the study was to develop a sensitive, robust and simple method for simultaneous analysis of levosulpiride and omeprazole in
Muhammad Hashim   +3 more
doaj   +1 more source

Quantitative prediction of intravenous drug interactions caused by cytochromes P450 inhibitors and inducers

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2682-2692, August 2026.
Background Aims Pharmacokinetic interaction studies typically focus on oral administration, but intravenous (IV) administration bypasses intestinal degradation and hepatic first‐pass metabolism, leading to distinct drug–drug interaction (DDI) magnitude. This study aimed to develop a predictive model for DDIs involving IV‐administered drugs.
Vianney Tuloup   +2 more
wiley   +1 more source

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