Results 91 to 100 of about 34,491 (205)

Retrospective evaluation of outcomes in dogs with non‐associative immune‐mediated haemolytic anaemia treated with rivaroxaban as a sole or adjunctive thromboprophylaxis agent: 34 cases (2018‐2024)

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives To describe clinical outcomes, thromboembolic and haemorrhagic complications, and treatment characteristics in dogs with non‐associative immune‐mediated haemolytic anaemia treated with rivaroxaban at a UK referral hospital. Materials and Methods Retrospective descriptive study of dogs diagnosed with non‐associative immune‐mediated haemolytic
S. Conway, L. Jenkins, J. Reeve
wiley   +1 more source

Omeprazole induces CYP450 expression in female rats.

open access: yes, 2016
qPCR analysis of hepatic (A) Cyp 1a1, (B) Cyp 1a2, (C) Cyp 3a1, (D) Cyp 2e1, (E) Cpr and renal (F) Cyp 1a1 mRNA levels in the four rat cohorts. CTL, control; AMK, Aristolochia manshuriensis Kom; OM, omeprazole; O+A, omeprazole and AMK. Data are expressed
Aihua Liang (114552)   +10 more
core   +1 more source

In Vivo Studies on the Interaction Between Orally Administered Nitrite and Omeprazole: Beyond Proton-Catalyzed S-Nitrosation

open access: yesAntioxidants
Inorganic nitrite contributes to the nitrosation of biomolecules and exerts antioxidant effects. The proton pump inhibitor omeprazole has pro-oxidant effects, inhibits the formation of nitroso species in the stomach, and abrogates the blood pressure ...
Macario A. Rebelo   +11 more
doaj   +1 more source

Cytoprotective Actions of Omeprazole in Indomethacin – Induced Gastric Mucosal Injury in Rats.

open access: yesمجلة كلية الطب, 2010
Background: Gastric mucosal injury induced by NSAIDs is a major adverse effect of this group of medications, and it is no surprise that protection against such injury has become an important challenge for a better understanding of the mechanisms involved.
Mohammed J. Manna, Samir Y. N. Matloub
doaj   +1 more source

Long‐term outcomes following modified Blalock–Taussig–Thomas shunt placement in 13 dogs with cyanotic congenital heart disease

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives To describe long‐term outcome and owner‐perceived quality of life in dogs with cyanotic congenital cardiac disease undergoing modified Blalock–Taussig–Thomas shunt procedure. Materials and Methods Medical records of dogs that underwent Blalock–Taussig–Thomas shunt between 2009 and 2025 at a small animal referral hospital were retrospectively
M. Rossanese, J. Hannabuss, D. Brockman
wiley   +1 more source

Omeprazole ameliorates aspirin-induced gastroduodenal injury [PDF]

open access: yes, 1994
Aspirin and nonsteroidal antiinflammatory drugs (NSAIDs) damage the gastroduodenal epithelium by two mechanisms: direct toxic effects and effects related to the depletion of endogenous prostaglandins.
Behler, Elizabeth M.   +3 more
core   +1 more source

Combination of Hypofractionated Radiation Therapy and Gilvetmab for the Treatment of Cutaneous or Subcutaneous Mast Cell Tumours in Dogs

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT Gilvetmab is a caninised monoclonal antibody against canine PD‐1. Concurrent or sequential administration of anti‐PD‐1 antibodies and radiation therapy (RT) improves survival time in various species. Eighteen dogs with mast cell tumours (MCTs) were prospectively treated with 24 Gy of RT over Days 0, 7 and 21 and gilvetmab every 2 weeks ...
Tiffany W. Martin   +2 more
wiley   +1 more source

Case Report: T‐Lymphoblastic Leukemia in a Dog With Erythrophagia

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT A 2‐year‐old male German Shepherd dog was presented with progressive weight loss, lethargy, and hyporexia. Hematologic analysis revealed a moderate macrocytic normochromic anemia and moderate thrombocytopenia. Additionally, a pronounced leukocytosis was observed, characterized by 33% large lymphoid cells, marked neutrophilia with a significant
Francisca B. Lang   +7 more
wiley   +1 more source

Stereospecific analysis of omeprazole supports artemisinin as a potent inducer of CYP2C19

open access: yes, 1999
The purpose of the study was to determine the enantiomer pharmacokinetics of omeprazole and 5-hydroxy-omeprazole before and after administration of the antimalarial artemisinin to confirm artemisinin's ability to induce CYP2C19.
Mihara, K   +5 more
core  

Omeprazole of limited value in crying babies

open access: yes, 2010
OBJECTIVE: To determine the role of omeprazole treatment in crying infants under the age of 1 year in whom acid gastroesophageal reflux is suspected and to study the evidence for efficacy, prescribing behaviour and side effects of this medicine, which is
de Jong-van den Berg, Lolkje T W   +3 more
core   +1 more source

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