Results 111 to 120 of about 76,411 (309)

Omeprazole as a Novel Treatment Option for Giardiasis in Cats

open access: yesVeterinary Medicine and Science
Background Giardiasis is a common protozoal infection in cats, often treated with nitroimidazole derivatives such as metronidazole and secnidazole. However, there are concerns about resistance to nitroimidazoles and their adverse effects. Recent in vitro
Murat Kaan Durgut   +6 more
doaj   +1 more source

Cytoprotective Actions of Omeprazole in Indomethacin – Induced Gastric Mucosal Injury in Rats.

open access: yesمجلة كلية الطب, 2010
Background: Gastric mucosal injury induced by NSAIDs is a major adverse effect of this group of medications, and it is no surprise that protection against such injury has become an important challenge for a better understanding of the mechanisms involved.
Mohammed J. Manna, Samir Y. N. Matloub
doaj   +1 more source

Duodenal stricture and portal gas accumulation secondary to ulcerative, fibronecrotising duodenitis in a foal

open access: yesEquine Veterinary Education, EarlyView.
Summary Gastroduodenal ulcer disease with secondary stricture formation of the proximal duodenum and portal gas accumulation is described in a neonatal foal. Conventional diagnostics were performed to reach a diagnosis, including gastroscopy, ultrasonography and positive contrast radiography. In addition, a post‐mortem CT was acquired with the contrast
R. F. Dash   +3 more
wiley   +1 more source

Enantioselective analysis of omeprazole in pharmaceutical formulations by chiral high-performance liquid chromatography and capillary electrophoresis

open access: yesJournal of the Brazilian Chemical Society, 2004
We developed two sensitive and simple assay procedures based on high- performance liquid chromatography and capillary electrophoresis (CE) for the enantioselective analysis of omeprazole in pharmaceutical formulations.
Bonato Pierina S., Paias Fernanda O.
doaj  

Gastric pH in Rats: Key Determinant for Preclinical Evaluation of pH-dependent Oral Drug Absorption

open access: yesPrague Medical Report, 2019
Data on gastric pH in rats to be used in preclinical models for pH-dependent drug absorption are still limited or contradictory. The aim of this study was to describe gastric pH in rats at fasted state and to evaluate its changes induced by pentagastrin ...
Martin Šíma   +5 more
doaj   +1 more source

Omeprazole exacerbates intervertebral disc degeneration through Caspase-3 mediated apoptosis of nucleus pulposus cells: a Mendelian randomization, network toxicology, and in vitro experimental study

open access: yesJournal of Orthopaedic Surgery and Research
Objective To investigate the causal correlation and toxicological mechanisms of omeprazole in intervertebral disc degeneration (IVDD), alongside a particular emphasis on Caspase-3 (CASP3) mediated apoptosis of nucleus pulposus cells (NPCs).
Yuchao Jia   +3 more
doaj   +1 more source

Risk factors for hospitalization among adults with asthma: the influence of sociodemographic factors and asthma severity. [PDF]

open access: yes, 2001
BackgroundThe morbidity and mortality from asthma have markedly increased since the late 1970s. The hospitalization rate, an important marker of asthma severity, remains substantial.MethodsIn adults with health care access, we prospectively studied 242 ...
Blanc, PD   +4 more
core  

Appropriateness of Omeprazole Prescribing in Quebec’s Senior Population

open access: yesCanadian Journal of Gastroenterology, 2000
BACKGROUND: Prescribing omeprazole for the treatment of digestive disorders accounts for an important part of the costs in Quebec’s drug benefit plan. In July 1993, the Quebec drug program listed omeprazole, with restriction, in its formulary. On January
Jean-Pierre Grégoire   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy