Results 131 to 140 of about 34,491 (205)

Frequency of Clinically Relevant Drug–Drug Interactions Between Tyrosine Kinase Inhibitors and Proton Pump Inhibitors in Patients With Cancer Using Real‐World Data

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 5, November 2026.
ABSTRACT Background Proton pump inhibitors (PPIs) raise stomach pH, leading to reduced bioavailability of many tyrosine kinase inhibitors (TKIs), thereby affecting treatment outcomes. To what extent this interaction occurs in clinical practice remains underexplored.
Grietje van Elp, Maikel Borg, Jens H. J. Bos, Catharina C. M. Schuiling‐Veninga, Katja Taxis, Frank G. A. Jansman   +5 more
wiley   +1 more source

Activity of Fluoroquinolones and Proton Pump Inhibitors against Resistant Oral Bacterial Biofilms, in silico and in vitro Analysis

Polish Journal of Microbiology
Oral bacterial infections are a great health concern worldwide especially in diabetic patients. Emergence of antimicrobial resistance with reference to biofilms in oral cavity is of great concern.
Kamran Muhammad, Raza Muhammad, Ullah Riaz, Alotaibi Amal, Bano Ràheela, Zaman Ali, Chaman Sadia, Iqbal Kashif, Rasool Shahid, Amin Adnan   +9 more
doaj   +1 more source

Retrospective comparison of treatments for equine gastric ulceration syndrome and the influence of inflammatory bowel disease

Equine Veterinary Education, Volume 38, Issue 11, Page e882-e891, November 2026.
Summary Background Equine squamous gastric disease (ESGD) and equine glandular gastric disease (EGGD) can be treated with oral omeprazole, combined with sucralfate or an extended‐release intramuscular omeprazole (ERIO). Objectives To evaluate these different treatments for ESGD and EGGD and assess the influence of inflammatory bowel disease (IBD) on ...
L. C. Kranenburg, C. Ludin, D. A. van Doorn, M. M. Sloet van Oldruitenborgh‐Oosterbaan, P. Witt, R. M. A. C. Houben, R. van den Boom   +6 more
wiley   +1 more source

Feasibility of Enucleation in Standing Sedated Horses With Retrobulbar Anesthesia and Auriculopalpebral Nerve Block: Impact of Ultrasound Guidance in a Case Series

Veterinary Ophthalmology, Volume 29, Issue 6, November 2026.
ABSTRACT Objective Examining the feasibility of enucleation in standing sedated horses with dorsal retrobulbar anesthesia (RBA) and auriculopalpebral (AP) nerve block and the impact of ultrasound (US) guidance on RBA success. Animals Studied Thirty horses.
Simona Lieberth, Katharina Thieme, Christian Dancker, Roswitha Merle, Johanna Corinna Eule   +4 more
wiley   +1 more source

The Metabolism and Pharmacokinetics of Omeprazole in Relation to CYP2C19 [PDF]

Omeprazole is one of the most widely used proton pump inhibitors for the treatment of gastric acid-related disorders. Omeprazole is completely metabolized, predominantly to 5-hydroxyomeprazole catalyzed by CYP2C19, which shows genetically determined ...
宇野, 司, Uno, Tsukasa
core  

Clinical characteristics of immediate allergic adverse reactions to intravenous amoxicillin‒clavulanic acid in conscious dogs

Veterinary Record, Volume 199, Issue 9, Page e423-e429, 31 October/7 November 2026.
Abstract Background Amoxicillin‒clavulanic acid (AMC) is one of the most frequently used antibiotics in small animal practice, and reports on adverse reactions are scarce. The aim of this study was to describe the clinical characteristics of immediate allergic adverse reactions to intravenous (IV) AMC in conscious dogs. Methods The medical records of a
Leonel Frutuoso, Anna Threlfall
wiley   +1 more source

Effect of omeprazole on gallbladder contraction in humans

, 2000
Background/Aims: Omeprazole causes hypergastrinemia because of the effects of prolonged complete suppression of acid secretion and also gastrin has an excitatory effect on gallbladder contraction.
Cihanyurdu, N, Cetiner, M, Baki, AH, Arslan, M, Kapicioglu, S   +4 more
core  

A complementary dual-platform analytical strategy for resolving matrix effects and stability limitations in bioanalysis. [PDF]

Front Vet Sci
Han JM, Yoon J, Kwak YB.
europepmc   +1 more source

Cost-effectiveness analysis of omeprazole for preventing esophageal stricture in patients with Zargar grade 2b and 3a corrosive esophageal injuries: A trial-based economic evaluation. [PDF]

Medicine (Baltimore)
Mahawongkajit P, Orrapin S, Tomtitchong P, Havanond C.   +3 more
europepmc   +1 more source

A phase 1 randomized study evaluating the effect of omeprazole on the pharmacokinetics of a novel 5-hydroxytryptamine receptor 4 agonist, revexepride (SSP-002358), in healthy adults

, 2015
David Pierce,1 Mary Corcoran,2 Maria Velinova,3 Stuart Hossack,4 Mieke Hoppenbrouwers,5 Patrick Martin,21Shire, Basingstoke, UK; 2Shire, Wayne, PA, USA; 3PRA International, Zuidlaren, the Netherlands; 4Covance, Leeds, UK; 5Shire-Movetis NV, Turnhout ...
Velinova M, Hossack S, Hoppenbrouwers M, Pierce D, Martin P, Corcoran M   +5 more
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