Results 101 to 110 of about 34,491 (205)

A combination of modified Kuhnt–Szymanowski and Celsus–Hotz techniques for correction of entropion and overlong lower eyelids in dogs (40 eyes)

open access: yesVeterinary Ophthalmology, Volume 28, Issue 2, Page 114-123, March 2025.
Abstract Purpose To describe a surgical approach to correct entropion and overlong lower eyelids in dogs by combining the Celsus–Hotz with the modified Kuhnt–Szymanowski technique. Methods Medical records of patients undergoing the described surgical procedure were reviewed.
Hanna Walter   +3 more
wiley   +1 more source

Omeprazole exacerbates intervertebral disc degeneration through Caspase-3 mediated apoptosis of nucleus pulposus cells: a Mendelian randomization, network toxicology, and in vitro experimental study

open access: yesJournal of Orthopaedic Surgery and Research
Objective To investigate the causal correlation and toxicological mechanisms of omeprazole in intervertebral disc degeneration (IVDD), alongside a particular emphasis on Caspase-3 (CASP3) mediated apoptosis of nucleus pulposus cells (NPCs).
Yuchao Jia   +3 more
doaj   +1 more source

The effects of uninterrupted and interrupted sitting on blood pressure and arterial stiffness in patients with established coronary heart disease

open access: yesExperimental Physiology, EarlyView.
Abstract Sedentary behaviour is an independent risk factor for cardiovascular disease. In healthy adults, prolonged uninterrupted sitting acutely increases blood pressure (BP) and aortic stiffness; however, these effects can be mitigated with light physical activity interruptions.
Simon Fryer   +7 more
wiley   +1 more source

Role of CYP3A4 in the regulation of the aryl hydrocarbon receptor by omeprazole sulphide

open access: yes, 2006
Cross-talk between nuclear receptors involved in the control of drug metabolism is being increasingly recognised as a source of drug side effects. Omeprazole is a well known activator of the aryl hydrocarbon receptor (AhR). We investigated the regulation
Gerbal-Chaloin, S   +6 more
core   +1 more source

Endoscopic Removal of a Toothpick Penetrating the Gastric Wall and Extending Into the Head of the Pancreas: A Case Report and Brief Literature Review

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Ingested toothpicks can perforate the gastrointestinal tract and penetrate adjacent organs. Pancreatic involvement is rare, and its management varies between surgical and endoscopic interventions. We report the successful endoscopic removal of a toothpick that penetrated the gastric wall and extended into the head of the pancreas.
Ken Nakayama   +9 more
wiley   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

open access: yesArthritis Care &Research, Volume 78, Issue 11, Page 1618-1630, November 2026.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel   +6 more
wiley   +1 more source

Inhibitor effect of omeprazole in isolated human myometrial smooth muscle

open access: yes, 2001
The aim of the present study was to investigate the effect of omeprazole, an H+-K+-ATPase inhibitor, in myometrial smooth muscle strips from women undergoing elective caesarean section at term.
Sarioglu, Y   +5 more
core   +1 more source

The quantification and epistemology of medicines use and polypharmacy tested in an observational study

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3850-3861, November 2026.
Definitions of ‘medicines use’ and ‘polypharmacy’ may refer to all medicines, regular long‐term medicines or another subset. Valid definitions of medicines use should incorporate type of use (long term, short course and as needed [PRN]), changes in use (start, stop and dose change) and a description of temporal examination (cross‐sectional or ...
Lorna Pairman, Paul Chin, Matthew Doogue
wiley   +1 more source

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