Results 61 to 70 of about 30,804 (255)

Role of Omeprazole as An Antifungal Agent [PDF]

, 2011
The antifungal activity of various concentrations of omeprazole (0.1mg/ml, 0.25mg/ml, 0.5mg/ml, 1mg/ml, 2.5mg/ml, 5mg/ml, 10mg/ml, and 20mg/ml) were studied in different pH media (5 and 7) against Aspergillus niger, and Trichophyton urbrum.The laboratory
Ali A. Juwaied, Omar A. Al-Mukhtar, Suhad A. Ahmad, Raya R. Jabri   +3 more
core   +1 more source

Evaluation of a pantoprazole and 4‐desmethylpantoprazole‐sulfate metabolic ratio as a novel CYP2C19 phenotyping method

British Journal of Clinical Pharmacology, EarlyView.
Aims CYP2C19 is one of the most important pharmacogenes, and its activity is highly variable due to factors such as genetics or drug–drug interactions. Due to the lack of an appropriate endogenous CYP2C19 biomarker, surrogate methods to assess its activity are warranted.
Julian Peter Müller, Vladimir N. Belov, Sabrina Yamoune, Bob Miller, Mohammed Hasoumi, Jolanta Tupiec, Thea Laurentius, L. Cornelius Bollheimer, Julia C. Stingl, Katja S. Just   +9 more
wiley   +1 more source

Plasma Exosome Metabolomics Reveal Stage‐Specific Alterations in Elderly Women With Premetabolic and Metabolic Syndrome

Chronic Diseases and Translational Medicine, EarlyView.
Shared differential metabolites identified across the three sample groups. (A) Venn diagram of differential metabolites between the two comparison groups; Based on the detected levels of these overlapping differential metabolites, (B) d‐Arabitol, (C) Triclosan, (D) Iloprost, (E) Tetracosanoic acid, and (F) Omeprazole sulfone. Box plots were constructed
Mengtao Qian, Dan Nie, Qianyi Gao, Xingbo Mo, Huan Zhang   +4 more
wiley   +1 more source

Omeprazol sódico: caracterização das propriedades físico-químicas e desenvolvimento de comprimidos gastro-resistentes [PDF]

, 2009
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Farmácia.O omeprazol é o fármaco de primeira escolha para o tratamento de desordens ácido-pépticas.
Murakami, Fábio Seigi
core  

Urine metabolic ratio of omeprazole in relation to CYP2C19 polymorphisms in Russian peptic ulcer patients

, 2017
Natalia P Denisenko,1–3 Dmitriy A Sychev,2 Zhanna M Sizova,3 Valeriy V Smirnov,4,5 Kristina A Ryzhikova,1 Zhannet A Sozaeva,1 Elena A Grishina1 1Research Center, Russian Medical Academy of Continuous Professional Education, Ministry of Healthcare ...
Valeriy Smirnov, Ryzhikova KA, Sychev DA, Sizova ZM, Dmitriy Sychev, Denisenko NP, Kristina Ryzhikova, Elena Grishina, Natalia Denisenko, Smirnov VV, Sozaeva ZA, Grishina EA, Zhanna Sizova, Zhannet Sozaeva   +13 more
core   +1 more source

Irrational Prescribing Habit of Omeprazole

, 2020
The primary aim of the study is to examine the frequency of omeprazole prescription from all the prescriptions received by a pharmacist in a single day. Besides, the author examines the cost of dispensed omeprazole.
Elham Alshammari
core   +1 more source

CYP2C19 Genotype is Associated with Citalopram Treatment Outcomes in a Real‐World Setting

Clinical Pharmacology &Therapeutics, EarlyView.
CYP2C19 metabolizes various selective serotonin reuptake inhibitors (SSRIs) and genetic CYP2C19 variants are associated with SSRI tolerability and response. Yet, whether CYP2C19 variability also impacts citalopram response remained unclear. We here evaluated associations between CYP2C19 genotypes and citalopram prescription data of 11,079 patients from
Yoomi Park, Yitian Zhou, Volker M. Lauschke   +2 more
wiley   +1 more source

Impact of obesity and roux‐en‐Y gastric bypass on the pharmacokinetics of (R)‐ and (S)‐omeprazole and intragastric pH

CPT: Pharmacometrics & Systems Pharmacology
This study employed physiologically‐based pharmacokinetic–pharmacodynamics (PBPK/PD) modeling to predict the effect of obesity and gastric bypass surgery on the pharmacokinetics and intragastric pH following omeprazole treatment.
Leandro F. Pippa, Valvanera Vozmediano, Lieke Mitrov‐Winkelmolen, Daan Touw, Amira Soliman, Rodrigo Cristofoletti, Wilson Salgado Junior, Natalia Valadares de Moraes   +7 more
doaj   +1 more source

Plasma and Urine Pharmacokinetics of Long-Acting Injectable Omeprazole Following Intramuscular Administrations to Healthy Thoroughbred Horses

Omeprazole is a gastric acid secretion inhibitor used as an effective anti-ulcer drug. Based on oral administration studies, its International Screening Limit (ISL) was established in plasma and urine at 1 ng/mL with a Detection Time (DT) of 48 h.
Harding, Caitlin, Paine, Stuart W., Habershon-Butcher, Jocelyn, Viljanto, Marjaana, Hincks, Pamela   +4 more
core   +1 more source

Artemisinin induces omeprazole metabolism in human beings

, 1998
Objective: This study investigated whether time-dependent artemisinin pharmacokinetics correlated to CYP3A4 or CYP2C19 activity in vivo. Methods: Artemisinin (two oral doses per day of 250 mg) was given to nine healthy Vietnamese subjects for 7 days (day
Van Huong, Nguyen, Nieu, N T, Huong, DX, Lykkesfeldt, Jens, Hai, Trinh Ngoc, Bertilsson, Leif, Cong, L D, Bertilsson, L,, Công, LD, Sy, N D, Công, Le Dinh, Huong, NV, Hai, T N, Huong, Dinh Xuan, Ashton, M, Nieu, NT, Svensson, Ulrika S H,, Sy, ND, Huong, D X, Niêu, Nguyen Thi, Ashton, Michael, Bertilsson, L, Lykkesfeldt, J, Sy, Nguyen Duy, Van Huong, N, Svensson, USH, Hai, TN, Svensson, Ulrika S.H.   +27 more
core   +1 more source