Results 41 to 50 of about 30,804 (255)

ENHANCEMENT OF THE ANTIDIABETIC EFFECT OF GLICLAZIDE BY THE ANTIPEPTIC DRUG OMEPRAZOLE IN ALLOXAN-INDUCED DIABETIC RATS [PDF]

open access: yesAssiut Veterinary Medical Journal, 2019
Introduction: Diabetes mellitus (DM) is a global emerging disease with progressive incidence worldwide. Diabetic patients have a higher incidence of peptic ulcer disease than the non-diabetic population.
MAHMOUD ABDELRAHIM   +2 more
doaj   +1 more source

THE EFFECT OF OMEPRAZOLE ON TREATMENT OUTCOMES IN PATIENTS WITH SEVERE TRAUMATIC BRAIN INJURY AND SEPSIS

open access: yes, 2020
Background. The interrelation between omeprazole use and the possibility of developing nosocomial pneumonia, acute kidney damage and Clostridium difficile-induced diarrhea in patients with sepsis requires further study. Material and methods.
Oliynyk, O.   +2 more
core   +1 more source

Study on the Preparation Technology of Omeprazole Vesicles [PDF]

open access: yes, 2021
Herein a study on the process of converting omeprazole into omeprazole vesicles by a film dispersion method is presented. Using encapsulation efficiency as an index, the formulation and technology of omeprazole vesicles are optimized by a single factor ...
Wang, Zhimei   +5 more
core   +1 more source

A Biomimetic Lubricant Captures Hyaluronic Acid In Situ to Regenerate Cartilage: From Bench to Bedside

open access: yesAdvanced Science, EarlyView.
(a) The outstanding lubricative properties of natural articular cartilage arise from a composite coating composed of HA, lubricin, and phospholipids at its surface. Notably, lubricin facilitates the enrichment of synovial HA onto cartilage surfaces, and HA complexes with phospholipids, a key component to maintain extremely low friction under high ...
Yongan Lin   +12 more
wiley   +1 more source

Low Helicobacter pylori eradication rates with 4- and 7-day regimens in an Iranian population [PDF]

open access: yes
Background: In Iran, there is insufficient information on the efficacy of Helicobacter pylori eradication regimens shorter than 10 days. This study aims at assessing the efficacy of 4- and 7-day H. pylori eradication regimens in a high-incidence area of
میکاییلی, جواد   +15 more
core   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

open access: yesAdvanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai   +7 more
wiley   +1 more source

Omeprazole and Risk of Hypertension: Analysis of Existing Literature and the WHO Global Pharmacovigilance Database

open access: yesDrugs - Real World Outcomes
Introduction The association between omeprazole and hypertension is poorly documented. The summary of product characteristics of omeprazole approved by major regulators did not mention hypertension as an adverse drug event.
Merhawi Bahta   +4 more
doaj   +1 more source

CSF omeprazole concentration and albumin quotient following high dose intravenous omeprazole in dogs. [PDF]

open access: yes, 2019
peer reviewedClinical signs of syringomyelia and hydrocephalus occur secondary to cerebrospinal fluid (CSF) accumulation within the central nervous system.
Girod, M   +10 more
core   +1 more source

Melatonin Levels in 89 Individuals With Smith Magenis Syndrome

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT In patients with Smith–Magenis syndrome (SMS), an inverted circadian rhythm of melatonin (MT) contributes to the sleep disturbance. Standard treatment of sleep disturbance with MT often leads to extremely high daytime MT levels, resulting in even more sleep disorders. We therefore retrospectively evaluated the MT data of 89 SMS patients.
Wiebe Braam, Ann C. M. Smith
wiley   +1 more source

Binding of omeprazole to protein targets identified by monoclonal antibodies.

open access: yesPLoS ONE, 2020
Omeprazole is the most commonly used proton pump inhibitor (PPI), a class of medications whose therapeutic mechanism of action involves formation of a disulfide linkage to cysteine residues in the H+/K+ ATPase pump on gastric secretory cells.
Naw May Pearl Cartee, Michael M Wang
doaj   +2 more sources

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