Results 21 to 30 of about 30,804 (255)

Omeprazole treatment manifests anxiolytic effects in a cysteamine hydrochloride induced mouse model of gastrointestinal disorder

Heliyon, 2022
Omeprazole, a proton pump inhibitor (PPI), has widely been used to treat various gastrointestinal (GI) disorders. Notably, many clinical symptoms of GI disorders have been known to be associated with anxiety.
Harini Sri Rethinavel, Divya Bharathi Selvaraj, Sathya Jeevitha Balakrishnan, Jemi Feiona Vergil Andrews, Jerly Helan Mary Joseph, Mahesh Kandasamy   +5 more
doaj   +1 more source

Reno-protective Role of Ginseng in Counteracting the Long-term Omeprazole Induced Adverse Effects in Albino Rats via Modulation of Inflammation, Apoptosis and Fibrosis [PDF]

Minia Journal of Medical Research, 2023
Background: Omeprazole has long-term use adverse effects even though is commonly used. Aim: Evaluation of the possible renal protective effect of ginseng against the long-term omeprazole-induced adverse effects.
Dina Maher, Nashwa El-Tahawy, Azza Hussien, Ahmed Mahmoud   +3 more
doaj   +1 more source

Effect of Laparoscopic Sleeve Gastrectomy on the Pharmacokinetics of Oral Omeprazole Using a Population Approach

Pharmaceutics, 2022
Omeprazole is commonly prescribed to obese patients and patients after laparoscopic sleeve gastrectomy (LSG). The pharmacokinetics of oral omeprazole after LSG are still unknown. Therefore, the aim of this study was to investigate the pharmacokinetics of
Kaifeng Chen, Ping Luo, Shaihong Zhu, Yaqi Lin, Nan Yang, Shuqi Huang, Qin Ding, Liyong Zhu, Qi Pei   +8 more
doaj   +1 more source

Omeprazole physiological based pharmacokinetics model (PBPK)

, 2021
This repository provides the omeprazole physiological based pharmacokinetics/pharmacodynamics model (PBPK/PD). If you have any questions or problems please open an issue FundingMatthias König is supported by the Federal Ministry of Education and Research
Balci, Sükrü, König, Matthias
core   +1 more source

Omeprazole Prevents Colistin-Induced Nephrotoxicity in Rats: Emphasis on Oxidative Stress, Inflammation, Apoptosis and Colistin Accumulation in Kidneys

Pharmaceuticals, 2022
The clinical value of colistin, a polymyxin antibiotic, is limited by its nephrotoxicity. Omeprazole is a commonly prescribed proton pump inhibitor.
Mohammed Z. Nasrullah, Khalid Eljaaly, Thikryat Neamatallah, Usama A. Fahmy, Abdulmohsin J. Alamoudi, Hussain T. Bakhsh, Ashraf B. Abdel-Naim   +6 more
doaj   +1 more source

Omeprazole-induced galactorrhea in kidney transplant patients—a case report

Journal of Medical Case Reports, 2022
Background Omeprazole belongs to the pharmacological classifications of proton pump inhibitors and is a widely used medicine. All proton pump inhibitors have a common mechanism of action and are prodrugs that require activation in an acidic environment ...
Choki Dorji, Farruk Ahammed Robin, Kesara Na-Bangchang   +2 more
doaj   +1 more source

Comparison of omeprazole, metronidazole and clarithromycin with omeprazole/amoxicillin dual-therapy for the cure of Helicobacter pylori infection [PDF]

, 1998
In this randomized, multicenter trial, we evaluated the effectiveness and side effect profile of a modified omeprazole-based triple therapy to cure Helicobacter pylori infection.
Miehlke, Stephan, Bolle, Karl-Heinz, Lehn, Norbert, Höchter, Wilhelm, Klann, Hermann, Krämer, Walter, Simon, Thomas, Stolte, Manfred, Meining, Alexander, Sommer, Albrecht, Bayerdörffer, Ekkehard, Weingart, Josef   +11 more
core   +1 more source

Occupational contact allergy to omeprazole and ranitidine [PDF]

, 2017
Omeprazole is a proton pump inhibition and ranitidine is an H2 histamine receptor antagonist widely used in the treatment of gastroesophageal reflex disease, peptic ulcer disease, Zollinger-Ellison syndrome and as a protector of the gastric mucosae.
Martí Amengual, Gabriel, Sanz-Gallen, Pere, Herrera Mozo, Inmaculada, Pere Sanz-Gallen, Sanz Gallén, Pere, Gabriel Martí-Amengual, Martí-Amengual, Gabriel, Inmaculada Herrera-Mozo, Herrera-Mozo, Inmaculada   +8 more
core   +1 more source

A case study of AstraZeneca’s omeprazole/esomeprazole chiral switch strategy [PDF]

, 2022
Introduction/Objective: To describe the chiral switch, an evergreening strategy used by AstraZeneca to position enantiopure esomeprazole as the new proton pump inhibitor market leader, displacing its predecessor omeprazole.Methodology: A four-stage ...
Piñeiro, Federico Jesús, Fernández Argüelles, Rogelio Alberto   +1 more
core   +1 more source

Omeprazole Treatment Enhances Nitrogen Use Efficiency Through Increased Nitrogen Uptake and Assimilation in Corn

Frontiers in Plant Science, 2019
Omeprazole is a selective proton pump inhibitor in humans that inhibits the H+/K+-ATPase of gastric parietal cells. Omeprazole has been recently shown to act as a plant growth regulator and enhancer of salt stress tolerance.
Michael James Van Oosten, Emilia Dell’Aversana, Alessandra Ruggiero, Valerio Cirillo, Yves Gibon, Pasqualina Woodrow, Albino Maggio, Petronia Carillo   +7 more
doaj   +1 more source