Results 31 to 40 of about 34,491 (205)

Early effect of oral administration of omeprazole with mosapride as compared with those of omeprazole alone on the intragastric pH

BMC Gastroenterology, 2012
Background The ideal medication for acid-related diseases should have a rapid onset of action to promote hemostasis and cause efficient resolution of symptoms.
Iida Hiroshi, Inamori Masahiko, Fujii Tetsuro, Sekino Yusuke, Endo Hiroki, Hosono Kunihiro, Nonaka Takashi, Koide Tomoko, Takahashi Hirokazu, Yoneda Masato, Goto Ayumu, Abe Yasunobu, Kobayashi Noritoshi, Kirikoshi Hiroyuki, Kubota Kensuke, Saito Satoru, Gotoh Eiji, Maeda Shin, Nakajima Atsushi   +18 more
doaj   +1 more source

Impact of fresh grape juice on the pharmacokinetics of omeprazole: results of a food–drug interaction study

Frontiers in Pharmacology
Grapes have been widely used for dietary ailments due to their attributed pharmacological activities. Resveratrol, the chief constituent of grapes, is responsible for their pharmacological benefits.
Tayyaba Iftikhar, Zafar Iqbal, Yasar Shah, Nauman Rahim Khan, Muhammad Abbas, Omer Shehzad, Fazal Hadi, Haseeba Sardar, Ali Abusharha, Maria Daglia, Maria Daglia, Haroon Khan, Haroon Khan   +12 more
doaj   +1 more source

ENHANCEMENT OF THE ANTIDIABETIC EFFECT OF GLICLAZIDE BY THE ANTIPEPTIC DRUG OMEPRAZOLE IN ALLOXAN-INDUCED DIABETIC RATS [PDF]

Assiut Veterinary Medical Journal, 2019
Introduction: Diabetes mellitus (DM) is a global emerging disease with progressive incidence worldwide. Diabetic patients have a higher incidence of peptic ulcer disease than the non-diabetic population.
MAHMOUD ABDELRAHIM, SAFWAT MANGOURA, SOTOHY SOTOHY   +2 more
doaj   +1 more source

Cu(II), Zn(II), Cd(II) and Hg(II) Complexes of Omeprazole (PPZH): Synthesis and Characterization [PDF]

, 2023
Omeprazole is a widely used proton pump inhibitor. This is used for the treatment of gasteo-oesophageal reflux diseases as well as acid induced inflammation disorders of the stomach and duodenum. In the scheme of gradual release and extended acting drugs,
Md Motiur, Mazumder, Salma , Begum, Humaira, Yeasmin, Md , Akteruzzaman   +3 more
core   +1 more source

Recurrent Neurodevelopmental Disorder Associated With a Dominant‐Negative TOP2B H63Y Variant

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT We describe a 7 year‐old boy with severe neurodevelopmental disorder, medically‐refractory epileptic encephalopathy, hyperkinetic movement disorder, hypotonia, cerebral and cerebellar atrophy and hypomyelination who was found to have a heterozygous de novo TOP2B NM_001330700.2:c.187C>T, p.(His63Tyr) variant.
Zong Yi Ha, Leticia Dinatto, Kirsten Meagher, Colleen Guimond, Jan M. Friedman, Peter C. Stirling, Millan S. Patel   +6 more
wiley   +1 more source

Exposure to CYP2C19‐metabolized drugs following acute stroke: A longitudinal cohort study to inform implementation of CYP2C19 genotype testing

British Journal of Clinical Pharmacology, EarlyView.
Aims Cytochrome P450 2C19 (CYP2C19) genotype testing is recommended to guide antiplatelet selection after ischaemic stroke and transient ischaemic attack. CYP2C19 also metabolizes several commonly prescribed non‐antiplatelet drugs. We aimed to quantify exposure to CYP2C19‐metabolized drugs in stroke patients at hospital discharge and during ...
Cleodie C. Swire, Andrew T. Lambarth, Ayesha Saleem, Daniel R. Burrage   +3 more
wiley   +1 more source

Artemisinin induces omeprazole metabolism in human beings

, 1998
Objective: This study investigated whether time-dependent artemisinin pharmacokinetics correlated to CYP3A4 or CYP2C19 activity in vivo. Methods: Artemisinin (two oral doses per day of 250 mg) was given to nine healthy Vietnamese subjects for 7 days (day
Van Huong, Nguyen, Nieu, N T, Huong, DX, Lykkesfeldt, Jens, Hai, Trinh Ngoc, Bertilsson, Leif, Cong, L D, Bertilsson, L,, Công, LD, Sy, N D, Công, Le Dinh, Huong, NV, Hai, T N, Huong, Dinh Xuan, Ashton, M, Nieu, NT, Svensson, Ulrika S H,, Sy, ND, Huong, D X, Niêu, Nguyen Thi, Ashton, Michael, Bertilsson, L, Lykkesfeldt, J, Sy, Nguyen Duy, Van Huong, N, Svensson, USH, Hai, TN, Svensson, Ulrika S.H.   +27 more
core   +1 more source

Omeprazole and Risk of Hypertension: Analysis of Existing Literature and the WHO Global Pharmacovigilance Database

Drugs - Real World Outcomes
Introduction The association between omeprazole and hypertension is poorly documented. The summary of product characteristics of omeprazole approved by major regulators did not mention hypertension as an adverse drug event.
Merhawi Bahta, Natnael Russom, Amon Solomon Ghebrenegus, Yohana Tecleab Okubamichael, Mulugeta Russom   +4 more
doaj   +1 more source

Induction of Erythrocyte Shrinkage by Omeprazole

Dose-Response, 2020
Omeprazole, a proton pump inhibitor blocks the H + /K + -ATPase channels of gastric parietal cells. It is used for the treatment of peptic ulcer. Prolonged use of omeprazole may involve in inducing anemia.
Ayesha Naveed, Kashif Jilani, Abu Bakar Siddique, Muhammad Akbar, Muhammad Riaz, Zahid Mushtaq, Muhammad Sikandar, Sajida Ilyas, Ismat Bibi, Asma Asghar, Ghulam Rasool, Muhammad Irfan   +11 more
doaj   +1 more source

Clinical relevance of pharmacogenomic information for improving prescribing practices in acutely admitted older medical patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Safe prescribing and effective medication review during acute hospitalization depends on accurate information about liver and kidney function because these organs are responsible for the elimination of most medications. While estimates for kidney function are widely used, comparable markers of hepatic drug‐metabolizing capacity are not routinely ...
Louise Westberg Strejby Christensen, Anne Kirstine Boas, Emilie Clausen, Nicoline Elers Koch, Anne Byriel Walls, Lotte Stig Nørgaard, Michael Asger Andersen, Anissa Aharaz, Rikke Lundsgaard Nielsen, Olivia Bornæs, Juliette Tavenier, Baker Nawfal Jawad, Helle Gybel Juul‐Larsen, Esben Iversen, Ove Andersen, Lona Louring Christrup, Kim Peder Dalhoff, Morten Baltzer Houlind   +17 more
wiley   +1 more source