Results 31 to 40 of about 54,811 (309)

Recent advances: rheumatology [PDF]

, 2000
No abstract ...
Madhok, R., Kerr, H., Capell, H.A.
core   +6 more sources

Effects of astragaloside IV on the pharmacokinetics of omeprazole in rats

Pharmaceutical Biology, 2019
Context: Omeprazole and astragaloside IV (AS-IV) are widely used for the treatment of gastric ulcers in China clinics. Objective: This study investigates the effects of AS-IV on the pharmacokinetics of omeprazole in rats.
Wei Liu, Guozhi Liu, Jing Liu
doaj   +1 more source

Impaired hepatic drug and steroid metabolism in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency [PDF]

, 2010
Objective: Patients with congenital adrenal hyperplasia due to P450 oxidoreductase (POR) deficiency(ORD) present with disordered sex development and glucocorticoid deficiency.
Arlt, Bebia, Chang, de Morais, Dominique Maiter, Dorota Tomalik-Scharte, Fl  ck, Fuhr, Gomes, Hannah E Ivison, Henderson, Jetter, Julia Kirchheiner, Kelley, Kirchheiner, Kranendonk, Nebert, Nicolo, Parkinson, Porter, Ribes, Sachse, Tantcheva-Po  r, Tomalik-Scharte, Uwe Fuhr, Wiebke Arlt   +25 more
core   +2 more sources

Binding of omeprazole to protein targets identified by monoclonal antibodies.

PLoS ONE, 2020
Omeprazole is the most commonly used proton pump inhibitor (PPI), a class of medications whose therapeutic mechanism of action involves formation of a disulfide linkage to cysteine residues in the H+/K+ ATPase pump on gastric secretory cells.
Naw May Pearl Cartee, Michael M Wang
doaj   +2 more sources

Changes in omeprazole pharmacokinetics in rats with diabetes induced by alloxan or streptozotocin: Faster clearance of omeprazole due to induction of hepatic CYP1A2 and 3A1

Journal of Pharmacy & Pharmaceutical Sciences, 2007
Purpose. To investigate the effect of diabetes mellitus induced by alloxan (DMIA) or streptozotocin (DMIS) on the pharmacokinetics of omeprazole in rats.
Dae Young Lee, Myung G. Lee, Hyun Sook Shin, Inchul Lee   +3 more
doaj   +1 more source

Stability and enzymatic studies with omeprazole: hydroxypropyl-β-cyclodextrin [PDF]

, 2010
The original publication is available at www.springerlink.com. A publicação original está disponível em www.springerlink.comOmeprazole (OME) exhibits low stability to light, heat and humidity.
A Hedges, B Ibach, C Salas, F Cheng, Fátima Fazão, G Zhao, H Marques, Helena Marques, L Marco, Luísa Serralheiro, M Abou-Donia, M Ahmed, M Arias, M Brewster, M Dewar, M Ruiz, Margarida Ramos, O Aleem, P Falé, P Houghton, P Mura, Paulo Salústio, R Hirlekar, S López, S Storpirtis, T Aihara, T Gubica, T Irie, T Loftsson, T Loftsson   +29 more
core   +1 more source

Early effect of oral administration of omeprazole with mosapride as compared with those of omeprazole alone on the intragastric pH

BMC Gastroenterology, 2012
Background The ideal medication for acid-related diseases should have a rapid onset of action to promote hemostasis and cause efficient resolution of symptoms.
Iida Hiroshi, Inamori Masahiko, Fujii Tetsuro, Sekino Yusuke, Endo Hiroki, Hosono Kunihiro, Nonaka Takashi, Koide Tomoko, Takahashi Hirokazu, Yoneda Masato, Goto Ayumu, Abe Yasunobu, Kobayashi Noritoshi, Kirikoshi Hiroyuki, Kubota Kensuke, Saito Satoru, Gotoh Eiji, Maeda Shin, Nakajima Atsushi   +18 more
doaj   +1 more source

Omeprazole in a Dog With Gastrinoma [PDF]

Journal of Veterinary Internal Medicine, 1997
A 9‐year‐old male German Shepherd Dog was presented with the primary complaints of vomiting, profuse watery diarrhea, anorexia, and severe weight loss. The dog developed hematemesis and melena, which were unresponsive to treatment with an H2‐receptor antagonist and a gastrointestinal protectant.
Dana Brooks, Gary L. Watson
openaire   +2 more sources

Research advancements and evaluation of multifactor‐induced murine models for gastric cancer

Animal Models and Experimental Medicine, EarlyView.
Murine models for gastric cancer. Abstract As one of the most prevalent gastrointestinal malignancies in humans, gastric cancer (GC) is often detected at an advanced stage, resulting in a poor prognosis and ranking it the fifth leading cause of cancer‐related deaths.
Yiqing Wang, Liang Zhang, Weixu Feng, Wanfeng Liu, Xiangyang Xue, Shiyu Feng   +5 more
wiley   +1 more source

Omeprazole and Risk of Hypertension: Analysis of Existing Literature and the WHO Global Pharmacovigilance Database

Drugs - Real World Outcomes
Introduction The association between omeprazole and hypertension is poorly documented. The summary of product characteristics of omeprazole approved by major regulators did not mention hypertension as an adverse drug event.
Merhawi Bahta, Natnael Russom, Amon Solomon Ghebrenegus, Yohana Tecleab Okubamichael, Mulugeta Russom   +4 more
doaj   +1 more source