Results 41 to 50 of about 54,811 (309)

Metamizole induces voriconazole metabolism and results in subtherapeutic voriconazole concentrations

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Voriconazole is extensively metabolized via cytochrome P450 (CYP) enzymes, predominantly CYP2C19 and CYP3A4. Drugs influencing the activity or expression of CYP enzymes can cause clinically relevant changes in the metabolism and voriconazole exposure. Metamizole is known to induce CYP3A4 and CYP2C19.
Simone D. Baan   +3 more
wiley   +1 more source

Induction of Erythrocyte Shrinkage by Omeprazole

open access: yesDose-Response, 2020
Omeprazole, a proton pump inhibitor blocks the H + /K + -ATPase channels of gastric parietal cells. It is used for the treatment of peptic ulcer. Prolonged use of omeprazole may involve in inducing anemia.
Ayesha Naveed   +11 more
doaj   +1 more source

Acid-suppressive effects of generic omeprazole: Comparison of three brands of generic omeprazole with original omeprazole [PDF]

open access: yesDigestive and Liver Disease, 2006
Generic omeprazole contains the same active ingredient as original omeprazole and require verification of the bioequivalence with original omeprazole. However, very few clinical studies have been reported.A prospective, randomised, open-label, crossover study to compare acid-suppressive effect of generic omeprazole with that of original omeprazole ...
Shimatani, Tomohiko   +5 more
openaire   +4 more sources

Voclosporin‐induced gingival enlargement: A case report

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background Drug‐influenced gingival enlargement (DIGE) is a recognized adverse effect of certain medications, particularly immunosuppressants like cyclosporin and tacrolimus. However, there have been no documented cases of DIGE associated with voclosporin, a newer calcineurin inhibitor used primarily to treat lupus nephritis.
Francesca Racca   +2 more
wiley   +1 more source

A Case Series of Valve‐in‐Valve Transcatheter Aortic Valve Replacement in Stentless Bioprosthetic Valves Using Self‐Expanding Platform With Minimalist Approach

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Valve‐in‐valve (ViV) Transcatheter aortic valve replacement (TAVR) has emerged as a valid treatment option in symptomatic patients with failed aortic bioprosthetic valves, most especially in those with intermediate, high or prohibitive risk of surgery. Due to the unique design of stentless bioprosthetic valves with absence of visible posts and
Adeogo Akinwale Olusan   +3 more
wiley   +1 more source

Role of High total protein in gallbladder bile in the formation of cholesterol gallstones. [PDF]

open access: yes, 1991
While it is generally accepted that cholesterol supersaturation of bile is of key importance in the rapid formation of cholesterol crystals, the role of total biliary protein and pH in the pathogenesis of cholesterol gallstones is less well understood ...
Abell   +37 more
core   +1 more source

Implementing Pre‐Emptive Pharmacogenetics: Impact of Early Pharmacogenetic Screening in a Pediatric Oncology Cohort of 1,151 Subjects

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
In pediatric oncology, pharmacogenetic guidelines are underutilized and the potential impact of pre‐emptive pharmacogenetic screening remains largely unexplored despite this field's need for individualized approaches. While comprehensive pharmacogenetic guidelines are not yet available for all anticancer drugs, evidence‐based recommendations exist for ...
Emma C. Bernsen   +12 more
wiley   +1 more source

Omeprazole-Domperidone Fixed Dose Combination vs Omeprazole Monotherapy: A Phase 4, Open-Label, Comparative, Parallel Randomized Controlled Study in Mild to Moderate Gastroesophageal Reflux Disease

open access: yesClinical Medicine Insights: Gastroenterology, 2017
Aim: To compare the efficacy and safety of omeprazole-domperidone combination vs omeprazole monotherapy in gastroesophageal reflux disease (GERD). Methods: In a comparative, randomized controlled, phase 4 study, outpatients with GERD were randomly ...
KY Marakhouski   +3 more
doaj   +1 more source

Clinical analysis and literature review of 6 cases of burning mouth syndrome-like symptoms caused by the long-term oral administration of omeprazole

open access: yes口腔疾病防治, 2021
Objective To analyze the oral adverse drug reactions induced by omeprazole and provide a reference for rational clinical drug use. Methods From January 2019 to June 2020, the clinical data of patients with burning mouth syndrome caused by omeprazole were
LU Ying, YAN Qizhang, YU Dahai
doaj   +1 more source

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