Results 41 to 50 of about 24,384 (185)

Omeprazole Minimally Alters the Fecal Microbial Community in Six Cats: A Pilot Study

Frontiers in Veterinary Science, 2018
Although they have historically been thought of as safe medications, proton pump inhibitors such as omeprazole have been associated with an increased risk of enteric, particularly Clostridium difficile, infections in people.
Sarah M. Schmid, Jan S. Suchodolski, Josh M. Price, M. K. Tolbert   +3 more
doaj   +1 more source

Temporal and geographical patterns of nitazene detections in drug samples and biospecimens in the United States, 2019–2024

Addiction, EarlyView.
Abstract Background and aims Nitazenes are a novel subclass of synthetic opioids that have been increasingly implicated in the United States (US) overdose crisis. Despite their growing presence in the illicit drug supply, national trends have not been systematically evaluated.
David T. Zhu, Nicole D. Fitzgerald, Joseph J. Palamar, Alex J. Krotulski   +3 more
wiley   +1 more source

Impact of obesity and roux‐en‐Y gastric bypass on the pharmacokinetics of (R)‐ and (S)‐omeprazole and intragastric pH

CPT: Pharmacometrics & Systems Pharmacology
This study employed physiologically‐based pharmacokinetic–pharmacodynamics (PBPK/PD) modeling to predict the effect of obesity and gastric bypass surgery on the pharmacokinetics and intragastric pH following omeprazole treatment.
Leandro F. Pippa, Valvanera Vozmediano, Lieke Mitrov‐Winkelmolen, Daan Touw, Amira Soliman, Rodrigo Cristofoletti, Wilson Salgado Junior, Natalia Valadares de Moraes   +7 more
doaj   +1 more source

Medical therapy using omeprazole in 12 hydrocephalic dogs: clinical, diagnostic, and therapeutic findings [PDF]

Pesquisa Veterinária Brasileira
: According to experimental studies with healthy dogs, omeprazole might decrease the CSF production by about 26%; therefore, book texts have been suggested the usage of omeprazole in medical protocols for hydrocephalus treatment.
Lidianne F. Pelegrini, Natalino F. Silva, Olga P.S. Campos, Clazielen C. Nery, Felipe M. Silva, Raquel S. Lemos, Kelly C.I. Yamauchi, Alexandre M. Amude   +7 more
doaj   +2 more sources

Profiling and Identification of Omeprazole Metabolites in Mouse Brain and Plasma by Isotope Ratio-Monitoring Liquid Chromatography-Mass Spectrometric Method

Life, 2020
Neuro–inflammation is known to be one of the pathogenesis for the degenerative central nervous system (CNS) disease. Recently various approaches for the treatment of brain diseases by controlling neuro-inflammation in the brain have been introduced.
Seok-Ho Shin, Yuri Park, Min-Ho Park, Jin-Ju Byeon, Byeong ill Lee, Jangmi Choi, Young G. Shin   +6 more
doaj   +1 more source

Altered Pathogen Spectrum of Spontaneous Bacterial Peritonitis in Patients Treated With Proton Pump Inhibitors

Alimentary Pharmacology &Therapeutics, EarlyView.
This multicenter, observational study reveals distinct alterations in the microbial spectrum of spontaneous bacterial peritonitis (SBP) associated with proton pump inhibitor use. These results are especially relevant for guiding empiric antibiotic therapy of SBP.
Philip Kitchen, Sarah L. Schütte, Tammo L. Tergast, Benjamin Maasoumy, Leonie Braun, Ulrich vor dem Esche, Georg Häcker, Marcus M. Mücke, Marlene Reincke, Michael Schultheiss, Robert Thimme, Siegbert Rieg, Dominik Bettinger, Lukas Sturm   +13 more
wiley   +1 more source

Omeprazole Inhibits Cell Proliferation and Induces G0/G1 Cell Cycle Arrest through Up-regulating miR-203a-3p Expression in Barrett’s Esophagus Cells

Frontiers in Pharmacology, 2018
Existing data suggest that proton pump inhibitors (PPIs), particularly omeprazole, have significant anti-tumor action in monotherapy and or combination chemotherapy.
Yichao Hou, Qiang Hu, Jiao Huang, Hua Xiong   +3 more
doaj   +1 more source

Epicutaneous and Drug Provocation Testing in Severe Cutaneous Adverse Reactions: A 20‐Year Single‐Centre Experience

Contact Dermatitis, EarlyView.
This study provides reassuring evidence in favour of early skin testing in patients with SCARs, argues against the necessity of a 6‐month delay, and underscores the pivotal role of oral provocation tests in the safe reintroduction of essential therapies. ABSTRACT Background Identifying and discontinuing the offending drug(s) in severe cutaneous adverse
Zohra Chadli, Khadija Mansour, Ghada Jaouahdou, Manel Ben Belgacem, Yosra Soua, Nadia Ben Fredj, Jameleddine Zili, Haifa Ben Romdhane, Karim Aouam   +8 more
wiley   +1 more source

Cardiovascular Outcomes Associated With Clinical Use of Citalopram and Omeprazole: A Nationwide Population‐Based Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Recent studies have raised concerns about the reduced efficacy of citalopram when used concurrently with proton pump inhibitors. The aim of this study was to evaluate the associations between clinical use of citalopram and omeprazole and the ...
Wen‐Tung Wu, Chun‐Teng Tsai, Yu‐Ching Chou, Po‐Ming Ku, Yong‐Chen Chen, San‐Lin You, Chi‐Feng Hung, Chien‐An Sun   +7 more
doaj   +1 more source

Role of Omeprazole as An Antifungal Agent [PDF]

Engineering and Technology Journal, 2011
The antifungal activity of various concentrations of omeprazole (0.1mg/ml, 0.25mg/ml, 0.5mg/ml, 1mg/ml, 2.5mg/ml, 5mg/ml, 10mg/ml, and 20mg/ml) were studied in different pH media (5 and 7) against Aspergillus niger, and Trichophyton urbrum.The laboratory
Omar A. Al-Mukhtar, Suhad A. Ahmad, Raya R. Jabri, Ali A. Juwaied   +3 more
doaj   +1 more source