Results 71 to 80 of about 24,384 (185)

Combination Versus Monotherapy in Acute Anti‐LGI1 Encephalitis: A Real‐World Dose Optimization Analysis

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
Combined IVIg and 500 mg/day IVMP achieve superior efficacy over monotherapies in anti‐LGI1 encephalitis, with optimal safety. Higher‐dose IVMP (1000 mg) accelerates response but increases adverse events, particularly in diabetic patients. Cognitive deficits persist post‐treatment, necessitating long‐term management.
Yao Tan   +6 more
wiley   +1 more source

Omeprazole exacerbates intervertebral disc degeneration through Caspase-3 mediated apoptosis of nucleus pulposus cells: a Mendelian randomization, network toxicology, and in vitro experimental study

open access: yesJournal of Orthopaedic Surgery and Research
Objective To investigate the causal correlation and toxicological mechanisms of omeprazole in intervertebral disc degeneration (IVDD), alongside a particular emphasis on Caspase-3 (CASP3) mediated apoptosis of nucleus pulposus cells (NPCs).
Yuchao Jia   +3 more
doaj   +1 more source

Gastric pH in Rats: Key Determinant for Preclinical Evaluation of pH-dependent Oral Drug Absorption

open access: yesPrague Medical Report, 2019
Data on gastric pH in rats to be used in preclinical models for pH-dependent drug absorption are still limited or contradictory. The aim of this study was to describe gastric pH in rats at fasted state and to evaluate its changes induced by pentagastrin ...
Martin Šíma   +5 more
doaj   +1 more source

Analysis of the content and user interactions with a veterinary critically appraised topic (CAT) database: A 10‐year review

open access: yesVeterinary Record Open, Volume 13, Issue 1, June 2026.
Abstract Introduction A cornerstone of evidence‐based veterinary medicine is the use of research‐based evidence to inform clinical decision making. There are a number of evidence‐based resources available for veterinary professionals to use at the point of care, but it is unknown how and what specific topics users are seeking.
Davide Messina   +5 more
wiley   +1 more source

Myocardial toxicity in two dogs with natural exposure to ractopamine

open access: yesVeterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract Two dogs that lived in a farm setting were presented to the Texas A&M University Veterinary Medical Teaching Hospital's Emergency Service exhibiting muscle tremors and ventricular arrhythmias following ingestion of ractopamine, a ß‐2 agonist feed‐additive used in beef cattle, pigs and turkeys intended for slaughter to increase muscle mass. The
Sophie Tippit   +3 more
wiley   +1 more source

Spontaneous resolution of a gastro‐gastric intussusception in a dog: Diagnostic approach and clinical implications

open access: yesVeterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract A 7‐month‐old, male, entire Dalmatian dog presented with acute‐onset haematemesis. Following symptomatic medical treatment, vomiting resolved, although the dog remained subdued and inappetent. True gastro‐gastric intussusception was suspected on abdominal radiography and ultrasonography and was confirmed by contrast‐enhanced computed ...
Afroditi Evangelia Pontikaki   +4 more
wiley   +1 more source

The Clinical Manifestation of Homozygous Huntington's Disease

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Huntington's disease is an incurable neurodegenerative disease with deficits in many areas including cognitive, psychiatric, and most notably, motor. It is autosomal dominant, meaning one affected allele is enough to express the condition.
Brishti Sengupta, Pritha Dasgupta
wiley   +1 more source

Appropriateness of Omeprazole Prescribing in Quebec’s Senior Population

open access: yesCanadian Journal of Gastroenterology, 2000
BACKGROUND: Prescribing omeprazole for the treatment of digestive disorders accounts for an important part of the costs in Quebec’s drug benefit plan. In July 1993, the Quebec drug program listed omeprazole, with restriction, in its formulary. On January
Jean-Pierre Grégoire   +3 more
doaj   +1 more source

Beyond the Wheeze: Incidental Diagnosis of Eosinophilic Oesophagitis in a Young Child With Asthma‐Like Symptoms

open access: yes
Journal of Paediatrics and Child Health, EarlyView.
Sameena Tabassum   +3 more
wiley   +1 more source

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