Results 71 to 80 of about 73,909 (338)

Double‐blinded placebo‐controlled clinical trial of prophylactic omeprazole in dogs treated surgically for acute thoracolumbar intervertebral disc extrusion

open access: yesJournal of Veterinary Internal Medicine, 2023
Background Proton pump inhibitors are administered prophylactically in dogs treated surgically for acute thoracolumbar intervertebral disc extrusion (TL‐IVDE).
Jaya M. Mehra   +5 more
doaj   +1 more source

Metoclopramide Neurological Side Effects Screening; A Pharmacovigilence Study in Romanian Community Pharmacies [PDF]

open access: yes, 2015
Background. Metoclopramide is a pharmacological agent frequently used in therapy against nausea and vomiting that can occur in indigestion, motion sickness, gastric ulcer, pyloric spasm and after surgery as a side effect of some anesthetics.
Junghină, Adrian   +4 more
core   +3 more sources

Pharmacogenomic testing and its future in community pharmacy [PDF]

open access: yes, 2020
Although it is common to see pharmacogenomic testing used North America and Australia, it is not yet part of practice in the UK. With the promise of genomic screening becoming part of the NHS, pharmacists must equip themselves with a knowledge of how the
Wright, David, Youssef, Essra
core   +1 more source

A Randomized, Double‐Blind, Placebo‐Controlled Pilot Trial With Open‐Label Extension of Sirona, a Hydrogel for Weight Loss

open access: yesObesity, EarlyView.
ABSTRACT Objective This study investigated the safety, tolerability, and preliminary efficacy of Sirona, a novel gastro‐retentive, dual‐network polymer for weight management. Methods This pilot trial comprised a randomized, parallel‐group, double‐blind, placebo‐controlled (3:1 ratio), 12‐week period, with a 12‐week open‐label extension (OLE), in ...
James P. Byrne   +9 more
wiley   +1 more source

Drug-drug interactions in repeat prescriptions at village dispensaries (bereg) in Malta [PDF]

open access: yes, 2013
Inappropriate treatments and drug-drug interactions (DDIs) are known to occur in settings where repeat prescriptions are issued. In view of this, a study was carried out to document any such problematic drug prescribing and propose changes that would
Bugeja, Anton
core  

Low Helicobacter pylori eradication rates with 4- and 7-day regimens in an Iranian population [PDF]

open access: yes
Background: In Iran, there is insufficient information on the efficacy of Helicobacter pylori eradication regimens shorter than 10 days. This study aims at assessing the efficacy of 4- and 7-day H. pylori eradication regimens in a high-incidence area of
بابایی, مسعود   +15 more
core   +1 more source

A Population Pharmacokinetic Approach to Understand the Effect of Efavirenz on CYP3A Activity in Healthy Volunteers Using Midazolam as a Probe

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Efavirenz induces and inhibits multiple drug‐metabolizing enzymes, contributing to significant drug–drug interactions. This study quantified the impact of multiple doses of efavirenz on CYP3A activity via midazolam metabolism using a population pharmacokinetic approach.
Kimberly S. Collins   +6 more
wiley   +1 more source

Omeprazole Inhibits Cell Proliferation and Induces G0/G1 Cell Cycle Arrest through Up-regulating miR-203a-3p Expression in Barrett’s Esophagus Cells

open access: yesFrontiers in Pharmacology, 2018
Existing data suggest that proton pump inhibitors (PPIs), particularly omeprazole, have significant anti-tumor action in monotherapy and or combination chemotherapy.
Yichao Hou   +3 more
doaj   +1 more source

Impact of creatinine clearance on helicobacter pylori eradication rate in patients with peptic ulcer disease [PDF]

open access: yes, 2015
Introduction. Gastrointestinal complaints are common in patients with kidney failure. The aim of this study was to investigate the effect of creatinine clearance on Helicobacter pylori (HP) eradication rate in patients with peptic ulcer disease ...
Alimadadi, M.   +6 more
core  

Degradation of lansoprazole and omeprazole in the aquatic environment [PDF]

open access: yes, 2006
Lansoprazole and omeprazole degrade in water leading to sulfides, benzimidazolones and a red complex material. Degradation is accelerated in acid medium and by solar simulator irradiation.
BRIGANTE M.   +5 more
core   +1 more source

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