Results 51 to 60 of about 77,382 (200)

Systematic Review: Proteomics-Driven Multi-Omics Integration for Alzheimer’s Disease Pathology and Precision Medicine

open access: yesNeurology International
Background: Neurodegenerative diseases remain a central topic in biomedical research, with Alzheimer’s disease (AD) being the most extensively studied. Recent advances in multi-omics integration, particularly proteomics-based approaches, have enabled a ...
Jonathan Mingsong Dong, Huan Zhong
doaj   +1 more source

Totoro: Identifying Active Reactions During the Transient State for Metabolic Perturbations

open access: yesFrontiers in Genetics, 2022
Motivation: The increasing availability of metabolomic data and their analysis are improving the understanding of cellular mechanisms and how biological systems respond to different perturbations.
Mariana Galvão Ferrarini   +13 more
doaj   +1 more source

Genomic prediction powered by multi-omics data

open access: yesFrontiers in Genetics
Genomic selection (GS) has transformed plant breeding by enabling early and accurate prediction of complex traits. However, its predictive performance is often constrained by the limited information captured through genomic markers alone, especially for ...
Osval A. Montesinos-López   +8 more
doaj   +1 more source

Integrative meta-omics in Galaxy and beyond

open access: yesEnvironmental Microbiome, 2023
Abstract Background ‘Omics methods have empowered scientists to tackle the complexity of microbial communities on a scale not attainable before. Individually, omics analyses can provide great insight; while combined as “meta-omics”, they enhance the understanding of which organisms occupy specific metabolic niches, how ...
Schiml, Valerie C.   +11 more
openaire   +4 more sources

Application of Omics and Systems Medicine in Bladder Cancer

open access: yes, 2017
Bladder cancer (BC) is the ninth most common cancer in the world. Smoking remains the main disease risk factor which is responsible for about half of the diagnosed BC cases.
Frantzi M.   +3 more
core   +1 more source

Progress of metabolomics‐centric multi‐omics research in medicine

open access: yesiMetaOmics
Metabolomics reveals molecular changes at the metabolic level during biological processes. Recent advancements, particularly through integration with other omics and artificial intelligence (AI), are advancing metabolic data analysis and multi‐omics ...
Ziyi Wang   +6 more
doaj   +1 more source

Integration of the Microbiome, Metabolome and Transcriptome Reveals Escherichia coli F17 Susceptibility of Sheep

open access: yesAnimals, 2023
Escherichia coli (E. coli) F17 is one of the most common pathogens causing diarrhea in farm livestock. In the previous study, we accessed the transcriptomic and microbiomic profile of E.
Weihao Chen   +10 more
doaj   +1 more source

A workflow for data integration, analysis, and metabolite annotation for untargeted metabolomics [PDF]

open access: yes, 2019
Metabolomics is the youngest of the “omics” disciplines and it is regarded as a promising approach to understand the metabolic changes that can occur in particular conditions and to identify new biomarkers. We present here a workflow for data integration,
L. Campo   +9 more
core  

Toward the integration of Omics data in epidemiological studies: still a "long and winding road"

open access: yes, 2016
Primary and secondary prevention can highly benefit a personalized medicine approach through the accurate discrimination of individuals at high risk of developing a specific disease from those at moderate and low risk. To this end precise risk prediction
Pineda, S   +18 more
core   +1 more source

BRANEnet : embedding multilayer networks for omics data integration

open access: yes, 2022
International audienceGene expression is regulated at different molecular levels, including chromatin accessibility, transcription, RNA maturation, and transport. These regulatory mechanisms have strong connections with cellular metabolism.
Frédérique Bidard   +10 more
core   +1 more source

Home - About - Disclaimer - Privacy