Results 21 to 30 of about 577 (167)

Preferences for Attributes of Sodium Oxybate Treatment: A Discrete Choice Experiment in Patients with Narcolepsy [PDF]

Patient Preference and Adherence, 2022
Jordan Dubow,1 Alon Y Avidan,2 Bruce Corser,3 Amod Athavale,4 David Seiden,1 Clete Kushida5 1Avadel Pharmaceuticals, Chesterfield, MO, USA; 2Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; 3Sleep Management ...
Dubow J, Avidan AY, Corser B, Athavale A, Seiden D, Kushida C   +5 more
doaj   +2 more sources

Long-Term Treatment of Narcolepsy and Idiopathic Hypersomnia with Low-Sodium Oxybate [PDF]

Nature and Science of Sleep, 2023
Logan D Schneider,1 Anne Marie Morse,2 Michael J Strunc,3 Joyce K Lee-Iannotti,4 Richard K Bogan5 1Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA; 2Janet Weis Children’s Hospital, Geisinger ...
Schneider LD, Morse AM, Strunc MJ, Lee-Iannotti JK, Bogan RK   +4 more
doaj   +2 more sources

Efficacy and Safety of Lower-Sodium Oxybate in an Open-Label Titration Period of a Phase 3 Clinical Study in Adults with Idiopathic Hypersomnia [PDF]

Nature and Science of Sleep, 2022
Michael J Thorpy,1 Isabelle Arnulf,2 Nancy Foldvary-Schaefer,3 Anne Marie Morse,4 Karel Šonka,5 Patricia Chandler,6 Luke Hickey,7 Abby Chen,6 Jed Black,6,8 Amanda Sterkel,6 Dan Chen,9 Richard K Bogan,10 Yves Dauvilliers11,12 1Albert Einstein ...
Thorpy MJ, Arnulf I, Foldvary-Schaefer N, Morse AM, Šonka K, Chandler P, Hickey L, Chen A, Black J, Sterkel A, Chen D, Bogan RK, Dauvilliers Y   +12 more
doaj   +2 more sources

Dissolution of Once-Nightly Sodium Oxybate in Soft Foods and Alternative Liquid Reconstitution Vehicles

Clinical Therapeutics
PURPOSE Narcolepsy is a chronic neurologic disorder characterized by excessive daytime sleepiness (EDS) and can occur with or without cataplexy. Once-nightly sodium oxybate (ON-SXB) is approved for the treatment of cataplexy or EDS in patients 7 years of
Maggie Lavender, Anne Marie Morse, Bahador Mark Tafazoli, Feri Ascencion, Ellen Wermter, Laura B. Herpel, Jennifer Gudeman, William John Schaefer, Jason Vaughn   +8 more
openaire   +2 more sources

Efficacy of once-nightly sodium oxybate (FT218) on daytime symptoms in individuals with narcolepsy with or without concomitant alerting agent use: A post hoc analysis from the phase 3 REST-ON trial.

Sleep Medicine
OBJECTIVE/BACKGROUND Extended-release, once-nightly sodium oxybate (ON-SXB) significantly improved narcolepsy symptoms in participants in the phase 3, randomized, double-blind, placebo-controlled REST-ON trial.
Y. Dauvilliers, Thomas Roth, Richard K Bogan, M.J. Thorpy, A. Morse, A. Roy, Jennifer Gudeman   +6 more
semanticscholar   +3 more sources

Understanding the Patient Experience with Twice-Nightly Sodium Oxybate Therapy for Narcolepsy: A Social Listening Experiment. [PDF]

Brain Sci
Background/Objectives: Narcolepsy is a chronic neurologic disorder associated with substantial challenges that affect the social, emotional, and financial quality-of-life domains. A social listening analysis and structured survey were conducted to better
Picone M, Ascencion F, Horsnell M, Zhang E, Dougherty L, DeFelice C, Flurie M, Cook R, Morse AM, Ortiz LE, Wassman ER, Gudeman J.   +11 more
europepmc   +2 more sources

The effect and safety of sleep interventions on suicidal thoughts and behavior - A systematic review and meta-analyses. [PDF]

Sleep Med X
Background: Sleep disturbances are a risk factor for suicidal ideation, suicide attempts and suicide. While recent findings suggest that improving sleep by psychotherapeutic sleep interventions exerts a positive effect on suicidality, there are also ...
von Spreckelsen P, Schouten D, Waslam NG, Katuin P, Heering HD, Planting C, Antypa N, Kivelä L, Lancel M, Schweren LJS.   +9 more
europepmc   +3 more sources

Pharmacologic treatment of fibromyalgia: an update. [PDF]

Front Pharmacol
Fibromyalgia (FM) is a chronic pain disorder characterized by widespread musculoskeletal pain, frequently accompanied by fatigue, sleep disturbances, cognitive dysfunction, and mood disorders.
Li Y, Li Y, Wu S, Long M, Chen X, Wang Y, Zhao J, He B, Chang C, Jiao J.   +9 more
europepmc   +3 more sources

0607 Improvement in Sleep Latency With FT218 (Once-Nightly Sodium Oxybate): Analysis From the Phase 3 REST-ON Clinical Trial

SLEEP, 2023
Abstract Introduction In the phase 3 REST-ON trial (NCT02720744), mean sleep latency on the Maintenance of Wakefulness Test (MWT) was significantly improved vs placebo with investigational, extended-release once-nightly sodium oxybate (FT218 [ON-SXB]; P< 0.001).
Michael Thorpy, Colin Shapiro, Clete Kushida, Maurice Ohayon, Jordan Dubow, Jennifer Gudeman   +5 more
openaire   +2 more sources

Letter to the Editor regarding: “Implications of Oxybate Dosing Regimen for Sleep, Sleep Architecture, and Disrupted Nighttime Sleep in Patients with Narcolepsy: A Commentary” by R. Rosenberg et al [PDF]

Neurology and Therapy
Thomas Roth
doaj   +2 more sources