Results 51 to 60 of about 1,677,629 (133)

Once-Nightly Sodium Oxybate (FT218) Demonstrated Improvement of Symptoms in a Phase 3 Randomized Clinical Trial in Patients With Narcolepsy

, 2021
STUDY OBJECTIVES: To assess the efficacy and safety of FT218, a novel once-nightly formulation of sodium oxybate (ON-SXB), in patients with narcolepsy in the phase 3 REST-ON trial.
Roy, Asim, Kushida, Clete A, Shapiro, Colin M, Ajayi, Akinyemi O, Dauvilliers, Yves, Seiden, David, Dubow, Jordan, Rosenberg, Russell, Thorpy, Michael J, Corser, Bruce C, Roth, Thomas   +10 more
core  

Effect of sodium oxybate on disrupted nighttime sleep in patients with narcolepsy

, 2017
This post hoc analysis evaluated the dose-related effects of sodium oxybate on sleep continuity and nocturnal sleep quality in patients with narcolepsy-cataplexy.
Dauvilliers, Yves, Dynin, Efim, Guinta, Diane, Alvarez-Horine, Sarah, Roth, Thomas, Black, Jed   +5 more
core   +1 more source

Efficiency of sodium oxybate in episodic cluster headache

, 2013
We report the case of a 60-year-old man suffering from episodic cluster headache treated successfully with sodium oxybate.
Hidalgo, H, Kallweit, U, Uhl, V, Gantenbein, A R, Sándor, P S   +4 more
core   +1 more source

The cost-utility of sodium oxybate as narcolepsy treatment

, 2017
AIMS AND OBJECTIVES: Based on class-I studies, sodium oxybate is regarded as a first-line treatment for both EDS and cataplexy. The cost-effectiveness of sodium oxybate is largely unknown, though.
Kjellberg, J., Jennum, P., Wasling, Pontus,, H. Meinild, Wasling, P, J. Kjellberg, Jennum, P, P. Wasling, K. Bolin, P. Berling, Bolin, Kristian,, Bolin, K, Berling, P, Meinild, H., Meinild, H, P. Jennum, Berling, P., Kjellberg, J   +17 more
core   +1 more source

COMPOSITE RESPONSE WITH ONCE-NIGHTLY SODIUM OXYBATE: SYMPTOM IMPROVEMENT IN PARTICIPANTS WITH NARCOLEPSY TYPE 1

Introduction: A novel once-nightly formulation of sodium oxybate (ON-SXB; LUMRYZ™) was investigated in patients with narcolepsy type 1 (NT1) and 2 (NT2) in the phase 3 REST-ON trial (NCT02720744).
Dauvilliers, Yves, Harsh, John, Thorpy, Michael J, Ortiz, Luis E, Morse, Anne M, Kushida, Clete, Roth, Thomas, Gudeman, Jennifer   +7 more
core   +1 more source

Characterization of patients who had ≥5% weight loss with once-nightly sodium oxybate: post hoc analysis from REST-ON

Introduction: Narcolepsy, particularly type 1 (NT1), is often comorbid with obesity. Efficacy and safety of a once-at-bedtime oxybate (LUMRYZ™, sodium oxybate for extended-release oral suspension, CIII [FT218; once-nightly sodium oxybate (ON-SXB)]), were
Dauvilliers, Yves, Dubow, Jordan, Bogan, Richard, Morse, Anne M, Roy, A., Roth, Thomas, Gudeman, Jennifer   +6 more
core   +1 more source

Sodium oxybate plus nalmefene for the treatment of alcohol use disorder: A case series.

, 2016
The treatment of alcohol use disorder still remains a challenge. The efficacy of the combined pharmacological treatment for alcohol use disorder has been widely investigated with controversial results.
BERNARDI, MAURO, Addolorato, G, D'Amore, Antonio, Maremmani, Angelo G. I., Caputo, F, Caputo, Francesco Maria, Caputo, Fabio, Addolorato, Giovanni, Maremmani, A, D’Amore, A, DOMENICALI, MARCO, Zoli, Giorgio, Maremmani, Icro, Zoli, G   +13 more
core   +1 more source

Interview with Natasha Nightly

, 2018
Lane Wagner, stage name Natasha Noir Nightly, is interviewed by Sarah Steiner as a part of the Gender and Sexuality Oral History project. Wagner, who identifies as a pansexual, cisgender male, is a bearded drag queen and part of the drag family House ...
Steiner, Sarah K.;
core  

CONSISTENT EFFICACY OF ONCE-NIGHTLY SODIUM OXYBATE ACROSS PATIENT DEMOGRAPHIC AND BASELINE DISEASE CHARACTERISTICS

Introduction: Once-nightly sodium oxybate (ON-SXB; LUMRYZ™) was investigated in patients with narcolepsy type 1 (NT1) or 2 (NT2) in the phase 3 REST-ON trial; treatment with 6, 7.5, and 9 g demonstrated significant improvements vs placebo (all P\u3c 0 ...
Dauvilliers, Yves, Harsh, John, Thorpy, Michael J, Morse, Anne M, Ortiz, Luis E, Kushida, Clete, Roth, Thomas, Gudeman, Jennifer   +7 more
core   +1 more source

Efficacy of Once-Nightly Sodium Oxybate in Patients with Narcolepsy: Post Hoc Analyses of Sensitivity, Effect Size, and Numbers Needed to Treat from the Phase 3 REST-ON Trial. [PDF]

CNS Drugs
Roth T, Thorpy MJ, Kushida CA, Gudeman J.   +3 more
europepmc   +1 more source