Results 51 to 60 of about 377 (154)

Sleep disorders in children [PDF]

, 2010
Although sleep disorders such as insomnia and obstructive sleep apnea are common in both children and adults, the clinical features and treatments for these conditions differ considerably between these two populations.
Hoban, Timothy F.
core   +1 more source

Daytime sleepiness and BMI exhibit gender and age differences in patients with central disorders of hypersomnolence

Journal of Sleep Research, Volume 34, Issue 3, June 2025.
In a cohort of central disorders of hypersomnolence, specifically women with idiopathic hypersomnia showed a marked subjective daytime sleepiness peak in the early 30s, while the body mass index only started to rise at that age. Better understanding of the pathophysiology of these gender and age‐specific characteristics will support tailored ...
Laura Ferrazzini, Markus Schmidt, Zhongxing Zhang, Ramin Khatami, Yves Dauvilliers, Lucie Barateau, Geert Mayer, Fabio Pizza, Giuseppe Plazzi, Jari K. Gool, Rolf Fronczek, Gert Jan Lammers, Rafael del Rio‐Villegas, Rosa Peraita‐Adrados, Markku Partinen, Sebastiaan Overeem, Karel Sonka, Joan Santamaria, Raphael Heinzer, Francesca Canellas, Antonio Martins da Silva, Birgit Högl, Christian Veauthier, Aleksandra Wierzbicka, Eva Feketeova, Jitka Buskova, Michel Lecendreux, Silvia Miano, Ulf Kallweit, Anna Heidbreder, Claudio L. A. Bassetti, Julia van der Meer   +31 more
wiley   +1 more source

Growth Hormone Deficiency and Excessive Sleepiness: A Case Report and Review of the Literature [PDF]

, 2019
The somatotropic axis is intricately involved in normal sleep, as evidenced by the fact that hypothalamic growth hormone-releasing hormone (GHRH) has sleep promoting effects and pituitary growth hormone (GH) release is strongly associated with slow-wave ...
Eugster, Erica, Gohil, Anisha
core   +1 more source

International Swiss Primary Hypersomnolence and Narcolepsy Cohort Study (iSPHYNCS): the impact of psychiatric comorbidities on daily life in central disorders of hypersomnolence—a vicious circle

Journal of Sleep Research, Volume 34, Issue 3, June 2025.
Summary Presence of psychiatric comorbidities is well documented in narcolepsy type‐1 (NT1) but there are limited data on patients with ‘other central disorders of hypersomnolence’ (OCH). This study aimed to investigate frequency of psychiatric comorbidities in patients with NT1 and OCH, and to evaluate their impact on quality of life and sleep as an ...
Merve Aktan Suzgun, Elena S. Wenz, Julia van der Meer, Livia G. Fregolente, Jan D. Warncke, Silvia Miano, Jens Acker, Mathias Strub, Elisabeth Olliges, Ramin Khatami, Markus H. Schmidt, iSPHYNCS Investigators, Claudio L. A. Bassetti, Sigrid von Manitius   +13 more
wiley   +1 more source

The electroretinography to identify biomarkers of idiopathic hypersomnia and narcolepsy type 1

Journal of Sleep Research, Volume 34, Issue 1, February 2025.
Summary Hypersomnia spectrum disorders are underdiagnosed and poorly treated due to their heterogeneity and absence of biomarkers. The electroretinography has been proposed as a proxy of central dysfunction and has proved to be valuable to differentiate certain psychiatric disorders.
Héloïse Rach, Ulker Kilic‐Huck, Pierre A. Geoffroy, Tristan Bourcier, Sophie Braun, Henri Comtet, Elisabeth Ruppert, Laurence Hugueny, Marc Hebert, Eve Reynaud, Patrice Bourgin   +10 more
wiley   +1 more source

A Stage-Based Approach to Therapy in Parkinson’s Disease [PDF]

, 2019
Parkinson's disease (PD) is a neurodegenerative disorder that features progressive, disabling motor symptoms, such as bradykinesia, rigidity, and resting tremor.
Barbone, Filomena, Bonanni, Laura, Carrarini, Claudia, Di Pietro, Martina, Di Stefano, Vincenzo, Dono, Fedele, Ferri, Laura, Onofrj, Marco, Rispoli, Marianna G, Russo, Mirella, Sensi, Stefano Luca, Thomas, Astrid, Vitale, Michela   +12 more
core   +1 more source

Autonomic cardiovascular control is unaffected in children referred for assessment of excessive daytime sleepiness

Journal of Sleep Research, Volume 34, Issue 1, February 2025.
Summary There is conflicting evidence for impaired autonomic control of heart rate (HR) in adults with narcolepsy and idiopathic hypersomnolence (IH). Despite these chronic hypersomnia conditions primarily being diagnosed around the age of puberty, there are limited studies in children.
Jamilla Francis, Georgina Plunkett, Marisha Shetty, Margot J. Davey, Gillian M. Nixon, Lisa M. Walter, Rosemary S. C. Horne   +6 more
wiley   +1 more source

Custody or release: problem GHB users in police cells, custody, and pre-trial detention [PDF]

, 2013
Gamma-hydroxybutyrate acid (GHB) is a potent depressant of the central nervous system which rapidly enters the bloodstream and produces its effects shortly after ingestion.1 Since the early 1990’s, GHB increasingly became popular as recreational drug ...
Korf, D.J., Nabben, T., Pronk, A.
core   +2 more sources

Loss of rapid eye movement atonia in rapid eye movement sleep behaviour disorder and narcolepsy

Journal of Sleep Research, Volume 34, Issue 1, February 2025.
Summary A reduction of physiological muscle atonia during rapid eye movement sleep is characteristic in patients with rapid eye movement sleep behaviour disorder, however, it can also be found in narcolepsy patients. We evaluated rapid eye movement sleep associated electromyographic activity to set cut‐off values of rapid eye movement sleep without ...
Franziska Edlinger, Marion Böck, Stefan Seidel, Karin Trimmel   +3 more
wiley   +1 more source

Brief of 12 Narcolepsy Patients, Public Interest Organizations, Medical Professionals, and Professors of Law and Medicine as Amici Curiae in Support of Defendants-Appellees (Amended to Add Further Signatories) [PDF]

A prior copy of this brief was filed, inadvertently omitting one signatory. This brief has accordingly been amended to correct the error, reflected in the Certificate as to parties and the ...
Duan, Charles
core   +1 more source