Results 61 to 70 of about 13,454 (262)

Master of Puppets: How Microbiota Drive the Nematoda Ecology and Evolution?

Ecology and Evolution, Volume 15, Issue 8, August 2025.
The nematode microbiota can influence life‐history traits, thereby shaping the species' ecology and evolutionary trajectories. ABSTRACT In recent decades, the microbiota has emerged as a key driver of biological functions in metazoans, and nematodes are no exception.
Víctor José Trejo‐Meléndez, Jorge Contreras‐Garduño   +1 more
wiley   +1 more source

Onchocerciasis transmission in Ghana: persistence under different control strategies and the role of the simuliid vectors. [PDF]

PLoS Neglected Tropical Diseases, 2015
BACKGROUND:The World Health Organization (WHO) aims at eliminating onchocerciasis by 2020 in selected African countries. Current control focuses on community-directed treatment with ivermectin (CDTI).
Poppy H L Lamberton, Robert A Cheke, Peter Winskill, Iñaki Tirados, Martin Walker, Mike Y Osei-Atweneboana, Nana-Kwadwo Biritwum, Anthony Tetteh-Kumah, Daniel A Boakye, Michael D Wilson, Rory J Post, María-Gloria Basañez   +11 more
doaj   +1 more source

PD‐L2 Inhibits Protective Immunity, Th2 Cell Functional Quality, and GATA‐3 Expression During Filarial Nematode Infection

European Journal of Immunology, Volume 55, Issue 8, August 2025.
During filarial nematode infection with Litomosoides sigmodontis, PD‐L2 down‐regulates Th2 cell expression of GATA‐3 and Th2 cytokines and enables parasite survival. Concurrently, B cells suppress protective immunity through a mechanism that does not involve PD‐L2.
Johanna A. Knipper, Sharon M. Campbell, Judith E. Allen, Matthew D. Taylor   +3 more
wiley   +1 more source

The mitogenome of Onchocerca volvulus from the Brazilian Amazonia focus

Memorias do Instituto Oswaldo Cruz, 2016
We report here the first complete mitochondria genome of Onchocerca volvulus from a focus outside of Africa. An O. volvulus mitogenome from the Brazilian Amazonia focus was obtained using a combination of high-throughput and Sanger sequencing ...
James L Crainey, Túllio RR da Silva, Fernando Encinas, Michel A Marín, Ana Carolina P Vicente, Sérgio LB Luz   +5 more
doaj   +1 more source

The Mbam drainage system and onchocerciasis transmission post ivermectin mass drug administration (MDA) campaign, Cameroon.

PLoS Neglected Tropical Diseases, 2021
BackgroundThe impact of large scale Mass Drug Adminstration (MDA) of ivermectin on active onchocerciasis transmission by Simulium damnosum, which transmits the parasite O. volvulus is of great importance for onchocerciasis control programmes.
Raphael Awah Abong, Glory Ngongeh Amambo, Ali Ahamat Hamid, Belinda Agbor Enow, Amuam Andrew Beng, Franck Noel Nietcho, Theobald Mue Nji, Abdel Jelil Njouendou, Manuel Ritter, Mathias Eyong Esum, Kebede Deribe, Jerome Fru Cho, Fanny Fri Fombad, Peter Ivo Enyong, Catherine Poole, Kenneth Pfarr, Achim Hoerauf, Clotilde Carlow, Samuel Wanji   +18 more
doaj   +1 more source

Human infection with Gongylonema pulchrum [PDF]

, 1994
A 43 year old woman developed a painful tumor at the left buccal mucosa. Following local anti-inflammatory treatment a 35 mm long, living female adult worm of Gongylonema pulchrum was extracted from the affected side.
Jelinek, Thomas, Löscher, Thomas
core  

Modelling Neglected Tropical Diseases diagnostics: the sensitivity of skin snips for Onchocerca volvulus in near elimination and surveillance settings. [PDF]

, 2016
BACKGROUND: The African Programme for Onchocerciasis Control has proposed provisional thresholds for the prevalence of microfilariae in humans and of L3 larvae in blackflies, below which mass drug administration (MDA) with ivermectin can be stopped and ...
Attah, Simon K, Basáñez, Maria-Gloria, Bottomley, Christian, Isham, Valerie, Kuesel, Annette C, Lustigman, Sara, Opoku, Nicholas O, Vivas-Martínez, Sarai, Walker, Martin   +8 more
core   +4 more sources

The Burden of Neglected Tropical Diseases in Rwanda: A Scoping Review

Health Science Reports, Volume 8, Issue 8, August 2025.
ABSTRACT Background and Aims Rwanda is among the African countries affected by neglected tropical diseases (NTDs). This scoping review aims to synthesize available information to understand the prevalence, incidence, distribution, morbidity, mortality, and risk factors of NTDs in Rwanda.
Masceline Jenipher Mutsaka‐Makuvaza, Michael Olubusayo Binuyo, Callixte Cyuzuzo, Acsa Igizeneza, Jean Paul Sinumvayo, Oluwaremilekun Grace Ajakaye, Egie Elisha Enabulele, Zororo Chinwadzimba, Ezera Agwu, Nicholas Midzi   +9 more
wiley   +1 more source

Of mice, cattle, and humans: the immunology and treatment of river blindness.

PLoS Neglected Tropical Diseases, 2008
River blindness is a seriously debilitating disease caused by the filarial parasite Onchocerca volvulus, which infects millions in Africa as well as in South and Central America. Research has been hampered by a lack of good animal models, as the parasite
Judith E Allen, Ohene Adjei, Odile Bain, Achim Hoerauf, Wolfgang H Hoffmann, Benjamin L Makepeace, Hartwig Schulz-Key, Vincent N Tanya, Alexander J Trees, Samuel Wanji, David W Taylor   +10 more
doaj   +1 more source

Lipid profiling of the filarial nematodes Onchocerca volvulus, Onchocerca ochengi and Litomosoides sigmodontis reveals the accumulation of nematode-specific ether phospholipids in the host [PDF]

, 2017
Onchocerciasis, a neglected tropical disease prevalent in western and central Africa, is a major health problem and has been targeted for elimination. The causative agent for this disease is the human parasite Onchocerca volvulus.
Doermann, Peter, Hoerauf, Achim, Makepeace, Benjamin L, Peisker, Helga, Pfarr, Kenneth, Tanya, Vincent N, Wewer, Vera   +6 more
core   +1 more source