Results 51 to 60 of about 11,493 (199)

Escalation of Germinal Center Responses in Chronic Litomosoides sigmodontis Filarial Infection

open access: yesEuropean Journal of Immunology, Volume 55, Issue 5, May 2025.
T follicular helper (TFH) cells provide essential help to B cells in germinal centers (GCs). TFH and GC B cell responses are long‐lasting in draining mediastinal lymph nodes of Litomosoides sigmodontis‐infected BALB/c mice, a rodent model of filarial infection. ABSTRACT T follicular helper (TFH) cells are the primary CD4+ T helper cell subset providing
Teresa Steffen   +9 more
wiley   +1 more source

Assessment of community’s knowledge, attitude and practice about onchocerciasis and community directed treatment with Ivermectin in Quara District, north western Ethiopia

open access: yesParasites & Vectors, 2014
Background The African Program for Onchocerciasis Control (APOC) has been working with ultimate goal of reducing the public health and socio-economic problems associated with onchocerciasis within a period of 12–15 years.
Fitsum Weldegebreal   +3 more
doaj   +1 more source

Predicting the environmental suitability for onchocerciasis in Africa as an aid to elimination planning.

open access: yesPLoS Neglected Tropical Diseases, 2021
Recent evidence suggests that, in some foci, elimination of onchocerciasis from Africa may be feasible with mass drug administration (MDA) of ivermectin. To achieve continental elimination of transmission, mapping surveys will need to be conducted across
Elizabeth A Cromwell   +224 more
doaj   +1 more source

Simmering Tensions and Emerging Conflicts Among Key Group Actors Amid Capitalist Transformation in Northern Ghana

open access: yesJournal of Agrarian Change, Volume 25, Issue 2, April 2025.
ABSTRACT A capitalist agrarian transformation is unfolding in northern Ghana, marked by shifts in crop types, rapid increases in farm sizes and deepening rural social differentiation. This paper investigates these dynamics through a mixed‐methods approach across six farming communities in two districts, focusing on how social differentiation ...
Ibrahim Wahab   +3 more
wiley   +1 more source

Community‐based epilepsy care in an onchocerciasis‐endemic area: A 3‐year cohort study in Mahenge, Tanzania

open access: yesEpilepsia, Volume 66, Issue 3, Page 739-752, March 2025.
Abstract Objective In onchocerciasis‐endemic areas, limited access to antiseizure medications (ASMs) contributes to a high epilepsy burden. This study evaluated the impact of a community‐based epilepsy care program in Mahenge, Tanzania, an onchocerciasis‐endemic area with high epilepsy prevalence.
Dan Bhwana   +9 more
wiley   +1 more source

Prevalence of onchocerciasis, attitudes and practices and the treatment coverage after 15 years of mass drug administration with ivermectin in the Tombel Health District, Cameroon [PDF]

open access: gold, 2020
Sharon Mumah Nyagang   +7 more
openalex   +1 more source

Biting rates and relative abundance of Simulium flies under different climatic conditions in an onchocerciasis endemic community in Ghana [PDF]

open access: gold, 2020
Kenneth Bentum Otabil   +6 more
openalex   +1 more source

Ivermectin as a promising therapeutic option for onchocerciasis‐associated epilepsy

open access: yesEpilepsia Open, Volume 10, Issue 1, Page 361-367, February 2025.
Abstract Onchocerciasis, commonly known as river blindness, is a neglected tropical disease caused by the parasite Onchocerca volvulus. It can lead to blindness and visual impairment. Studies have also demonstrated a link between onchocerciasis and epilepsy, with there being a correlation between onchocerciasis endemicity and epilepsy prevalence ...
Mohammad Amin Manavi   +4 more
wiley   +1 more source

FDA‐approved drugs featuring macrocycles or medium‐sized rings

open access: yesArchiv der Pharmazie, Volume 358, Issue 1, January 2025.
This review presents 17 macrocyclic drugs approved by the U.S. Food and Drug Administration during the past 5 years, highlighting their importance and critical role in modern therapeutics, and the innovative synthetic approaches for the construction of these macrocycles.
Youlong Du   +7 more
wiley   +1 more source

Barriers to the National Onchocerciasis Control Programme at operational level in Cameroon: a qualitative assessment of stakeholders’ views

open access: yesParasites & Vectors, 2019
Background The global burden of onchocerciasis is the heaviest in sub-Saharan Africa. Studies have shown the importance of the role of Community-Directed Distributors (CDDs) and nurses in onchocerciasis control, but little is known about their experience
Fanny Nadia Dissak-Delon   +7 more
doaj   +1 more source

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