Results 51 to 60 of about 28,317 (294)

The Role of the Maridi Dam in Causing an Onchocerciasis-Associated Epilepsy Epidemic in Maridi, South Sudan: An Epidemiological, Sociological, and Entomological Study

Pathogens, 2020
Background: An epilepsy prevalence of 4.4% was documented in onchocerciasis-endemic villages close to the Maridi River in South Sudan. We investigated the role of the Maridi dam in causing an onchocerciasis-associated epilepsy epidemic in these villages.
T. Lakwo, S. Raimon, M. Tionga, J. S. Fodjo, P. Alinda, Wilson Sebit, J. Carter, R. Colebunders   +7 more
semanticscholar   +1 more source

Diagnosis of O. volvulus infection via skin exposure to diethylcarbamazine: clinical evaluation of a transdermal delivery technology-based patch

Parasites & Vectors, 2015
Background Elimination of onchocerciasis in Africa is now regarded as an achievable goal in many areas. This makes monitoring changes in infection prevalence a key component of control programmes. Monitoring is currently based on determining the presence
K. Awadzi, Nicholas O. Opoku, Simon K. Attah, Janis K. Lazdins-Helds, Annette C. Kuesel   +4 more
doaj   +1 more source

Persons with onchocerciasis-associated epilepsy and nodding seizures have a more severe form of epilepsy with more cognitive impairment and higher levels of Onchocerca volvulus infection.

Epileptic disorders, 2020
Following previous reports of very high epilepsy prevalence in the onchocerciasis-endemic villages in Maridi County, South Sudan, a study was conducted to investigate the association between the level of Onchocerca volvulus infection, epilepsy, and ...
G. Abd-Elfarag, J. Carter, S. Raimon, Wilson Sebit, Abozer Suliman, J. S. Fodjo, Peter Claver Olore, Kai Puok Biel, Morrish Ojok, M. Y. Logora, R. Colebunders   +10 more
semanticscholar   +1 more source

Co-infection with Onchocerca volvulus and Loa loa microfilariae in central Cameroon: are these two species interacting? [PDF]

, 2006
Ivermectin treatment may induce severe adverse reactions in some individuals heavily infected with Loa loa. This hampers the implementation of mass ivermectin treatment against onchocerciasis in areas where Onchocerca volvulus and L.
Basáñez, M-G, Boussinesq, M, Clarke, P, Filipe, JAN, Gardon, J, Kamgno, J, Pion, SDS   +6 more
core   +1 more source

Evidence of suppression of onchocerciasis transmission in the Venezuelan Amazonian focus. [PDF]

, 2016
BACKGROUND: The World Health Organization (WHO) has set goals for onchocerciasis elimination in Latin America by 2015. Most of the six previously endemic countries are attaining this goal by implementing twice a year (and in some foci, quarterly) mass ...
Basanez, MG, Borges, D, Botto, C, Camacho, O, Coronel, P, Cortez, J, Escalona, M, Flores, J, Frontado, H, Graterol, B, Grillet, ME, Guerra, F, Margeli, H, Morales, AL, Noya-Alarcón, O, Rodriguez, MA, Ríos, D, Tovar, Y, Unnasch, TR, Villamizar, NJ, Vivas-Martínez, S   +20 more
core   +2 more sources

Elimination of onchocerciasis in Africa by 2025: an ambitious target requires ambitious interventions

Infectious Diseases of Poverty, 2019
To achieve the elimination of onchocerciasis transmission in all African countries will entail enormous challenges, as has been highlighted by the active discussion around onchocerciasis intervention strategies and evaluation procedures in this journal ...
Robert Colebunders, Wilma A. Stolk, Joseph Nelson Siewe Fodjo, Charles D. Mackenzie, Adrian Hopkins   +4 more
doaj   +1 more source

The Population Biology and Transmission Dynamics of Loa loa [PDF]

, 2017
Endemic to Central Africa, loiasis – or African eye worm (caused by the filarial nematode Loa loa) – affects more than 10 million people. Despite causing ocular and systemic symptoms, it has typically been considered a benign condition, only of public ...
Basáñez, M-G, Boussinesq, M, Chesnais, C B, Pion, S D S, Walker, M, Whittaker, C   +5 more
core   +1 more source

Current perspective of new anti-Wolbachial and direct-acting macrofilaricidal drugs as treatment strategies for human filariasis

GMS Infectious Diseases, 2022
Filarial diseases like lymphatic filariasis and onchocerciasis belong to the Neglected Tropical Diseases and remain a public health problem in endemic countries.
Ehrens, Alexandra, Hoerauf, Achim, Hübner, Marc P.   +2 more
doaj   +1 more source

The therapeutic efficacy and macrofilaricidal activity of doxycycline for the treatment of river blindness [PDF]

, 2014
Background. Onchocerca volvulus and lymphatic filariae, causing river blindness and elephantiasis, depend on endosymbiotic Wolbachia bacteria for growth, development, fertility, and survival.
Achim Hoerauf, Agwuh, Basáñez, Basáñez, Bosshardt, Cattamanchi, Chib, Churcher, de Andrade, Debrah, Duke, Duke, Gardon, Gelman, Hoerauf, Hoerauf, Hoerauf, Hoerauf, Hoerauf, Hoerauf, Hoerauf, Mand, Mark J. Taylor, Martin Walker, María-Gloria Basáñez, Norton, Osei-Atweneboana, Plaisier, Plaisier, Roberts, Sabine Specht, Specht, Tamarozzi, Taylor, Taylor, Taylor, Taylor, Taylor, Thomas S. Churcher, van Rie, Wanji, Wearing, World Health Organization, Xia   +43 more
core   +1 more source

Evaluation of Lymphatic Filariasis and Onchocerciasis in Three Senegalese Districts Treated for Onchocerciasis with Ivermectin.

PLoS Neglected Tropical Diseases, 2016
In Africa, onchocerciasis and lymphatic filariasis (LF) are co-endemic in many areas. Current efforts to eliminate both diseases are through ivermectin-based mass drug administration (MDA).
Nana O Wilson, Alioune Badara Ly, Vitaliano A Cama, Paul T Cantey, Daniel Cohn, Lamine Diawara, Abdel Direny, Mawo Fall, Karla R Feeser, LeAnne M Fox, Achille Kabore, Amadou F Seck, Ngayo Sy, Daouda Ndiaye, Christine Dubray   +14 more
doaj   +1 more source