Results 231 to 240 of about 845,274 (281)

Cell death: targeting ferroptosis in cancer. [PDF]

Signal Transduct Target Ther
Sabol HM, Galluzzi L, Borriello L.
europepmc   +1 more source

Association of age at pancreatic cancer diagnosis with smoking and drinking: A hospital‐based and meta‐analysis study

Advances in Digestive Medicine, EarlyView.
Abstract Recent trends show an alarming rise in pancreatic cancer prevalence among young individuals. Previous studies have presented differences in age at diagnosis. The study aimed to examine the likelihood of a younger age at diagnosis in individuals exposed to known risk factors, compared with those without exposure.
Ro‐Ting Lin, Louise E. Anthony, Hathaichon Inchai, Lung‐Chang Chien, Chun‐Chieh Yeh, Chi‐Ying Yang, Jaw‐Town Lin   +6 more
wiley   +1 more source

CRISPR/CAS9-based gene editing in cancer therapy: A systematic review and meta-analysis on current status and future directions. [PDF]

Medicine (Baltimore)
Rehman SU, Abbas GH.
europepmc   +1 more source

Single Cell RNA Transcriptomics of Mantle Cell Lymphoma Reveals the Presence of Treatment‐Resistant Subclones at the Time of Diagnosis

American Journal of Hematology, EarlyView.
ABSTRACT Mantle cell lymphoma (MCL) is a B‐cell malignancy with a chronically relapsing clinical course and pronounced genetic heterogeneity. To investigate the clonal dynamics underlying early disease relapse, we performed single‐cell RNA sequencing of paired tumor samples collected at diagnosis and at first relapse. Inference of copy number variants (
Dmitry Manakov, Magdalena Klanova, Michal Kolar, Robert Ivanek, Florian Geier, Julien Roux, Tomas Zikmund, Lucie Winkowska, Eva Kriegova, Jirina Manakova, Liliana Tuskova, Silvia Spanikova, Alexandra Scasna, Marek Trneny, Pavel Klener   +14 more
wiley   +1 more source

Pooled single-cell screen in colorectal cancer defines transcriptional modules linked to oncogenes. [PDF]

Mol Syst Biol
Hollek V, Böhning F, Florez Vargas C, Sieber A, Morkel M, Blüthgen N.   +5 more
europepmc   +1 more source

Correction to: Elf3 drives β-catenin transactivation and associates with poor prognosis in colorectal cancer

Cell Death and Disease
J.-L. Wang, Z.-F. Chen, H.-M. Chen, M.-Y. Wang, X. Kong, Y.-C. Wang, T.-T. Sun, J. Hong, W. Zou, J. Xu, J.-Y. Fang   +10 more
doaj   +1 more source

Genetic Abnormalities and Clinical Management of Fetal Genitourinary System Anomalies in Eastern China

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT To investigate the correlation between genetic abnormalities and fetal genitourinary (GU) anomalies in Eastern China and to provide assistance for the clinical management of fetuses with different types of GU anomalies. Five hundred forty‐five fetuses with GU anomalies were enrolled, undergoing karyotyping, copy number variation sequencing ...
Jie Liang, Jiebin Wu, Lin Zhang, Yunmeng Qi, Yi Wang, Xu Cao, Jingfang Zhai   +6 more
wiley   +1 more source

Prediction of Proto-Oncogene Using Bidirectional GRU and Attention. [PDF]

Asian Pac J Cancer Prev
R D S, A BR.
europepmc   +1 more source

Correction: MiR-198 represses tumor growth and metastasis in colorectal cancer by targeting fucosyl transferase 8

Scientific Reports
Minyu Wang, Jilin Wang, Xuan Kong, Huimin Chen, Yingchao Wang, Miao Qin, Yanwei Lin, Haoyan Chen, Jie Xu, Jie Hong, Ying-Xuan Chen, Weiping Zou, Jing-Yuan Fang   +12 more
doaj   +1 more source

Molecular characterization of the A52 murine hepatocellular carcinoma cell line

Animal Models and Experimental Medicine, EarlyView.
Hepatocellular carcinoma (HCC) is a poor outcome cancer with limited therapeutic choices. To advance therapeutic development we genetically characterized the A52 murine HCC cell line. We noted genetic changes that match a subset of human HCC and this offers the opportunity to test novel targeted therapies in syngeneic mice.
Rhys Gillman, Eun Jin Sun, Miriam Wankell, Matt A. Field, Ulf Schmitz, Lionel Hebbard   +5 more
wiley   +1 more source