Results 261 to 270 of about 845,274 (281)

Modification‐Response Integrated Modules Driven Cyclization‐Dependent Prodrug Self‐Assembly for Reshaping Pro‐Apoptotic Tumor Redox Homeostasis

Exploration, EarlyView.
1. The concept of modification‐response integrated modules was proposed for the first time. 2. Simple, efficient, and feasible drug delivery platforms were developed for systematic regulation of tumor redox microenvironment and reshaping of pro‐apoptotic tumor redox homeostasis.
Yixin Sun, Shiyi Zuo, Wenfeng Zang, Lingxiao Li, Xianbao Shi, Mingzhong Li, Zhonggui He, Bingjun Sun, Jin Sun   +8 more
wiley   +1 more source

Targeting the MAPK Pathway in Brain Tumors: Mechanisms and Therapeutic Opportunities. [PDF]

Cancers (Basel)
Vrachas D, Kosma E, Giannopoulou AI, Margoni A, Gargalionis AN, El-Habr EA, Piperi C, Adamopoulos C.   +7 more
europepmc   +1 more source

Advanced extracellular vesicle immunotherapy

FlexMat, EarlyView.
A diagrammatic depiction of the therapeutic applicability of extracellular vesicles (EVs) in immunotherapy. This review explores the dual roles of tumor‐derived and immune cell‐derived EVs in cancer immunotherapy, discusses recent progress in EV engineering that improve their clinical utility, and evaluates their potential to augment existing ...
Jingjing Zhang, Yunfei Mu, Xianyue Ji, Xiaoting Jiang, Ruiheng Wang, Xianguang Ding, Lianhui Wang   +6 more
wiley   +1 more source

Replication Stress in Cancer: Mechanistic Insights and Therapeutic Opportunities for Radiosensitization. [PDF]

Curr Issues Mol Biol
Vasilopoulos SN, Tremi I, Kotta-Loizou I, Gkikoudi A, Tsitsilonis OE, Havaki S, Georgakilas AG.   +6 more
europepmc   +1 more source

Phytochemicals and Health Benefits of American Ginseng (Panax quinquefolius L.): Current Knowledge and Future Perspectives

Food Safety and Health, EarlyView.
This review summarizes the chemical constituents and functional characteristics of American ginseng, aiming to provide references for its development and application. ABSTRACT American ginseng, a perennial herbaceous plant, is recognized for its significant medicinal properties and has attracted considerable attention due to its diverse phytochemical ...
Wei Geng, Ning Zhou, Jinqian Yu, Yanling Geng, Xiao Wang, Yannan Chen   +5 more
wiley   +1 more source

Bridging East and West: Real-World Clinicogenomic Landscape of Metastatic NSCLC in Türkiye. [PDF]

Genes (Basel)
Canaslan K, Eken E, Bilici M, Balcıoğlu FM, Öztürk B, Çakmak M, Bal Ö, Turhan G, Özdemir F, Arvas H, Urakçı Z, Çiçek E, Turna ZH, Karaoğlu A.   +13 more
europepmc   +1 more source

Urolithin A, a Diet‐Derived Gut Microbial Metabolite Against Pulmonary Hypertension Identified via Molecular Docking, Molecular Dynamics and Surface Plasmon Resonance

Food Safety and Health, EarlyView.
Urolithin A, a gut microbial metabolite, binds TNF to suppress proliferation, inflammation, and oxidative stress, offering a promising microbe‐derived therapeutic avenue for pulmonary hypertension. ABSTRACT Pulmonary hypertension (PH) is a complex and multifactorial disease that poses a significant clinical challenge.
Yujie Qu, Yinghua Huo, Yichen Wang, Yao Mu, Xue Yu, Leiyu Tian, Jian Guo, Xuezhi Yang, Yucai Chen   +8 more
wiley   +1 more source